MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

network_comparison	Filtered	green	Value Type	description	Interaction Map	Network Comparison Type	Rank	red	Gene

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

network_comparison  : 0
Filtered  : 0
green  : 0
Network Comparison Type  : Subtracted
red  : 0

Value Type	description	Interaction Map	Rank
Measured	brca1 associated protein. [refseq;acc:nm_006768]	High confidence	502
	cobw-like protein. [refseq;acc:nm_018491]	Low confidence	839
	gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]		838
	gamma-glutamyltransferase. [sptrembl;acc:q14390]		841
	gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]		842
	gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]		837
	gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]		843
	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	High confidence	501
	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]		495
	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]		494
	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]		497
	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]		499
	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]		496
	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]		500
	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]		498
		Low confidence	840
Ranked	brca1 associated protein. [refseq;acc:nm_006768]	High confidence	502
	cobw-like protein. [refseq;acc:nm_018491]	Low confidence	839
	gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]		838
	gamma-glutamyltransferase. [sptrembl;acc:q14390]		841
	gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]		842
	gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]		837
	gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]		843
	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	High confidence	501
Squared	brca1 associated protein. [refseq;acc:nm_006768]		502
	cobw-like protein. [refseq;acc:nm_018491]	Low confidence	839
	gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]		838
	gamma-glutamyltransferase. [sptrembl;acc:q14390]		841
	gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]		842
	gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]		837
	gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]		843
	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	High confidence	501
	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]		495
	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]		494
	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]		497
	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]		499
	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]		496
	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]		500
	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]		498
		Low confidence	840
Rooted	brca1 associated protein. [refseq;acc:nm_006768]	High confidence	502
	cobw-like protein. [refseq;acc:nm_018491]	Low confidence	839
	gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]		838
	gamma-glutamyltransferase. [sptrembl;acc:q14390]		841
	gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]		842
	gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]		837
	gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]		843
	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	High confidence	501
	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]		495
	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]		494

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.