MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

green	Interaction Map	Gene	Rank	network_comparison	Value Type	description	Filtered	Network Comparison Type	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

green  : 0.00001
Interaction Map  : High confidence
Filtered  : 0
Network Comparison Type  : Divided

Rank	network_comparison	Value Type	description	red
1	1907880	Rooted	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	19.0788
	36400000	Measured		364
2	561325	Squared	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]	5.61325
	1240970	Rooted		12.4097
3	561325	Squared	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]	5.61325
	1240970	Rooted		12.4097
8	159148	Squared	ero1-like. [refseq;acc:nm_014584]	1.59148
	905539	Rooted		9.05539
9	85207.1	Squared	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]	0.852071
	774597	Rooted		7.74597
13	28994.1	Squared	dok-like protein. [refseq;acc:nm_024872]	0.289941
	591608	Rooted		5.91608
15	424264		rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]	4.24264
17	7668.64	Squared		0.0766864
20	8200000	Measured	ero1-like. [refseq;acc:nm_014584]	82
22	6000000		similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]	60
31	3500000		dok-like protein. [refseq;acc:nm_024872]	35
65	1800000		rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]	18
68	3136000	Squared	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	31.36
95	15400000	Measured	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]	154
96			transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
494	1		histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	0.00001
		Squared
		Rooted
495		Measured	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
		Squared
		Rooted
496		Measured	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
		Squared
		Rooted
497		Measured	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
		Squared
		Rooted
498		Measured	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
		Squared
		Rooted
499		Measured	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
		Squared
		Rooted
500		Measured	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
		Squared
		Rooted
501		Measured	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
		Ranked	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
		Squared	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
		Rooted
502		Measured	brca1 associated protein. [refseq;acc:nm_006768]
		Ranked
		Squared
		Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.