MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Filtered	Value Type	Gene	Network Comparison Type	red	Rank	Interaction Map	green	network_comparison	description

Results: HTML CSV LaTeX

Showing element 551 to 600 of 19268 in total

Filtered  : 0
Value Type  : Ranked
Network Comparison Type  : Divided

red	Rank	Interaction Map	green	network_comparison	description
10680.4	633	Low confidence	10983.9	1.02842	survival motor neuron protein (component of gems 1) (gemin1). [swissprot;acc:q16637]
	810		10637.6	1.00402	60s ribosomal protein l10a (csa-19). [swissprot;acc:p53025]
10686	285	High confidence	9925.58	1.07661	dj408b20.3 (novel protein similar to 60s acidic ribosomal protein p2 (rplp2)). [sptrembl;acc:q9h5a9]
10693.9	329	Low confidence	11839.1	1.10709	dimethylaniline monooxygenase [n-oxide forming] 3 (ec 1.14.13.8) (hepatic flavin-containing monooxygenase 3) (fmo 3) (dimethylaniline oxidase 3) (fmo form 2) (fmo ii). [swissprot;acc:p31513]
10694.8	524		11262.9	1.05312	40s ribosomal protein s26. [swissprot;acc:p02383]
10696.7	711		10513.7	1.01741	60s ribosomal protein l7. [swissprot;acc:p18124]
10720.7	142		12382.9	1.15505	zinc finger protein 183-like 1. [refseq;acc:nm_178861]
10720.9	545		11239.5	1.04837	brain protein 16. [refseq;acc:nm_016458]
10721.7	501		11352.1	1.0588	3-hydroxyisobutyryl-coenzyme a hydrolase. [refseq;acc:nm_014362]
10735.1	270	High confidence	9891.37	1.0853	ethanolamine-phosphate cytidylyltransferase (ec 2.7.7.14) (phosphorylethanolamine transferase) (ctp:phosphoethanolamine cytidylyltransferase). [swissprot;acc:q99447]
	271				myosin light chain 1, embryonic muscle/atrial isoform (pro1957). [swissprot;acc:p12829]
10736.2	653	Low confidence	10485.5	1.02391	similar to ribosomal protein, large, p0. [sptrembl;acc:q96fq9]
10741.6	276	High confidence	9922.33	1.08257	60s ribosomal protein l9. [swissprot;acc:p32969]
10749.1	669	Low confidence	10515.3	1.02223	block 23. [sptrembl;acc:q8nhw5]
10750	381		11678.8	1.0864	dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2]
10751	78		13236	1.23114	histone-lysine n-methyltransferase, h3 lysine-79 specific (ec 2.1.1.43) (histone h3-k79 methyltransferase) (h3-k79-hmtase) (dot1-like protein). [swissprot;acc:q8tek3]
10760	709		10573	1.01769	sodium/hydrogen exchanger 6 (na(+)/h(+) exchanger 6) (nhe-6). [swissprot;acc:q92581]
10767.1	777		10855.5	1.00821	filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]
10768.5	316	High confidence	11444	1.06273	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]
10771.7	148	Low confidence	9368.39	1.14979	dj681n20.2 (novel protein similar to ferritin, light polypeptide (ftl)). [sptrembl;acc:q9byw6]
10775.5	788		10700.6	1.007	galectin-4 (lactose-binding lectin 4) (l-36 lactose binding protein) (l36lbp) (antigen ny-co-27). [swissprot;acc:p56470]
10783	275	High confidence	11674.1	1.08264	cleavage and polyadenylation specificity factor, 160 kda subunit (cpsf 160 kda subunit). [swissprot;acc:q10570]
10793.5	67		14291.5	1.32408	presenilin enhancer 2; hematopoietic stem/progenitor cells protein mds033. [refseq;acc:nm_172341]
10808.3	729	Low confidence	10653.8	1.0145	40s ribosomal protein s29. [swissprot;acc:p30054]
10819.8	713		10636	1.01728	dyskerin (nucleolar protein nap57) (cbf5 homolog). [swissprot;acc:o60832]
10831.3	765		10928.4	1.00896	limbic system-associated membrane protein precursor (lsamp). [swissprot;acc:q13449]
10833.3	384	High confidence	11244.5	1.03796	bystin. [swissprot;acc:q13895]
10836.1	664	Low confidence	10593.8	1.02287	60s ribosomal protein l9. [swissprot;acc:p32969]
10844	276		9553.77	1.13505	u2 small nuclear ribonucleoprotein auxiliary factor 35 kda subunit related-protein 1. [swissprot;acc:q15695]
10851	580		11301.8	1.04154	60s acidic ribosomal protein p1. [swissprot;acc:p05386]
10854.8	417	High confidence	10537.9	1.03007	limbic system-associated membrane protein precursor (lsamp). [swissprot;acc:q13449]
10865	745	Low confidence	10994.9	1.01196	eukaryotic initiation factor 4a-like nuk-34. [swissprot;acc:p38919]
10871	682		11087.2	1.01989	histone h1.4 (histone h1b). [swissprot;acc:p10412]
10878.1	636		10584	1.02779	adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]
10878.7	503		11516.1	1.05859	neurofibromin (neurofibromatosis-related protein nf-1) [contains: neurofibromin truncated]. [swissprot;acc:p21359]
10881.2	606		11258.1	1.03464	ubiquinol-cytochrome c reductase complex core protein i, mitochondrial precursor (ec 1.10.2.2). [swissprot;acc:p31930]
10883	154	High confidence	12622.8	1.15986	myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1]
10885.2	621	Low confidence	11216.4	1.03043	crooked neck-like protein 1 (crooked neck homolog) (hcrn) (cgi-201) (mstp021). [swissprot;acc:q9bzj0]
10889.4	5		19873	1.82499	ubiquitously transcribed y chromosome tetratricopeptide repeat protein (ubiquitously transcribed tpr protein on the y chromosome). [swissprot;acc:o14607]
10897	328	High confidence	11520	1.05717	putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37]
10899.4	229		9878.1	1.10339	poly (adp-ribose) glycohydrolase. [refseq;acc:nm_003631]
10899.5	193		12217.4	1.12091	transcription factor iiia (factor a) (tfiiia). [swissprot;acc:q92664]
10900	642	Low confidence	10624.5	1.02593	dj153g14.2 (possible ca binding protein similar to nefa) (fragment). [sptrembl;acc:q9ujn8]
10904.8	431		11727.1	1.07541	butyrate-induced transcript 1. [refseq;acc:nm_016395]
10911.1	382		11853.8	1.0864	far upstream element-binding protein; far upstream element binding protein; fuse-binding protein. [refseq;acc:nm_003902]
10922.9	291	High confidence	11731.8	1.07406
10929	486	Low confidence	11592.3	1.06069	pyrroline-5-carboxylate reductase (ec 1.5.1.2) (p5cr) (p5c reductase). [swissprot;acc:p32322]
10935	145		12622.6	1.15433	metaxin 1. [swissprot;acc:q13505]
10952.3	330		12125.1	1.10708	glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]
10962.4	564		11452	1.04466	60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.