MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Gene	Value Type	Rank	red	description	Interaction Map	green	Filtered	network_comparison

Results: HTML CSV LaTeX

Showing element 425 to 474 of 25824 in total

Network Comparison Type  : Divided
Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1

Rank	red	description	green	network_comparison
425	3729.02	saccharomyces cerevisiae nip7p homolog. [refseq;acc:nm_016101]	4301.58	1.15354
426	5942.49	pef protein with a long n-terminal hydrophobic domain (peflin). [refseq;acc:nm_012392]	6853.15	1.15325
427	11736.6	trna (5-methylaminomethyl-2-thiouridylate)-methyltransferase (ec 2.1.1.61). [swissprot;acc:o75648]	13531.9	1.15297
428	3721.19	nucleolar gtp-binding protein 1 (chronic renal failure gene protein) (gtp-binding protein ngb). [swissprot;acc:q9bze4]	4288.17	1.15237
429	6272.91	vinexin (sh3-containing adaptor molecule-1) (scam-1). [swissprot;acc:o60504]	7226.06	1.15195
430	3804.09	transcription factor dp-2 (e2f dimerization partner 2). [swissprot;acc:q14188]	4379.37	1.15123
431	3849.94	dead (asp-glu-ala-asp) box polypeptide 31 isoform 1; dead/dexh helicase ddx31. [refseq;acc:nm_022779]	4431.36	1.15102
432	5244.71	mitochondrial processing peptidase beta subunit, mitochondrial precursor (ec 3.4.24.64) (beta-mpp) (p-52). [swissprot;acc:o75439]	6036.27	1.15093
433	5244.88	mitochondrial processing peptidase alpha subunit, mitochondrial precursor (ec 3.4.24.64) (alpha-mpp) (p-55) (ha1523). [swissprot;acc:q10713]	6036.38	1.15091
434	5246.38	ubiquinol-cytochrome c reductase complex core protein i, mitochondrial precursor (ec 1.10.2.2). [swissprot;acc:p31930]	6037.37	1.15077
435	5233.86	proline synthetase co-transcribed bacterial homolog protein. [swissprot;acc:o94903]	6022.6	1.1507
436	6230.94	arg/abl-interacting protein 2 isoform 2; arg binding protein 2. [refseq;acc:nm_021069]	7168.2	1.15042
437	3779.92	suppressor of swi4 1 homolog (ssf-1) (peter pan homolog). [swissprot;acc:q9nq55]	4348.48
438	6252.58	swi/snf-related, matrix-associated, actin-dependent regulator of chromatin subfamily f member 1 (swi-snf complex protein p270) (b120). [swissprot;acc:o14497]	7192.88	1.15039
439		programmed cell death protein 6 (probable calcium-binding protein alg- 2). [swissprot;acc:o75340]
440	6251.91	calcium-dependent protease, small subunit (calpain regulatory subunit) (calcium-activated neutral proteinase) (canp). [swissprot;acc:p04632]	7192.08	1.15038
441	6251.96	grancalcin. [swissprot;acc:p28676]	7192.13
442	6251.99	sorcin (22 kda protein) (cp-22) (v19). [swissprot;acc:p30626]	7192.17
443	6252.27	brg1-binding protein eld/osa1; eld (eyelid)/osa protein. [refseq;acc:nm_020732]	7192.51
444	3758.67	probable rrna processing protein ebp2 (ebna1 binding protein 2) (nucleolar protein p40). [swissprot;acc:q99848]	4322.87	1.15011
445	3753.71	ad24 protein. [refseq;acc:nm_022451]	4315.95	1.14978
446	3766.03	nucleostemin; putative nucleotide binding protein, estradiol-induced. [refseq;acc:nm_014366]	4329.37	1.14958
447	3751.14	pescadillo homolog 1. [swissprot;acc:o00541]	4310.89	1.14922
448	6259.3	ponsin; sh3-domain protein 5 (ponsin). [refseq;acc:nm_015385]	7190.91	1.14884
449	3761.59	wd-repeat protein 12 (ytm1 homolog). [swissprot;acc:q9gzl7]	4319.69	1.14837
450	4889.21	l-myc-1 proto-oncogene protein. [swissprot;acc:p12524]	5610.52	1.14753
451	4889.71	n-myc proto-oncogene protein. [swissprot;acc:p04198]	5610.69	1.14745
