MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 151 to 200 of 3228 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	description	network_comparison	red	green
151	myosin vc (myosin 5c). [swissprot;acc:q9nqx4]	1.19565	55	46
152	myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1]
153	chromosome 3p21.1 gene sequence. [refseq;acc:nm_013286]	1.19466	249.663	298.263
154	regulator of g-protein signaling 19 (rgs19) (g-alpha interacting protein) (gaip protein). [swissprot;acc:p49795]
155	putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37]
156	regulator of g-protein signaling 20 (rgs20) (regulator of gz- selective protein signaling 1) (gz-selective gtpase-activating protein) (g(z)gap). [swissprot;acc:o76081]
157	transcription factor lbx1. [swissprot;acc:p52954]
158	mosaic protein lgn. [swissprot;acc:p81274]
159	regulator of g-protein signaling 17 (rgs17). [swissprot;acc:q9ugc6]
160	guanine nucleotide-binding protein g(o), alpha subunit 1. [swissprot;acc:p09471]
161	rap1 gtpase-activating protein 1 (rap1gap). [swissprot;acc:p47736]
162	nostrin. [refseq;acc:nm_052946]	1.19058	209.299	249.187
163	eap30 subunit of ell complex. [refseq;acc:nm_007241]
164	liv-1 protein, estrogen regulated. [refseq;acc:nm_012319]
165	glutamate decarboxylase, 65 kda isoform (ec 4.1.1.15) (gad-65) (65 kda glutamic acid decarboxylase). [swissprot;acc:q05329]
166	gamma-soluble nsf attachment protein (snap-gamma) (n-ethylmaleimide- sensitive factor attachment protein, gamma). [swissprot;acc:q99747]
167	glutamate decarboxylase, 67 kda isoform (ec 4.1.1.15) (gad-67) (67 kda glutamic acid decarboxylase). [swissprot;acc:q99259]
168	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]	1.18722	82.5916	98.0548
169	apg3p; pc3-96 protein. [refseq;acc:nm_022488]
170	nucleolysin tia-1 (rna-binding protein tia-1) (p40-tia-1) [contains: p15-tia-1]. [swissprot;acc:p31483]	1.17894	227.199	192.715
171	nucleolysin tiar (tia-1 related protein). [swissprot;acc:q01085]	1.17829	227.202	192.823
172	cg9578-like; yeast ypr037w and worm c02c2.6 predicted proteins-like. [refseq;acc:nm_152902]	1.17685	174.667	205.556
173	small nuclear ribonucleoprotein sm d1 (snrnp core protein d1) (sm-d1) (sm-d autoantigen). [swissprot;acc:p13641]	1.17599	227.032	193.056
174	dgcr14 protein (digeorge syndrome critical region 14) (es2 protein). [swissprot;acc:q96df8]	1.17133	335	286
175	cop9 constitutive photomorphogenic homolog subunit 3; cop9 complex subunit 3; jab1-containing signalosome subunit 3. [refseq;acc:nm_003653]	1.17123	199.949	234.187
176	dna polymerase epsilon p12 subunit (dna polymerase epsilon subunit 4). [swissprot;acc:q9nr33]	1.1689	275.754	235.908
177	dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2]	1.1663	229.406	196.695
178	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	1.1652	226.887	194.72
179	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]	1.16476	226.884	194.79
180	tar dna-binding protein-43 (tdp-43). [swissprot;acc:q13148]	1.16474	256.228	298.438
181	b9 protein; likely ortholog of mouse endothelial precursor protein b9. [refseq;acc:nm_015681]	1.16294	229.818	267.265
182	histone acetyltransferase type b catalytic subunit (ec 2.3.1.48). [swissprot;acc:o14929]	1.15422	277.546	240.461
183	20 kda nuclear cap binding protein (ncbp 20 kda subunit) (cbp20) (ncbp interacting protein 1) (nip1). [swissprot;acc:p52298]	1.153	228.306	198.011
184	odd-skipped related 1; odz (odd oz/ten-m) related 1. [refseq;acc:nm_145260]	1.15239	274.027	237.79
185	adiponectin receptor 2. [refseq;acc:nm_024551]	1.14292	281.582	246.371
186	filamin b, beta (actin binding protein 278); beta filamin; filamin 1 (actin-binding protein-280)-like; filamin b, beta (actin-binding protein-278); filamin b, beta. [refseq;acc:nm_001457]	1.14179	226.582	198.444
187	rev1-like; rev1 protein; rev1 (yeast homolog)- like. [refseq;acc:nm_016316]
188	protein arginine n-methyltransferase 1 (ec 2.1.1.-) (interferon receptor 1-bound protein 4). [swissprot;acc:q99873]
189	protein arginine n-methyltransferase 4 (ec 2.1.1.-). [swissprot;acc:q9nr22]
190	u1 small nuclear ribonucleoprotein 70 kda (u1 snrnp 70 kda) (snrnp70) (u1-70k). [swissprot;acc:p08621]
191	filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]
192	musashi 2 isoform a. [refseq;acc:nm_138962]	1.14055	227.491	199.458
193	musashi 1. [refseq;acc:nm_002442]
194	nuclear protein ukp68. [refseq;acc:nm_024824]
195	huntingtin interacting protein c. [refseq;acc:nm_012272]	1.13748	227.971	200.417
196	forkhead box p4; fork head-related protein like a; winged-helix repressor foxp4. [refseq;acc:nm_138457]	1.13745	263.215	231.407
197	forkhead box protein p1 (hspc215). [swissprot;acc:q9h334]
198	forkhead box protein p3 (zinc finger protein jm2) (scurfin). [swissprot;acc:q9bzs1]	1.13741	263.191	231.394
199	palmitoyl-protein thioesterase 2 precursor (ec 3.1.2.22) (palmitoyl- protein hydrolase 2) (ppt-2) (g14). [swissprot;acc:q9umr5]	1.13729	242.735	276.059
200	egf-like-domain, multiple 7; neu1 protein. [refseq;acc:nm_016215]	1.1372	242.718	276.018

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.