Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Network Comparison Type Value Type Gene description Rank green network_comparison Filtered red Interaction Map
Results: HTML CSV LaTeX Showing element 1650 to 1699 of 3228 in total
Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1
Interaction Map  : High confidence
description
Rank
green
network_comparison
red
microfibril-associated glycoprotein 4 precursor. [swissprot;acc:p55083] 38 253 1.27273 322
microfibrillar-associated protein 1. [swissprot;acc:p55081] 2949 0.00001 1 0.00001
microsomal signal peptidase 18 kda subunit (ec 3.4.-.-) (spase 18 kda subunit) (spc18) (endopeptidase sp18). [swissprot;acc:p21378] 927 210.139 1.03713 217.942
microsomal signal peptidase 25 kda subunit (ec 3.4.-.-) (spase 25 kda subunit) (spc25). [swissprot;acc:q15005] 754 235.583 1.04968 224.434
microtubule-actin crosslinking factor 1, isoform 4. [swissprot;acc:q96pk2] 448 246.338 1.07822 228.468
microtubule-associated protein 4 (map 4). [swissprot;acc:p27816] 602 218.792 1.06069 206.274
microtubule-associated protein rp/eb family member 1 (apc-binding protein eb1). [swissprot;acc:q15691] 2719 216.632 1.00052 216.52
microtubule-associated protein rp/eb family member 3 (protein eb3). [swissprot;acc:q9upy8] 2720 216.633
microtubule-associated protein, rp/eb family, member 2; t-cell activation protein, eb1 family; apc-binding protein eb1. [refseq;acc:nm_014268] 2717 216.634 216.521
microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492] 16 75.3954 1.32913 56.7252
microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8] 15 75.3948 1.32914 56.7244
microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650] 2880 0.00001 1 0.00001
midasin (midas-containing protein). [swissprot;acc:q9nu22] 919 228.698 1.03725 237.218
mitochondrial 28s ribosomal protein s2 (mrp-s2) (cgi-91). [swissprot;acc:q9y399] 820 231.501 1.04413 221.716
mitochondrial 28s ribosomal protein s22 (s22mt) (mrp-s22) (gk002). [swissprot;acc:p82650] 2607 215.799 1.0014 215.497
mitochondrial 28s ribosomal protein s30 (s30mt) (mrp-s30) (programmed cell death protein 9) (bm047). [swissprot;acc:q9np92] 3063 0.00001 1 0.00001
mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3] 996 212.547 1.03345 219.656
mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932] 2825 0.00001 1 0.00001
mitochondrial 60s ribosomal protein l27 (l27mt) (hspc250). [swissprot;acc:q9p0m9] 955 239.205 1.03479 231.163
mitochondrial 60s ribosomal protein l3 (l3mt). [swissprot;acc:p09001] 318 266.18 1.09987 242.011
mitochondrial deoxynucleotide carrier (mitochondrial uncoupling protein 1). [swissprot;acc:q9hc21] 3014 0.00001 1 0.00001
mitochondrial ferritin; ferritin heavy chain-like; ferritin h subunit. [refseq;acc:nm_177478] 698 209.118 1.05413 220.437
mitochondrial gtp binding protein isoform v. [refseq;acc:nm_032620] 1095 207.463 1.02935 213.552
mitochondrial import inner membrane translocase subunit tim10. [swissprot;acc:q9y5j8] 730 219.708 1.05187 208.874
mitochondrial import inner membrane translocase subunit tim22. [swissprot;acc:q9y584] 455 226.578 1.07779 210.225
mitochondrial import receptor subunit tom20 homolog (mitochondrial 20 kda outer membrane protein) (outer mitochondrial membrane receptor tom20). [swissprot;acc:q15388] 840 190.66 1.04259 198.781
mitochondrial precursor proteins import receptor (translocase of outer membrane tom70). [swissprot;acc:o94826] 2610 215.799 1.0014 215.497
