Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered green description Value Type Interaction Map network_comparison Gene Rank red Network Comparison Type
Results: HTML CSV LaTeX Showing element 1 to 50 of 38536 in total
Filtered  : 0
green  : 0.00001
Network Comparison Type  : Divided
description
Value Type
Interaction Map
network_comparison
Rank
red
brca1 associated protein. [refseq;acc:nm_006768] Measured High confidence 1 502 0.00001
Ranked
Squared
Rooted
carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 6; macular dystrophy, corneal, 1; carbohydate sulfotransferase 6; corneal n-acetylglucosamine 6-sulfotransferase. [refseq;acc:nm_021615] Measured Low confidence 3700000 22 37
Squared 32402.4 5 0.324024
Rooted 608276 6 6.08276
carbohydrate (n-acetylglucosamine-6-o) sulfotransferase 2; carbohydrate (chondroitin 6/keratan) sulfotransferase 2. [refseq;acc:nm_004267] Measured 3700000 23 37
Squared 32402.4 6 0.324024
Rooted 608276 7 6.08276
cobw-like protein. [refseq;acc:nm_018491] Measured 1 839 0.00001
Ranked
Squared
Rooted
dok-like protein. [refseq;acc:nm_024872] Measured High confidence 3500000 31 35
Squared 28994.1 13 0.289941
Rooted 591608 5.91608
ero1-like. [refseq;acc:nm_014584] Measured 8200000 20 82
Squared 159148 8 1.59148
Rooted 905539 9.05539
gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920] Measured Low confidence 1 838 0.00001
Ranked
Squared
Rooted
gamma-glutamyltransferase. [sptrembl;acc:q14390] Measured 841
Ranked
Squared
Rooted
gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440] Measured 842
Ranked
Squared
Rooted
gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268] Measured 837
Ranked
Squared
Rooted
gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269] Measured 843
Ranked
Squared
Rooted
h2a histone family, member j isoform 1. [refseq;acc:nm_018267] Measured High confidence 501
Squared
Rooted
histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001] Measured 495
Squared
Rooted
histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261] Measured 494
Squared
Rooted
histone h2a; h2a histone family, member r. [refseq;acc:nm_170745] Measured 497

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/