MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Filtered	green	Gene	Interaction Map	red	network_comparison	Value Type	Network Comparison Type	Rank	description

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

Filtered  : 0
green  : 0
Interaction Map  : High confidence
Network Comparison Type  : Subtracted

red	network_comparison	Value Type	Rank	description
0	0	Measured	494	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]
			495	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
			496	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
			497	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
			498	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
			499	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
			500	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
			501	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
			502	brca1 associated protein. [refseq;acc:nm_006768]
		Ranked	501	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
			502	brca1 associated protein. [refseq;acc:nm_006768]
		Squared	494	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]
			495	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
			496	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
			497	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
			498	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
			499	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
			500	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
			501	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
			502	brca1 associated protein. [refseq;acc:nm_006768]
		Rooted	494	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]
			495	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
			496	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
			497	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
			498	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
			499	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
			500	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
			501	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
			502	brca1 associated protein. [refseq;acc:nm_006768]
0.0766864	0.0766864	Squared	471	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]
0.289941	0.289941		467	dok-like protein. [refseq;acc:nm_024872]
0.852071	0.852071		449	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]
1.59148	1.59148		440	ero1-like. [refseq;acc:nm_014584]
4.24264	4.24264	Rooted	117	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]
5.61325	5.61325	Squared	409	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
			410	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
5.91608	5.91608	Rooted	74	dok-like protein. [refseq;acc:nm_024872]
7.74597	7.74597		50	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]
9.05539	9.05539		38	ero1-like. [refseq;acc:nm_014584]
12.4097	12.4097		17	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
			18	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
18	18	Measured	429	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]
19.0788	19.0788	Rooted	5	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]
31.36	31.36	Squared	357
35	35	Measured	386	dok-like protein. [refseq;acc:nm_024872]
60	60		338	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]
82	82		316	ero1-like. [refseq;acc:nm_014584]
154	154		206	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
			207	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
364	364		88	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.