Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Value Type Gene green Interaction Map Rank description Network Comparison Type Filtered red network_comparison
Results: HTML CSV LaTeX Showing element 1251 to 1300 of 3228 in total
Value Type  : Measured
Interaction Map  : High confidence
Network Comparison Type  : Divided
Filtered  : 1
green
Rank
description
red
network_comparison
5683 2622 suppressor of actin mutations 2-like isoform b; dj1033b10.5. [refseq;acc:nm_022553] 5599.85 1.01485
5684.97 2496 solute carrier family 35, member b1; udp-galactose transporter related. [refseq;acc:nm_005827] 5534.46 1.0272
5687.2 1072 prefoldin subunit 3 (von hippel-lindau binding protein 1) (vhl binding protein-1) (vbp-1) (hibbj46). [swissprot;acc:q15765] 5207.39 1.09214
1073 prefoldin subunit 2 (hspc231). [swissprot;acc:q9uhv9]
1074 uxt protein (ubiquitously expressed transcript protein) (hspc024). [swissprot;acc:q9ubk9]
5694.55 880 peptide chain release factor 1, mitochondrial precursor (mrf-1). [swissprot;acc:o75570] 5166.04 1.1023
5694.99 96 lag1 longevity assurance homolog 2 isoform 1; l3 pigment; tumor metastasis-suppressor. [refseq;acc:nm_022075] 4110.14 1.3856
5695.44 884 mannose-p-dolichol utilization defect 1 protein (suppressor of lec15 and lec35 glycosylation mutation homolog) (sl15). [swissprot;acc:o75352] 5167.15 1.10224
5696.12 885 mitochondrial translational release factor 1-like. [refseq;acc:nm_019041] 5168.01 1.10219
5704.87 242 max protein. [swissprot;acc:p25912] 4640.26 1.22943
5706.64 2011 hyaluronan synthase 2 (ec 2.4.1.212) (hyaluronate synthase 2) (hyaluronic acid synthase 2) (ha synthase 2). [swissprot;acc:q92819] 5391.27 1.0585
2012 hyaluronan synthase 1 (ec 2.4.1.212) (hyaluronate synthase 1) (hyaluronic acid synthase 1) (ha synthase 1) (huhas1). [swissprot;acc:q92839]
2013 hyaluronan synthase 3 (ec 2.4.1.212) (hyaluronate synthase 3) (hyaluronic acid synthase 3) (ha synthase 3). [swissprot;acc:o00219]
5712.39 2576 protein tara (trio-associated repeat on actin) (hrihfb2122). [swissprot;acc:q9h2d6] 5608.22 1.01857
5712.59 2575 rho interacting protein 3. [refseq;acc:nm_015134] 5608.38 1.01858
5721.43 2394 trifunctional purine biosynthetic protein adenosine-3 [includes: phosphoribosylamine--glycine ligase (ec 6.3.4.13) (gars) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); phosphoribosylformylglycinamidine cyclo-ligase (ec 6.3.3.1) (airs) (phosphoribosyl-aminoimidazole synthetase) (air synthase); phosphoribosylglycinamide formyltransferase (ec 2.1.2.2) (gart) (gar transformylase) (5'-phosphoribosylglycinamide transformylase)]. [swissprot;acc:p22102] 5502.5 1.03979
5723.22 827 transcription factor smif; decapping enzyme hdcp1a. [refseq;acc:nm_018403] 5172.07 1.10656
5730.73 1918 seven in absentia homolog 1. [refseq;acc:nm_003031] 5394.24 1.06238
5733.93 1906 mitochondrial ribosomal protein l18. [refseq;acc:nm_014161] 5396.61 1.06251
5737.17 896 signal recognition particle receptor alpha subunit (sr-alpha) (docking protein alpha) (dp-alpha). [swissprot;acc:p08240] 5208.27 1.10155
5737.79 1900 seven in absentia homolog 2. [refseq;acc:nm_005067] 5399.47 1.06266
5738.73 1705 translation initiation factor eif-2b epsilon subunit (eif-2b gdp-gtp exchange factor). [swissprot;acc:q13144] 5369.43 1.06878
