MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Value Type	Filtered	green	Interaction Map	Gene	Rank	description	network_comparison	Network Comparison Type	red

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Value Type  : Measured
Filtered  : 0

green	Interaction Map	Rank	description	network_comparison	Network Comparison Type	red
322.947	Low confidence	148	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]	1.26947	Divided	409.972
		469		87.025	Subtracted
323.433		150	williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]	1.26852	Divided	410.28
		470		86.847	Subtracted
323.685		151	williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]	1.26808	Divided	410.457
		471		86.772	Subtracted
327.517	High confidence	55	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]	1.92644	Divided	630.942
		103		303.425	Subtracted
330.189		54	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	1.93484	Divided	638.862
		101		308.673	Subtracted
335		133	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]	1.32937	Divided	252
		314		83	Subtracted
336.584		157	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	1.28908	Divided	261.105
		319		75.479	Subtracted
	Low confidence	143		1.28908	Divided
		497		75.479	Subtracted
339.154	High confidence	207	cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]	1.19069	Divided	403.827
		331		64.673	Subtracted
339.779	Low confidence	485	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	1.06422	Divided	361.601
		733		21.822	Subtracted
346.751	High confidence	134	mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362]	1.32862	Divided	260.986
		309		85.765	Subtracted
351.772		68	protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981]	1.76802	Divided	198.964
		209		152.808	Subtracted
352.75		71	ubiquitin protein ligase. [refseq;acc:nm_130466]	1.75762	Divided	620
		119		267.25	Subtracted
354.349	Low confidence	318	poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366]	1.16138	Divided	305.111
		599		49.238	Subtracted
359.631	High confidence	120	signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556]	1.37479	Divided	494.417
		238		134.786	Subtracted
359.98		382	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	1.04852	Divided	377.445
		433		17.465	Subtracted
362.023		383	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	1.04825	Divided	379.489
		432		17.466	Subtracted
362.955	Low confidence	101	60s ribosomal protein l37a. [swissprot;acc:p12751]	1.47569	Divided	535.61
		301		172.655	Subtracted
363	High confidence	203	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]	1.19408	Divided	304
		343		59	Subtracted
	Low confidence	296		1.19408	Divided
		555		59	Subtracted
368.317	High confidence	229	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]	1.14829	Divided	320.752
		370		47.565	Subtracted
369.011		227	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]	1.14972	Divided	424.258
		349		55.247	Subtracted
372.961		145	likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033]	1.29544	Divided	287.903
		312		85.058	Subtracted
375.343	Low confidence	179	alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]	1.21433	Divided	455.789
		481		80.446	Subtracted
377.574	High confidence	146	cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2]	1.29466	Divided	291.639
		308		85.935	Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.