MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	network_comparison	Gene	Rank	green	description	Network Comparison Type	Value Type	red	Interaction Map

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Filtered  : 0
network_comparison  : 1
Network Comparison Type  : Divided

Rank	green	description	Value Type	red	Interaction Map
493	17901.1	3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	Squared	17901.1	High confidence
494	0.00001	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	Measured	0.00001
			Squared
			Rooted
495		histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]	Measured
			Squared
			Rooted
496		mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	Measured
			Squared
			Rooted
497		histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]	Measured
			Squared
			Rooted
498		translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]	Measured
			Squared
			Rooted
499		homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	Measured
			Squared
			Rooted
500		rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]	Measured
			Squared
			Rooted
	394	huntingtin interacting protein e; huntingtin interactor protein e. [refseq;acc:nm_007076]	Ranked	394
501	0.00001	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	Measured	0.00001
			Squared
			Rooted
		homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	Ranked
502		brca1 associated protein. [refseq;acc:nm_006768]	Measured
			Ranked
			Squared
			Rooted
836	17901.1	3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	Squared	17901.1	Low confidence
837	0.00001	gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]	Measured	0.00001
			Ranked
			Squared
			Rooted
838		gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]	Measured
			Ranked
			Squared
			Rooted
839		cobw-like protein. [refseq;acc:nm_018491]	Measured
			Ranked
			Squared
			Rooted
840		translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]	Measured
			Squared
			Rooted
	394	huntingtin interacting protein e; huntingtin interactor protein e. [refseq;acc:nm_007076]	Ranked	394
841	0.00001	gamma-glutamyltransferase. [sptrembl;acc:q14390]	Measured	0.00001
			Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.