MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	description	Filtered	Network Comparison Type	Interaction Map	Rank	Value Type	network_comparison	green	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

description	Filtered	Interaction Map	Rank	Value Type	network_comparison	green	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	0	High confidence	37	Measured	2.79409	934.348	334.401
				Squared	10.2338	1034.13	101.05
			53	Rooted	1.5213	18.0183	11.844
			242	Ranked	1.09822	13895.8	15260.6
		Low confidence	131	Measured	1.31954	851.77	645.504
			146	Squared	1.63527	1268.51	775.72
			537	Rooted	1.04801	17.0804	16.298
			629	Ranked	1.02915	13590.3	13205.3
	1	High confidence	18		1.32082	245.247	185.678
			60	Measured	1.6231	2765.82	4489.19
			64	Rooted	1.35128	47.2654	63.8686
			245	Squared	1.31131	6768.05	8875.01
		Low confidence	1119		1.04654	41688.5	43628.5
			4130	Ranked	1.01062	201.5	199.383
			4914	Measured	1.00597	7900.54	7853.62
				Rooted	1.00944	72.6287	71.9496
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]		High confidence	295	Squared	1.27733	39351.7	30807.7
			509	Measured	1.14278	8630.06	7551.8
			805	Rooted	1.0645	79.1513	74.3557
			1038	Ranked	1.03148	181.041	186.741
		Low confidence	885	Measured	1.03993	8585.64	8255.95
			1092	Rooted	1.0386	76.3375	73.5001
			1328	Ranked	1.02218	194.038	198.342
			4562	Squared	1.01928	45736	46617.7
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]		High confidence	294		1.2776	39383.9	30826.5
			508	Measured	1.14293	8636.87	7556.75
			804	Rooted	1.0646	79.1931	74.3877
			1032	Ranked	1.03162	180.943	186.664
		Low confidence	880	Measured	1.04001	8587.03	8256.68
			1084	Rooted	1.03863	76.3467	73.5068
			1322	Ranked	1.0222	194.014	198.322
			4569	Squared	1.01914	45740.5	46616.1
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]		High confidence	311		1.27154	38866.5	30566.4
			514	Measured	1.1411	8532.02	7477
			822	Rooted	1.06393	78.5795	73.8577
			1048	Ranked	1.031	182.308	187.96
		Low confidence	237	Measured	1.06457	9081.29	8530.51
			378	Rooted	1.04871	79.5804	75.8843
			588	Ranked	1.03039	185.859	191.507
			4138	Squared	1.02676	47372.8	46138.2
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]		High confidence	308		1.27205	38919.9	30596.2
			513	Measured	1.14143	8543.66	7485.08
			811	Rooted	1.06415	78.6514	73.9102
			1043	Ranked	1.03128	182.137	187.834
		Low confidence	252	Measured	1.06194	9018.94	8492.92
			427	Rooted	1.04731	79.1997	75.6219
			637	Ranked	1.029	186.751	192.166
			4418	Squared	1.02256	47088.3	46049.4
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]			2035	Measured	1.03199	8323.04	8065.05
			2766	Rooted	1.03282	74.9741	72.5914

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.