452	3760.8	zinc finger-like protein 9. [refseq;acc:nm_033414]	4315.06	1.14738
453		membrane-associated transporter protein (aim-1 protein) (melanoma antigen aim1). [swissprot;acc:q9umx9]
454		guanine nucleotide-binding protein-like 1 (gtp-binding protein hsr1). [swissprot;acc:p36915]
455	4890.51	ga binding protein alpha chain (gabp-alpha subunit) (transcription factor e4tf1-60) (nuclear respiratory factor-2 subunit alpha). [swissprot;acc:q06546]	5610.95	1.14731
456		ga binding protein beta-2 chain (gabp-beta-2 subunit) (transcription factor e4tf1-47) (gapbp-2) (nuclear respiratory factor-2 subunit gamma). [swissprot;acc:q06545]
457		nadh-ubiquinone oxidoreductase 23 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-23kd) (ci-23kd) (tyky subunit). [swissprot;acc:o00217]
458	4890.55	elongation of very long chain fatty acids protein 1 (cgi-88). [swissprot;acc:q9bw60]	5610.96
459	4892.16	myc proto-oncogene protein (c-myc). [swissprot;acc:p01106]	5611.48	1.14704
460	3790.11	nnp-1 protein (novel nuclear protein 1) (nucleolar protein nop52) (nop52) (d21s2056e). [swissprot;acc:p56182]	4346.98	1.14693
461	5986.65	grb2-related adaptor protein. [swissprot;acc:q13588]	6865.68	1.14683
462	11383.2	ret finger protein 2 (leukemia associated protein 5) (b-cell chronic lymphocytic leukemia tumor suppressor leu5) (putative tumor suppressor rfp2) (tripartite motif protein 13). [swissprot;acc:o60858]	9926.61	1.14674
463	3720.18	atp-dependent rna helicase ddx18 (dead-box protein 18) (myc-regulated dead-box protein) (mrdb). [swissprot;acc:q9nvp1]	4264.46	1.1463
464	4858.96	histone acetyltransferase type b subunit 2 (retinoblastoma binding protein p46) (retinoblastoma-binding protein 7) (rbbp-7). [swissprot;acc:q16576]	5568.85	1.1461
465	3847.31	transcription factor e2f1 (e2f-1) (retinoblastoma binding protein 3) (rbbp-3) (prb-binding protein e2f-1) (pbr3) (retinoblastoma-associated protein 1) (rbap-1). [swissprot;acc:q01094]	4409.22	1.14605
466		transcription factor e2f2 (e2f-2). [swissprot;acc:q14209]
467	4864.25	metastasis-associated protein mta1. [swissprot;acc:q13330]	5573.62	1.14583
468	4869.15	chromatin assembly factor 1 subunit c (caf-1 subunit c) (chromatin assembly factor i p48 subunit) (caf-i 48 kda subunit) (caf-ip48) (retinoblastoma binding protein p48) (retinoblastoma-binding protein 4) (rbbp-4) (msi1 protein homolog). [swissprot;acc:q09028]	5578.02	1.14558
469	3831.17	proliferating-cell nucleolar antigen p120 (proliferation-associated nucleolar protein p120). [swissprot;acc:p46087]	4388.74	1.14554
470	3796.24	block of proliferation 1. [swissprot;acc:q14137]	4348.59	1.1455
471	9649.61	mitogen-activated protein kinase 12 (ec 2.7.1.37) (extracellular signal-regulated kinase 6) (erk-6) (erk5) (stress-activated protein kinase-3) (mitogen-activated protein kinase p38 gamma) (map kinase p38 gamma). [swissprot;acc:p53778]	11053.5	1.14549
472		sphingosine kinase 1 (ec 2.7.1.-) (sk 1) (spk 1). [swissprot;acc:q9nya1]
473		udp-n-acetylglucosamine--dolichyl-phosphate n- acetylglucosaminephosphotransferase (ec 2.7.8.15) (gpt) (g1pt) (n-acetylglucosamine-1-phosphate transferase) (glcnac-1-p transferase). [swissprot;acc:q9h3h5]
474		rho-gtpase-activating protein 7 (rho-type gtpase-activating protein 7) (deleted in liver cancer 1 protein) (dlc-1) (hp protein) (star-related lipid transfer protein 12) (stard12) (start domain-containing protein 12). [swissprot;acc:q96qb1]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.