1706 translation initiation factor eif-2b gamma subunit (eif-2b gdp-gtp exchange factor). [swissprot;acc:q9nr50]
5741.63 842 loh1cr12. [refseq;acc:nm_058169] 5195.48 1.10512
843 unr protein. [swissprot;acc:o75534]
5743.5 1796 tubulin tyrosine ligase-like protein hottl (hqp0207). [swissprot;acc:q9y4r7] 5387.64 1.06605
5744.76 1788 arp2/3 complex 16 kda subunit (p16-arc) (actin-related protein 2/3 complex subunit 5). [swissprot;acc:o15511] 5386.49 1.06651
5744.78 1787 interferon-related developmental regulator 2 (skmc15 protein). [swissprot;acc:q12894] 5386.48 1.06652
5744.89 1774 dj470l14.3 (novel protein similar to the arp2/3 protein complex subunit p21-arc (arc21)). [sptrembl;acc:q9h5b6] 5386.37 1.06656
1775 zinc finger protein 258. [refseq;acc:nm_145310]
1776 zinc finger protein 261 (dxs6673e protein). [swissprot;acc:q14202]
1777 zinc finger protein 262; cell death inhibiting rna. [refseq;acc:nm_005095]
1778 actin-like protein 2 (actin-related protein 2). [swissprot;acc:o15142]
1779 conserved oligomeric golgi complex component 3 (vesicle docking protein sec34 homolog) (p94). [swissprot;acc:q96jb2]
1780 similar to actin-related protein 3-beta. [sptrembl;acc:q96bt2]
1781 arp2/3 complex 41 kda subunit (p41-arc) (actin-related protein 2/3 complex subunit 1b). [swissprot;acc:o15143]
1782 zinc finger protein 198 (fused in myeloproliferative disorders protein) (rearranged in atypical myeloproliferative disorder protein). [swissprot;acc:q9ubw7]
1783 actin-like protein 3 (actin-related protein 3) (actin-2). [swissprot;acc:p32391]
1784 arp2/3 complex 21 kda subunit (p21-arc) (actin-related protein 2/3 complex subunit 3). [swissprot;acc:o15145]
1785 nardilysin precursor (ec 3.4.24.61) (n-arginine dibasic convertase) (nrd convertase) (nrd-c). [swissprot;acc:o43847]
1786 actin-related protein 2/3 complex subunit 1a (sop2-like protein). [swissprot;acc:q92747]
5746.51 1750 arp2/3 complex 34 kda subunit (p34-arc) (actin-related protein 2/3 complex subunit 2). [swissprot;acc:o15144] 5384.89 1.06715
5749.33 856 heparin sulfate n-deacetylase/n-sulfotransferase (ec 2.8.2.-) (n- hsst) (n-heparin sulfate sulfotransferase) (glucosaminyl n- deacetylase/n-sulfotransferase). [swissprot;acc:p52849] 5210.58 1.1034
857 n-deacetylase/n-sulfotransferase (heparan glucosaminyl) 3. [refseq;acc:nm_004784]
858 n-deacetylase/n-sulfotransferase 4. [refseq;acc:nm_022569]
859 heparan sulfate n-deacetylase/n-sulfotransferase (ec 2.8.2.8) (n-hsst) (hsnst) ([heparan sulfate]-glucosamine n-sulfotransferase) (n-heparan sulfate sulfotransferase) (glucosaminyl n-deacetylase/n- sulfotransferase). [swissprot;acc:p52848]
860 protein cdc27hs (cell division cycle protein 27 homolog) (h-nuc). [swissprot;acc:p30260]
5749.69 1991 solute carrier family 2, facilitated glucose transporter, member 6 (glucose transporter type 6) (glucose transporter type 9). [swissprot;acc:q9ugq3] 5429.27 1.05902
1992 solute carrier family 2, facilitated glucose transporter, member 8 (glucose transporter type 8) (glucose transporter type x1). [swissprot;acc:q9ny64]
5750.34 826 exportin 1; exportin-1 (required for chromosome region maintenance); exportin 1 (crm1, yeast, homolog); crm1, yeast, homolog. [refseq;acc:nm_003400] 5195.58 1.10678

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/