MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Rank	Value Type	Gene	description	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 8289 in total

Value Type  : Measured
Network Comparison Type  : Divided
Filtered  : 1

Rank	description	Interaction Map	red	green	network_comparison
26	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-12 subunit. [swissprot;acc:q9ubi6]	High confidence	1833.01	892.67	2.0534
	sperm associated antigen 7. [refseq;acc:nm_004890]	Low confidence	23318	19280.8	1.20939
27	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	High confidence	1834.33	895.134	2.04922
	protein kinase, interferon-inducible double stranded rna dependent activator; protein activator of the interferon-induced protein kinase. [refseq;acc:nm_003690]	Low confidence	3840.85	4614.87	1.20152
28	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-3 subunit. [swissprot;acc:p29798]	High confidence	1834.36	895.194	2.04912
	tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106]	Low confidence	3098.94	3719.66	1.2003
29	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-8 subunit (gamma-9). [swissprot;acc:q9uk08]	High confidence	1834.52	895.507	2.04858
	tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616]	Low confidence	3121.28	3739.84	1.19818
30	bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]		36474.3	43509.4	1.19288
	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 subunit. [swissprot;acc:p30670]	High confidence	1834.59	895.633	2.04837
31	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-10 subunit. [swissprot;acc:p50151]		1834.63	895.697	2.04827
	vitelliform macular dystrophy 2-like protein 2. [refseq;acc:nm_153274]	Low confidence	36469.3	43503.3	1.19287
32	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	High confidence	1834.73	895.893	2.04793
	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	Low confidence	36360.3	43368.8	1.19275
33	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-11 subunit. [swissprot;acc:p50152]	High confidence	1835.3	896.972	2.04611
	vitelliform macular dystrophy 2-like protein 1. [refseq;acc:nm_017682]	Low confidence	36360.3	43368.8	1.19275
34	guanine nucleotide-binding protein g(y), alpha subunit (alpha-11). [swissprot;acc:p29992]	High confidence	1836.71	907.546	2.02382
	protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8]	Low confidence	5339.5	6352.4	1.1897
35	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]		33111.4	39358.1	1.18866
	guanine nucleotide-binding protein g(q), alpha subunit. [swissprot;acc:p50148]	High confidence	1836.71	907.564	2.02378
36	guanine nucleotide-binding protein g(z), alpha subunit (g(x) alpha chain) (gz-alpha). [swissprot;acc:p19086]		1836.76	907.741	2.02344
	proto-oncogene protein c-fos (cellular oncogene fos) (g0/g1 switch regulatory protein 7). [swissprot;acc:p01100]	Low confidence	6462.09	7593.77	1.17513
37	guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [swissprot;acc:p11488]	High confidence	1836.76	907.763	2.02339
	jun dimerization protein. [refseq;acc:nm_130469]	Low confidence	6462.09	7593.77	1.17513
38	guanine nucleotide-binding protein g(t), alpha-2 subunit (transducin alpha-2 chain). [swissprot;acc:p19087]	High confidence	1836.76	907.774	2.02337
	rab11-family interacting protein 4. [refseq;acc:nm_032932]	Low confidence	7407.56	8696.7	1.17403
39	eferin. [swissprot;acc:o75154]
	guanine nucleotide-binding protein g(i), alpha-2 subunit (adenylate cyclase-inhibiting g alpha protein). [swissprot;acc:p04899]	High confidence	1836.8	907.903	2.02312
40	fos-related antigen 2. [swissprot;acc:p15408]	Low confidence	6480.59	7600.25	1.17277
	guanine nucleotide-binding protein g(i), alpha-1 subunit (adenylate cyclase-inhibiting g alpha protein). [swissprot;acc:p04898]	High confidence	1836.81	907.978	2.02297
41	guanine nucleotide-binding protein g(k), alpha subunit (g(i) alpha-3). [swissprot;acc:p08754]
	protein fosb (g0/g1 switch regulatory protein 3). [swissprot;acc:p53539]	Low confidence	6481.62	7600.61	1.17264
42	fos-related antigen 1 (fra-1). [swissprot;acc:p15407]		6485.05	7601.81	1.17221
	guanine nucleotide-binding protein beta subunit 5 (transducin beta chain 5). [swissprot;acc:o14775]	High confidence	1857.32	958.237	1.93827
43	cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936]	Low confidence	13689.1	11788.6	1.16122
	guanine nucleotide-binding protein g(i)/g(s)/g(t) beta subunit 3 (transducin beta chain 3). [swissprot;acc:p16520]	High confidence	1881.02	1027.36	1.83093
44	guanine nucleotide-binding protein g(i)/g(s)/g(t) beta subunit 1 (transducin beta chain 1). [swissprot;acc:p04901]		1931.34	1057.39	1.82652
	transcription factor jun-d. [swissprot;acc:p17535]	Low confidence	6614.51	7680.25	1.16112
45	guanine nucleotide-binding protein beta subunit 4 (transducin beta chain 4). [swissprot;acc:q9hav0]	High confidence	1926.69	1056.02	1.82448
	transcription factor jun-b. [swissprot;acc:p17275]	Low confidence	6613.42	7678.76	1.16109
46	neurogenic differentiation factor 2 (neurod2). [swissprot;acc:q15784]	High confidence	779.167	1390.33	1.78438
	transcription regulator protein bach1 (btb and cnc homolog 1) (ha2303). [swissprot;acc:o14867]	Low confidence	8313.02	9645.34	1.16027
47	chromodomain helicase-dna-binding protein 3 (chd-3) (mi-2 autoantigen 240 kda protein) (mi2-alpha). [swissprot;acc:q12873]	High confidence	779.167	1390.33	1.78438
	nuclear factor erythroid 2 related factor 2 (nf-e2 related factor 2) (nfe2-related factor 2) (nuclear factor, erythroid derived 2, like 2) (hebp1). [swissprot;acc:q16236]	Low confidence	8313.02	9645.34	1.16027
48	doc-1 related protein (doc-1r). [swissprot;acc:o75956]	High confidence	779.167	1390.33	1.78438
	transcription regulator protein bach2 (btb and cnc homolog 2). [swissprot;acc:q9byv9]	Low confidence	8313.02	9645.34	1.16027
49	microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8]		13470.1	11654.4	1.1558
	neurogenic differentiation factor 6 (neurod6) (my051 protein). [swissprot;acc:q96nk8]	High confidence	779.167	1390.33	1.78438
50	microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492]	Low confidence	13466.8	11652.4	1.15571
	neurogenic differentiation factor 1 (neurod1) (neurod). [swissprot;acc:q13562]	High confidence	779.167	1390.33	1.78438

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.