MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Network Comparison Type	Interaction Map	Value Type	red	Filtered	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1113 to 1162 of 3228 in total

Network Comparison Type  : Divided
Interaction Map  : High confidence
Value Type  : Measured
Filtered  : 1

Rank	description	red	network_comparison	green
1113	phosphoglycerate mutase 1 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13) (phosphoglycerate mutase isozyme b) (pgam-b) (bpg-dependent pgam 1). [swissprot;acc:p18669]	5910.54	1.08968	6440.58
1114	phosphoglycerate mutase 2 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13) (phosphoglycerate mutase isozyme m) (pgam-m) (bpg-dependent pgam 2) (muscle-specific phosphoglycerate mutase). [swissprot;acc:p15259]
1115	5-methyltetrahydrofolate--homocysteine methyltransferase (ec 2.1.1.13) (methionine synthase, vitamin-b12 dependent) (ms). [swissprot;acc:q99707]	5795.13	1.08957	6314.19
1116	dynactin complex 50 kda subunit (50 kda dynein-associated polypeptide) (dynamitin) (dctn-50) (dynactin 2). [swissprot;acc:q13561]	5322.16	1.08948	5798.38
1117	adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236]
1118	adp,atp carrier protein, heart/skeletal muscle isoform t1 (adp/atp translocase 1) (adenine nucleotide translocator 1) (ant 1). [swissprot;acc:p12235]
1119	adp,atp carrier protein, fibroblast isoform (adp/atp translocase 2) (adenine nucleotide translocator 2) (ant 2). [swissprot;acc:p05141]
1120	heat shock factor binding protein 1. [swissprot;acc:o75506]	5915.42	1.08932	6443.77
1121	nucleolar protein nop5 (nucleolar protein 5) (nop58) (hspc120). [swissprot;acc:q9y2x3]	4338.49	1.08929	4725.86
1122	isocitrate dehydrogenase [nadp], mitochondrial precursor (ec 1.1.1.42) (oxalosuccinate decarboxylase) (idh) (nadp+-specific icdh) (idp) (icd-m). [swissprot;acc:p48735]	7937.72	1.08928	8646.38
1123	argininosuccinate lyase (ec 4.3.2.1) (arginosuccinase) (asal). [swissprot;acc:p04424]	5857.48	1.08927	6380.4
1124	transducin-like enhancer protein 2 (esg2). [swissprot;acc:q04725]	6288.27	1.08885	6846.97
1125	transducin-like enhancer protein 1 (esg1). [swissprot;acc:q04724]	6287.07	1.08879	6845.28
1126	importin alpha-6 subunit (karyopherin alpha-5 subunit). [swissprot;acc:o15131]	5792.08	1.08867	6305.67
1127	yip1 interacting factor homolog; yip1p-interacting factor; putative rab5-interacting protein; putative transmembrane protein 54tmp. [refseq;acc:nm_020470]	5790.65	1.08864	6303.92
1128	voltage-gated potassium channel beta-3 subunit (k+ channel beta-3 subunit) (kv-beta-3). [swissprot;acc:o43448]			6303.94
1129	voltage-gated potassium channel beta-1 subunit (k+ channel beta-1 subunit) (kv-beta-1). [swissprot;acc:q14722]			6303.92
1130	similar to putative transmembrane protein; homolog of yeast golgi membrane protein yif1p (yip1p-interacting factor). [refseq;acc:nm_033557]
1131	aflatoxin b1 aldehyde reductase 2 (ec 1.-.-.-) (afb1-ar 2). [swissprot;acc:o95154]
1132	alpha/beta hydrolase domain containing protein 3; lung alpha/beta hydrolase 3. [refseq;acc:nm_138340]
1133	golgi membrane protein sb140; smooth muscle cell associated protein 5. [refseq;acc:nm_030799]
