Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Rank Value Type Gene green Interaction Map Filtered Network Comparison Type network_comparison red
Results: HTML CSV LaTeX Showing element 451 to 500 of 66312 in total
Filtered  : 1
description
Rank
Value Type
green
Interaction Map
Network Comparison Type
network_comparison
red
26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998] 2321 Ranked 194.732 Low confidence Divided 1.01866 198.366
2394 219.014 High confidence Subtracted 0.822 218.192
2395 Divided 1.00377
2407 194.732 Low confidence Subtracted 3.634 198.366
4819 Squared 47560.6 398.6 47959.2
4841 Divided 1.00838
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210] 453 53788.1 High confidence Subtracted 5530.3 59318.4
797 44326.9 Low confidence 2208.3 46535.2
864 Divided 1.04982
1637 Ranked 199.408 High confidence 1.01479 202.358
1682 Subtracted 2.95
1721 Squared 53788.1 Divided 1.10282 59318.4
1772 Rooted 76.9113 Subtracted 1.9751 74.9362
2059 Divided 1.02636
2149 Ranked 197.22 Low confidence Subtracted 3.762 200.982
2163 Divided 1.01908
2260 Rooted 74.792 Subtracted 2.4749 72.3171
2297 Divided 1.03422
2602 Measured 9234.09 High confidence Subtracted 83.65 9150.44
2651 Divided 1.00914
2944 8314.51 Low confidence Subtracted 225.57 8088.94
3044 Divided 1.02789
26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524] 1280 Squared 30113.9 High confidence Subtracted 2937.1 27176.8
1577 Measured 6349.04 Divided 1.07181 5923.66
1599 Subtracted 425.38
1630 Squared 30113.9 Divided 1.10807 27176.8
1944 Rooted 64.5421 1.02853 62.7515
1968 Subtracted 1.7906
2478 Ranked 216.801 Divided 1.00289 216.177
2486 Subtracted 0.624
2526 Measured 8326.51 Low confidence 238.39 8088.12
2711 Divided 1.02947
3092 Rooted 74.8438 Subtracted 2.2929 72.5509
3167 Divided 1.0316
3429 Squared 44345.7 Subtracted 1427.9 45773.6
3515 Ranked 197.374 Divided 1.01489 200.312
3521 Subtracted 2.938
3537 Squared 44345.7 Divided 1.0322 45773.6
26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [swissprot;acc:q99460] 830 Ranked 199.229 Subtracted 5.131 204.36
857 Divided 1.02575
1146 Squared 42544.1 1.04611 44506
1162 Rooted 73.5808 1.03812 70.8788
1182 Squared 29969 High confidence Subtracted 3108.3 26860.7
1280 Rooted 73.5808 Low confidence 2.702 70.8788
1379 Squared 42544.1 1961.9 44506
1476 29969 High confidence Divided 1.11572 26860.7
1862 Measured 6195.48 Subtracted 369.48 5826
1883 Divided 1.06342
2129 Rooted 63.5033 1.02418 62.0038
2140 Subtracted 1.4995

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/