mitochondrial processing peptidase alpha subunit, mitochondrial precursor (ec 3.4.24.64) (alpha-mpp) (p-55) (ha1523). [swissprot;acc:q10713] 1300 212.576 1.02379 217.634
mitochondrial processing peptidase beta subunit, mitochondrial precursor (ec 3.4.24.64) (beta-mpp) (p-52). [swissprot;acc:o75439] 1299 212.575 1.0238 217.635
mitochondrial ribosomal protein l17; lyst-interacting protein lip2. [refseq;acc:nm_022061] 361 266.248 1.09644 242.83
mitochondrial ribosomal protein l18. [refseq;acc:nm_014161] 2246 224.943 1.0061 223.58
mitochondrial ribosomal protein l2. [refseq;acc:nm_015950] 305 266.986 1.1017 242.339
mitochondrial ribosomal protein l22. [refseq;acc:nm_014180] 487 243.03 1.07387 226.313
mitochondrial ribosomal protein l24. [refseq;acc:nm_024540] 1985 217.193 1.00952 219.26
mitochondrial ribosomal protein l30 isoform a. [refseq;acc:nm_145212] 2477 216.801 1.00289 216.177
mitochondrial ribosomal protein l4 isoform a. [refseq;acc:nm_015956] 296 266.12 1.10294 241.282
mitochondrial ribosomal protein s7; 30s ribosomal protein s7 homolog. [refseq;acc:nm_015971] 3016 0.00001 1 0.00001
mitochondrial ribosome recycling factor. [refseq;acc:nm_138777] 663 216.576 1.0577 229.072
mitochondrial solute carrier protein. [refseq;acc:nm_016612] 2915 0.00001 1 0.00001
mitochondrial solute carrier protein. [refseq;acc:nm_145305] 27 44 1.31818 58
mitochondrial translational release factor 1-like. [refseq;acc:nm_019041] 932 218.013 1.03636 225.939
mitogen-activated protein kinase 1 (ec 2.7.1.37) (extracellular signal-regulated kinase 2) (erk-2) (mitogen-activated protein kinase 2) (map kinase 2) (mapk 2) (p42-mapk) (ert1). [swissprot;acc:p28482] 2168 214.486 1.00673 215.929
mitogen-activated protein kinase 12 (ec 2.7.1.37) (extracellular signal-regulated kinase 6) (erk-6) (erk5) (stress-activated protein kinase-3) (mitogen-activated protein kinase p38 gamma) (map kinase p38 gamma). [swissprot;acc:p53778] 1263 167.177 1.02425 171.231
mitogen-activated protein kinase 14 (ec 2.7.1.37) (mitogen-activated protein kinase p38alpha) (map kinase p38alpha) (cytokine suppressive anti-inflammatory drug binding protein) (csaid binding protein) (csbp) (max-interacting protein 2) (map kinase mxi2) (sapk2a). [swissprot;acc:q16539] 1274
mitogen-activated protein kinase 3 (ec 2.7.1.37) (extracellular signal-regulated kinase 1) (erk-1) (insulin-stimulated map2 kinase) (map kinase 1) (mapk 1) (p44-erk1) (ert2) (p44-mapk) (microtubule- associated protein-2 kinase). [swissprot;acc:p27361] 2159 214.474 1.00675 215.921
mitogen-activated protein kinase kinase 1 interacting protein 1 (mek binding partner 1) (mp1) (pro2783). [swissprot;acc:q9uha4] 3084 0.00001 1 0.00001
mitogen-activated protein kinase kinase kinase 5 (ec 2.7.1.-) (mapk/erk kinase kinase 5) (mek kinase 5) (mekk 5) (apoptosis signal- regulating kinase 1) (ask-1). [swissprot;acc:q99683] 2174 214.481 1.00673 215.925
mitogen-activated protein kinase kinase kinase 6 (ec 2.7.1.-). [swissprot;acc:o95382] 2163
mitogen-activated protein kinase kinase kinase 7 (ec 2.7.1.-) (transforming growth factor-beta-activated kinase 1) (tgf-beta- activated kinase 1). [swissprot;acc:o43318] 1489 209.264 1.01905 213.251
mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (tak1-binding protein 1). [swissprot;acc:q15750] 2273 211.858 1.00546 213.015

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/