Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Value Type green Interaction Map Gene Rank description Filtered Network Comparison Type red network_comparison
Results: HTML CSV LaTeX Showing element 644 to 693 of 3228 in total
Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1
Network Comparison Type  : Divided
green
Rank
description
red
network_comparison
3504.91 2242 40s ribosomal protein s2 (s4) (llrep3 protein). [swissprot;acc:p15880] 3670.45 1.04723
3508.13 2235 40s ribosomal protein s3. [swissprot;acc:p23396] 3674.29 1.04736
3516.98 2343 40s ribosomal protein s5. [swissprot;acc:p46782] 3672.17 1.04413
3520.86 2374 dna-directed rna polymerase iii largest subunit (ec 2.7.7.6) (rpc155) (rpc1). [swissprot;acc:o14802] 3669.57 1.04224
3521.41 2381 dna-directed rna polymerase i largest subunit (ec 2.7.7.6) (rna polymerase i 194 kda subunit) (rpa194). [swissprot;acc:o95602] 3667.94 1.04161
3526.65 2372 60s ribosomal protein l12, mitochondrial precursor (l12mt) (5c5-2). [swissprot;acc:p52815] 3677.53 1.04278
2373 nudix (nucleoside diphosphate linked moiety x)-type motif 12. [refseq;acc:nm_031438]
3529.35 2386 60s ribosomal protein l30. [swissprot;acc:p04645] 3674.02 1.04099
3531.96 2491 hepatocyte nuclear factor 4-gamma (hnf-4-gamma). [swissprot;acc:q14541] 3436.65 1.02773
2492 growth arrest and dna-damage-inducible protein gadd45 gamma (cytokine responsive protein cr6). [swissprot;acc:o95257]
2493 growth arrest and dna-damage-inducible protein gadd45 alpha (dna- damage inducible transcript 1) (ddit1). [swissprot;acc:p24522]
2494 hepatocyte nuclear factor 4-alpha (hnf-4-alpha) (transcription factor hnf-4) (transcription factor 14). [swissprot;acc:p41235]
2495 growth arrest and dna-damage-inducible protein gadd45 beta (negative growth-regulatory protein myd118) (myeloid differentiation primary response protein myd118). [swissprot;acc:o75293]
3543.33 2380 suppressor of ty 5 homolog; suppressor of ty (s.cerevisiae) 5 homolog. [refseq;acc:nm_003169] 3690.79 1.04162
3569.68 2385 adenylate kinase isoenzyme 2, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p54819] 3716.43 1.04111
3580.35 2225 60s ribosomal protein l9. [swissprot;acc:p32969] 3750.99 1.04766
3584.47 2436 40s ribosomal protein s14 (pro2640). [swissprot;acc:p06366] 3708.67 1.03465
2437 40s ribosomal protein s18 (ke-3) (ke3). [swissprot;acc:p25232]
3611.05 2447 60s ribosomal protein l13, mitochondrial (l13mt). [swissprot;acc:q9byd1] 3730.53 1.03309
2448 40s ribosomal protein s16. [swissprot;acc:p17008]
3611.45 2449 60s ribosomal protein l13a (23 kda highly basic protein). [swissprot;acc:p40429] 3730.74 1.03303
3629.51 2439 putative eukaryotic translation initiation factor 1a (eif-1a) (eif- 4c). [swissprot;acc:o75642] 3754.39 1.03441
3652.28 2321 dna polymerase epsilon p17 subunit (dna polymerase epsilon subunit 3) (chromatin accessibility complex 17) (huchrac17) (chrac-17). [swissprot;acc:q9nrf9] 3496.21 1.04464
3675.65 2485 zinc finger protein 174 (aw-1). [swissprot;acc:q15697] 3568.18 1.03012
3675.97 2484 zinc finger imprinted 2. [swissprot;acc:q9nzv7] 3568.45 1.03013
3676.38 2483 zinc finger protein 18 (zinc finger protein kox11) (fragment). [swissprot;acc:p17022] 3568.8 1.03014
3676.39 2481 zinc finger protein 215 (bwscr2 associated zinc-finger protein 2) (baz 2). [swissprot;acc:q9ul58] 1.03015
3676.43 2477 zinc finger protein 24 (zinc finger protein 191) (zinc finger protein kox17) (retinoic acid suppression protein a) (rsg-a). [swissprot;acc:p17028] 3568.84
3676.56 2480 zinc finger protein 305. [swissprot;acc:o43309] 3568.95
3676.57 2478 zinc finger protein 232. [swissprot;acc:q9uny5] 3568.96
3676.6 2479 zinc finger protein 99. [refseq;acc:nm_032164] 3568.99
3676.61 2482 zinc finger protein 213 (putative transcription factor cr53). [swissprot;acc:o14771]
3676.7 2476 zinc finger protein 274 (zinc finger protein sp2114) (zinc finger protein hfb101) (zinc finger protein zfp2) (zf2). [swissprot;acc:q96gc6] 3569.07 1.03016
3682.14 2475 zinc finger protein 444; endothelial zinc finger protein 2. [refseq;acc:nm_018337] 3573.66 1.03036
3682.72 2360 60s ribosomal protein l4 (l1). [swissprot;acc:p36578] 3843.06 1.04354
3688.96 2634 ribosomal protein p0-like protein; 60s acidic ribosomal protein po; ribosomal protein, large, p0-like. [refseq;acc:nm_016183] 3640.58 1.01329
3705.05 2500 rna polymerase i associated factor 53. [refseq;acc:nm_022490] 3804.53 1.02685
3710.01 2523 dna-directed rna polymerase i 40 kda polypeptide (ec 2.7.7.6) (rpa40) (rpa39). [swissprot;acc:o15160] 3803.04 1.02508
3718.86 2539 ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial precursor (ec 1.10.2.2) (rieske iron-sulfur protein) (risp). [swissprot;acc:p47985] 3805.17 1.02321
3734.8 2486 maleylacetoacetate isomerase (ec 5.2.1.2) (maai) (glutathione s- transferase zeta 1) (ec 2.5.1.18) (gstz1-1). [swissprot;acc:o43708] 3626.38 1.0299
3754.96 2445 skeletal muscle lim-protein 3 (slim 3) (lim-domain protein dral) (four and a half lim domains protein 2) (fhl-2). [swissprot;acc:q14192] 3633.14 1.03353
3755.33 2220 cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747] 3936.2 1.04816
3755.5 2221 thrombospondin 3 precursor. [swissprot;acc:p49746] 3936.33 1.04815
3756.67 2443 skeletal muscle lim-protein 2 (slim 2) (four and a half lim domains protein 3) (fhl-3). [swissprot;acc:q13643] 3634.59 1.03359
3759.28 2533 dna-directed rna polymerase i 135 kda polypeptide (ec 2.7.7.6) (rna polymerase i subunit 2) (rpa135). [swissprot;acc:q9h9y6] 3847.84 1.02356
3762.56 317 adiponectin receptor 2. [refseq;acc:nm_024551] 3153.1 1.19329
3775.86 2553 ras-related protein rab-37. [swissprot;acc:q96ax2] 3852.99 1.02043
2554 ras-related protein rab-26. [swissprot;acc:q9ulw5]
2555 dna-directed rna polymerase ii 33 kda polypeptide (ec 2.7.7.6) (rpb3) (rna polymerase ii subunit 3) (rpb33) (rpb31). [swissprot;acc:p19387]
3788.42 2530 28s ribosomal protein s9, mitochondrial precursor (mrp-s9). [swissprot;acc:p82933] 3880.5 1.02431

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/