MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Filtered	Value Type	Network Comparison Type	green	Interaction Map	red	network_comparison

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

description	Rank	Filtered	Value Type	Network Comparison Type	green	Interaction Map	red	network_comparison
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210]	1682	1	Ranked	Subtracted	199.408	High confidence	202.358	2.95
	1721		Squared	Divided	53788.1		59318.4	1.10282
	1772		Rooted	Subtracted	76.9113		74.9362	1.9751
	2059			Divided				1.02636
	2149		Ranked	Subtracted	197.22	Low confidence	200.982	3.762
	2163			Divided				1.01908
	2260		Rooted	Subtracted	74.792		72.3171	2.4749
	2297			Divided				1.03422
	2602		Measured	Subtracted	9234.09	High confidence	9150.44	83.65
	2651			Divided				1.00914
	2944			Subtracted	8314.51	Low confidence	8088.94	225.57
	3044			Divided				1.02789
26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524]	1280		Squared	Subtracted	30113.9	High confidence	27176.8	2937.1
	1577		Measured	Divided	6349.04		5923.66	1.07181
	1599			Subtracted				425.38
	1630		Squared	Divided	30113.9		27176.8	1.10807
	1944		Rooted		64.5421		62.7515	1.02853
	1968			Subtracted				1.7906
	2478		Ranked	Divided	216.801		216.177	1.00289
	2486			Subtracted				0.624
	2526		Measured		8326.51	Low confidence	8088.12	238.39
	2711			Divided				1.02947
	3092		Rooted	Subtracted	74.8438		72.5509	2.2929
	3167			Divided				1.0316
	3429		Squared	Subtracted	44345.7		45773.6	1427.9
	3515		Ranked	Divided	197.374		200.312	1.01489
	3521			Subtracted				2.938
	3537		Squared	Divided	44345.7		45773.6	1.0322
26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [swissprot;acc:q99460]	830		Ranked	Subtracted	199.229		204.36	5.131
	857			Divided				1.02575
	1146		Squared		42544.1		44506	1.04611
	1162		Rooted		73.5808		70.8788	1.03812
	1182		Squared	Subtracted	29969	High confidence	26860.7	3108.3
	1280		Rooted		73.5808	Low confidence	70.8788	2.702
	1379		Squared		42544.1		44506	1961.9
	1476			Divided	29969	High confidence	26860.7	1.11572
	1862		Measured	Subtracted	6195.48		5826	369.48
	1883			Divided				1.06342
	2129		Rooted		63.5033		62.0038	1.02418
	2140			Subtracted				1.4995
	2355		Ranked		219.434		218.555	0.879
	2368			Divided				1.00402
	2447		Measured		8063.51	Low confidence	7825.14	1.03046
	2527			Subtracted				238.37
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	104	0	Squared		7355.46	High confidence	8620.27	1264.81
	316			Divided				1.17196
	335		Rooted	Subtracted	32.0298		30.7424	1.2874
	370			Divided				1.04188
	378		Ranked	Subtracted	10806		11228.4	422.4
	379			Divided				1.03909

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.