MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Rank	Gene	Value Type	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1001 to 1050 of 3228 in total

Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

description	Rank	red	network_comparison	green
eyes absent homolog 2. [swissprot;acc:o00167]	2299	5786.15	1.04572	6050.71
eyes absent homolog 3. [swissprot;acc:q99504]	2274	5779.66	1.04587	6044.78
eyes absent homolog 4. [swissprot;acc:o95677]	2296	5784.9	1.04582	6049.99
ezrin-binding partner pace-1 isoform 1. [refseq;acc:nm_020423]	3228	0.00001	1	0.00001
f-actin capping protein alpha-1 subunit (capz alpha-1). [swissprot;acc:p52907]	1490	6340.5	1.0749	6815.41
f-actin capping protein alpha-2 subunit (capz alpha-2). [swissprot;acc:p47755]	1497	6339.08	1.07467	6812.45
f-actin capping protein alpha-3 subunit (capz alpha-3) (germ cell- specific protein 3). [swissprot;acc:q96kx2]	1681	6304.74	1.06914	6740.66
f-actin capping protein beta subunit (capz beta). [swissprot;acc:p47756]	1682
f-box protein fbw7 isoform 2; archipelago, drosophila, homolog of; f-box protein fbw7; f-box protein sel-10; homolog of c elegans sel-10. [refseq;acc:nm_018315]	100	2353.63	1.3705	3225.65
fad synthetase. [refseq;acc:nm_025207]	1841	3591.95	1.06417	3375.34
far upstream element-binding protein; far upstream element binding protein; fuse-binding protein. [refseq;acc:nm_003902]	2092	5817.41	1.05525	6138.8
farnesyl pyrophosphate synthetase (fpp synthetase) (fps) (farnesyl diphosphate synthetase) [includes: dimethylallyltransferase (ec 2.5.1.1); geranyltranstransferase (ec 2.5.1.10)]. [swissprot;acc:p14324]	1180	4392.63	1.08732	4776.19
fas apoptotic inhibitory molecule. [refseq;acc:nm_018147]	2307	5666.91	1.04528	5923.48
fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402]	2370	5265.95	1.04298	5492.28
fatty acid desaturase 2; linoleoyl-coa desaturase (delta-6-desaturase)-like 2; delta-6 fatty acid desaturase. [refseq;acc:nm_004265]	2369
fatty acid desaturase 3; linoleoyl-coa desaturase (delta-6-desaturase)-like 3; delta-6 fatty acid desaturase. [refseq;acc:nm_021727]	2367
fatty acid hydroxylase domain containing 1. [refseq;acc:nm_024306]	2204	5076.73	1.04916	5326.29
fatty acid-binding protein, adipocyte (afabp) (adipocyte lipid-binding protein) (albp) (a-fabp). [swissprot;acc:p15090]	1665	5791.14	1.0694	6193.02
fatty acid-binding protein, brain (b-fabp) (brain lipid-binding protein) (blbp) (mammary derived growth inhibitor related). [swissprot;acc:o15540]	1667
fatty acid-binding protein, epidermal (e-fabp) (psoriasis-associated fatty acid-binding protein homolog) (pa-fabp). [swissprot;acc:q01469]	1666
fatty acid-binding protein, heart (h-fabp) (muscle fatty acid-binding protein) (m-fabp) (mammary-derived growth inhibitor) (mdgi). [swissprot;acc:p05413]	1674
fatty aldehyde dehydrogenase (ec 1.2.1.3) (aldehyde dehydrogenase, microsomal) (aldh class 3). [swissprot;acc:p51648]	3181	0.00001	1	0.00001
fatty-acid amide hydrolase (ec 3.1.-.-) (oleamide hydrolase) (anandamide amidohydrolase). [swissprot;acc:o00519]	1951	5888.32	1.06073	6245.89
fem-1 homolog b; fem-1-like death receptor binding protein; fem-1 (c.elegans) homolog b. [refseq;acc:nm_015322]	403	5201.41	1.16109	4479.76
ferritin heavy chain (ferritin h subunit). [swissprot;acc:p02794]	620	6227.87	1.12605	7012.9
ferritin heavy polypeptide-like 17. [swissprot;acc:q9bxu8]	635	6228.97	1.12595	7013.53
ferritin light chain (ferritin l subunit). [swissprot;acc:p02792]	633	6228.39	1.126	7013.19
ferrochelatase, mitochondrial precursor (ec 4.99.1.1) (protoheme ferro-lyase) (heme synthetase). [swissprot;acc:p22830]	3185	0.00001	1	0.00001
fetal brain protein 239 (239fb). [swissprot;acc:q15777]	1053	4757.46	1.09279	5198.91
fibrillarin (34 kda nucleolar scleroderma antigen). [swissprot;acc:p22087]	646	4019.88	1.12506	4522.61
fibrillin 1 precursor. [swissprot;acc:p35555]	2844	0.00001	1	0.00001
fibrillin 2 precursor. [swissprot;acc:p35556]	2955
fibrillin 3. [refseq;acc:nm_032447]	2939
fibulin-1 precursor. [swissprot;acc:p23142]	1304	8550.79	1.08154	9248.06
fibulin-2 precursor. [swissprot;acc:p98095]	1216	8670.59	1.08561	9412.9
ficolin 2 precursor (collagen/fibrinogen domain-containing protein 2) (ficolin-b) (ficolin b) (serum lectin p35) (ebp-37) (hucolin) (l- ficolin). [swissprot;acc:q15485]	21	677.5	2.75351	1865.5
fidgetin-like 1. [refseq;acc:nm_022116]	1491	6057.46	1.07486	6510.9
filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]	113	4366.44	1.35116	5899.76
filamin b, beta (actin binding protein 278); beta filamin; filamin 1 (actin-binding protein-280)-like; filamin b, beta (actin-binding protein-278); filamin b, beta. [refseq;acc:nm_001457]	108
fip1-like 1; rearranged in hypereosinophilia. [refseq;acc:nm_030917]	270	23640.2	1.21358	19479.8
fk506-binding protein 1a (ec 5.2.1.8) (peptidyl-prolyl cis-trans isomerase) (ppiase) (rotamase) (12 kda fkbp) (fkbp-12) (immunophilin fkbp12). [swissprot;acc:p20071]	1207	5946.33	1.08635	6459.79
flap endonuclease-1 (ec 3.-.-.-) (maturation factor 1) (mf1). [swissprot;acc:p39748]	2831	0.00001	1	0.00001
flavoprotein oxidoreductase mical2. [refseq;acc:nm_014632]	556	6167.93	1.13615	7007.7
flotillin-1. [swissprot;acc:o75955]	1296	5655.85	1.08218	6120.64
folylpolyglutamate synthase, mitochondrial precursor (ec 6.3.2.17) (folylpoly-gamma-glutamate synthetase) (fpgs). [swissprot;acc:q05932]	2009	4934.48	1.05861	5223.69
forkhead box p4; fork head-related protein like a; winged-helix repressor foxp4. [refseq;acc:nm_138457]	130	2234.68	1.33287	2978.53
forkhead box protein g1c (forkhead-related protein fkhl3) (hfk3) (fragment). [swissprot;acc:q14488]	578	6739.81	1.13425	7644.62
forkhead box protein p1 (hspc215). [swissprot;acc:q9h334]	131	2234.73	1.33285	2978.57
forkhead box protein p3 (zinc finger protein jm2) (scurfin). [swissprot;acc:q9bzs1]	132	2236.61	1.33253	2980.35
formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	93	4245.52	1.39977	5942.75

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.