MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	Rank	Network Comparison Type	red	Value Type	description	Interaction Map	green	Filtered	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 1923 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
network_comparison  : 0

Rank	red	Value Type	description	green	Filtered
493	17901.1	Squared	3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	17901.1	0
494	0	Measured	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	0
		Squared
		Rooted
495		Measured	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
		Squared
		Rooted
496		Measured	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
		Squared
		Rooted
497		Measured	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
		Squared
		Rooted
498		Measured	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
		Squared
		Rooted
499		Measured	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
		Squared
		Rooted
500		Measured	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
		Squared
		Rooted
	394	Ranked	huntingtin interacting protein e; huntingtin interactor protein e. [refseq;acc:nm_007076]	394
501	0	Measured	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	0
		Ranked	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
		Squared	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
		Rooted
502		Measured	brca1 associated protein. [refseq;acc:nm_006768]
		Ranked
		Squared
		Rooted
2756		Measured	3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]		1
		Ranked
		Squared
		Rooted
2757		Measured	nucleosome assembly protein 1-like 1 (nap-1 related protein). [swissprot;acc:p55209]
		Ranked
		Squared
		Rooted
2758		Measured	nucleosome assembly protein 1-like 2 (brain-specific protein, x- linked). [swissprot;acc:q9ulw6]
		Ranked
		Squared
		Rooted
2759		Measured	retinoic acid receptor rxr-alpha. [swissprot;acc:p19793]
		Ranked
		Squared
		Rooted
2760		Measured	t-cell acute lymphocytic leukemia-2 protein (tal-2 protein). [swissprot;acc:q16559]
		Ranked
		Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.