1134	alpha/beta hydrolase domain containing protein 1 isoform 2; lung alpha/beta hydrolase protein 1. [refseq;acc:nm_152870]
1135	methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor (ec 1.2.1.27) (mmsdh). [swissprot;acc:q02252]	5790.67		6303.95
1136	10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984]	5790.65		6303.92
1137	rab acceptor 1 (prenylated); prenylated rab acceptor 1. [refseq;acc:nm_006423]
1138	oligoribonuclease, mitochondrial precursor (ec 3.1.-.-) (small fragment nuclease) (cgi-114). [swissprot;acc:q9y3b8]
1139	choline o-acetyltransferase (ec 2.3.1.6) (choactase) (choline acetylase) (chat). [swissprot;acc:p28329]	5790.66		6303.95
1140	voltage-gated potassium channel beta-2 subunit (k+ channel beta-2 subunit) (kv-beta-2) (hkvbeta2). [swissprot;acc:q13303]	5790.65		6303.93
1141	aflatoxin b1 aldehyde reductase 1 (ec 1.-.-.-) (afb1-ar 1) (aldoketoreductase 7). [swissprot;acc:o43488]
1142	importin alpha-1 subunit (karyopherin alpha-1 subunit) (srp1-beta) (rag cohort protein 2) (nucleoprotein interactor 1) (npi-1). [swissprot;acc:p52294]	5789.07	1.0886	6302.01
1143	homeobox protein engrailed-2 (hu-en-2). [swissprot;acc:p19622]	6281.21	1.08858	6837.61
1144	cpg binding protein (protein containing phd finger and cxxc domain 1). [swissprot;acc:q9p0u4]
1145	40s ribosomal protein s30. [swissprot;acc:q05472]	5893.97		6416.07
1146	activator of basal transcription 1; tata-binding protein-binding protein; basal transcriptional activator. [refseq;acc:nm_013375]	6281.21		6837.61
1147	cytokine-like nuclear factor n-pac. [refseq;acc:nm_032569]
1148	hect type e3 ubiquitin ligase. [refseq;acc:nm_015052]
1149	transducin-like enhancer protein 3 (esg3). [swissprot;acc:q04726]	6280.74	1.08857	6837.01
1150	mstp028 protein. [refseq;acc:nm_031954]	5838.87	1.08841	6355.06
1151	alpha-centractin (centractin) (centrosome-associated actin homolog) (actin-rpv) (arp1). [swissprot;acc:p42024]	5322.74	1.08838	5793.15
1152	beta-centractin (actin-related protein 1b) (arp1b). [swissprot;acc:p42025]
1153	swi/snf related, matrix associated, actin dependent regulator of chromatin subfamily b member 1 (integrase interactor 1 protein) (hsnf5) (baf47). [swissprot;acc:q12824]	5840.01	1.08828	6355.56
1154	tumor necrosis factor, alpha-induced protein 1, endothelial (b12 protein). [swissprot;acc:q13829]	5840.65	1.08821	6355.84
1155	transducin-like enhancer protein 4. [swissprot;acc:q04727]	6270.67	1.0882	6823.73
1156	polymerase delta-interacting protein 1; tnfaip1-like. [refseq;acc:nm_178863]	5840.77	1.08819	6355.89
1157	serine hydroxymethyltransferase, cytosolic (ec 2.1.2.1) (serine methylase) (glycine hydroxymethyltransferase) (shmt). [swissprot;acc:p34896]	5418.33	1.08801	5895.2
1158	delta-aminolevulinic acid dehydratase (ec 4.2.1.24) (porphobilinogen synthase) (aladh). [swissprot;acc:p13716]	5489.18	1.08797	5972.09
1159	kccr13l. [refseq;acc:nm_139179]	5538.8	1.08787	6025.51
1160	dna repair protein rad51 homolog 1 (hrad51) (hsrad51). [swissprot;acc:q06609]
1161	n-acetyltransferase 5 (ec 2.3.1.-). [swissprot;acc:q9y6d2]	5315.76	1.08783	5782.63
1162	nemo-like kinase; likely ortholog of mouse nemo like kinase. [refseq;acc:nm_016231]	5832.13	1.0877	6343.59

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.