MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Filtered	Interaction Map	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 51 to 100 of 14920 in total

Network Comparison Type  : Divided
Interaction Map  : High confidence

Rank	description	Value Type	Filtered	red	network_comparison	green
7	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]	Squared	0	0.00001	187479	1.87479
		Rooted			943398	9.43398
	sedlin. [swissprot;acc:o14582]	Measured			4300000	43
	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [swissprot;acc:o60906]		1	1153.5	3.39764	339.5
		Squared		314.926	11.544	27.2805
		Rooted		33.9632	1.84327	18.4255
8	db83 protein. [swissprot;acc:p57088]	Measured		1153.5	3.39764	339.5
		Squared		314.926	11.544	27.2805
		Rooted		33.9632	1.84327	18.4255
	ero1-like. [refseq;acc:nm_014584]	Squared	0	1.59148	159148	0.00001
		Rooted		9.05539	905539
	hbs1-like. [refseq;acc:nm_006620]	Ranked	1	215	1.49767	322
	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]		0	11525	1.89918	21888
	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]	Measured		0.00001	4300000	43
9	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]			85	75.4118	6410
	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]	Squared		0.852071	85207.1	0.00001
		Rooted		7.74597	774597
	tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106]	Measured	1	398.5	3.21581	1281.5
		Squared		37.5863	10.3414	388.696
		Rooted		19.9625	1.79326	35.798
	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]	Ranked	0	11525	1.89918	21888
	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266]		1	212	1.45755	309
10	fructose-1,6-bisphosphatase isozyme 2 (ec 3.1.3.11) (d-fructose-1,6- bisphosphate 1-phosphohydrolase) (fbpase). [swissprot;acc:o00757]		0	7509.39	1.88805	14178.1
	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]	Squared		0.00001	82390.5	0.823905
		Rooted			768115	7.68115
	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]	Measured		85	75.4118	6410
	protein x 0004. [refseq;acc:nm_016301]	Ranked	1	212	1.45755	309
	tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616]	Measured		398.5	3.21581	1281.5
		Squared		37.5863	10.3414	388.696
		Rooted		19.9625	1.79326	35.798
11	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552]	Measured		398.5	3.21581	1281.5
		Squared		37.5863	10.3414	388.696
		Rooted		19.9625	1.79326	35.798
	potential phospholipid-transporting atpase iia (ec 3.6.1.-). [swissprot;acc:o75110]	Ranked	0	11627	1.86092	6248
	rad50-interacting protein 1. [refseq;acc:nm_021930]		1	337	1.45259	232
	sedlin. [swissprot;acc:o14582]	Squared	0	0.00001	43763.3	0.437633
		Rooted			655744	6.55744
	serpin b12. [swissprot;acc:q96p63]	Measured		199.549	35.8425	5.56738
12	cytoplasmic polyadenylation element binding protein 4. [refseq;acc:nm_030627]		1	398.5	3.21581	1281.5
		Squared		37.5863	10.3414	388.696
		Rooted		19.9625	1.79326	35.798
	folylpolyglutamate synthase, mitochondrial precursor (ec 6.3.2.17) (folylpoly-gamma-glutamate synthetase) (fpgs). [swissprot;acc:q05932]	Ranked	0	9429.18	1.81023	5208.84
	hurpin (hacat uv-repressible serpin) (protease inhibitor 13) (headpin) (serpin b13). [swissprot;acc:q9uiv8]	Measured		199.249	34.8539	5.71669
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Ranked	1	337	1.45259	232
	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]	Squared	0	0.00001	43763.3	0.437633
		Rooted			655744	6.55744
13	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	Measured		1363	29	47
	cytoplasmic polyadenylation element binding protein 3. [refseq;acc:nm_014912]		1	398.5	3.21581	1281.5
		Squared		37.5863	10.3414	388.696
		Rooted		19.9625	1.79326	35.798

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.