MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	red	Interaction Map	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 66312 in total

Filtered  : 1

Rank	description	Value Type	Network Comparison Type	red	Interaction Map	green	network_comparison
4	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	Ranked	Divided	15	High confidence	28	1.86667
		Squared	Subtracted	407289		263351	143938
	cytohesin 4. [swissprot;acc:q9uia0]	Measured		41482.5		33356.5	8126
	hbs1-like. [refseq;acc:nm_006620]		Divided	2597.5		698.5	3.71868
		Squared		1596.92		115.48	13.8285
		Rooted		50.9657		26.4292	1.92839
			Subtracted				24.5365
	lysosome-associated membrane glycoprotein 2 precursor (lamp-2) (cd107b antigen). [swissprot;acc:p13473]	Measured	Divided	2399.5	Low confidence	543.5	4.4149
		Ranked	Subtracted	223		330	107
		Squared	Divided	1362.75		69.9153	19.4914
		Rooted		48.9847		23.3131	2.10117
			Subtracted				25.6716
	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	Squared		332411		473408	140997
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Ranked		337	High confidence	232	105
5	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	Rooted		145.551		168.796	23.245
	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]			202.235	Low confidence	178.965	23.27
	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	Measured		41482.5	High confidence	33356.5	8126
	cytohesin 4. [swissprot;acc:q9uia0]	Ranked	Divided	15		28	1.86667
		Squared	Subtracted	407289		263351	143938
	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	Measured	Divided	1153.5		339.5	3.39764
		Squared		314.926		27.2805	11.544
		Rooted		33.9632		18.4255	1.84327
	lysosome-associated membrane glycoprotein 2 precursor (lamp-2) (cd107b antigen). [swissprot;acc:p13473]	Ranked		223	Low confidence	330	1.47982
	oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]	Measured		736.5		2113.5	2.86965
		Ranked	Subtracted	318		240	78
		Squared	Divided	128.386		1057.25	8.23493
		Rooted		27.1385		45.9728	1.69401
	vitelliform macular dystrophy 2-like protein 1. [refseq;acc:nm_017682]	Squared	Subtracted	332411		473408	140997
	vitelliform macular dystrophy 2-like protein 2. [refseq;acc:nm_153274]	Measured		36469.3		43503.3	7034
	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266]	Ranked		212	High confidence	309	97
6	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	Rooted		145.551	Low confidence	168.796	23.245
	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	Ranked	Divided	15	High confidence	28	1.86667
		Squared	Subtracted	407289		263351	143938
	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]			299771	Low confidence	424645	124874
	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	Measured	Divided	1153.5	High confidence	339.5	3.39764
		Squared		314.926		27.2805	11.544
		Rooted		33.9632		18.4255	1.84327
	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	Measured	Subtracted	36360.3	Low confidence	43368.8	7008.5
	oxysterol binding protein-related protein 3 (osbp-related protein 3) (orp-3). [swissprot;acc:q9h4l5]		Divided	736.5		2113.5	2.86965
		Ranked	Subtracted	318		240	78
		Squared	Divided	128.386		1057.25	8.23493
		Rooted		27.1385		45.9728	1.69401
	oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]	Ranked		318		240	1.325
	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]	Rooted	Subtracted	145.551	High confidence	168.796	23.245
	protein x 0004. [refseq;acc:nm_016301]	Ranked		212		309	97
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Measured		44490.5		36927.5	7563
7	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]			21185		28492	7307
		Squared		106226	Low confidence	192141	85915
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Ranked	Divided	215	High confidence	322	1.49767
	mitochondrial solute carrier protein. [refseq;acc:nm_145305]	Rooted	Subtracted	145.551	Low confidence	168.796	23.245

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.