MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	Filtered	Rank	description	Network Comparison Type	Value Type	Interaction Map	green	red	network_comparison

Results: HTML CSV LaTeX

Showing element 451 to 500 of 9634 in total

Filtered  : 0
Network Comparison Type  : Divided
Value Type  : Measured

Rank	description	Interaction Map	green	red	network_comparison
226	cleavage stimulation factor, 64 kda subunit (cstf 64 kda subunit) (cf-1 64 kda subunit). [swissprot;acc:p33240]	High confidence	758.411	658.544	1.15165
	zinc finger protein 33a (zinc finger protein kox31) (ha0946). [swissprot;acc:q06730]	Low confidence	1968.69	2351.62	1.19451
227	similar to zinc finger protein 91 (hpf7, htf10) (fragment). [sptrembl;acc:q86w65]		1968.91	2351.86	1.1945
	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]	High confidence	369.011	424.258	1.14972
228	sh3-containing grb2-like protein 1 (sh3 domain protein 2b) (extra eleven-nineteen leukemia fusion gene) (een) (een fusion partner of mll). [swissprot;acc:q99961]		4696.36	4089.65	1.14835
	zinc finger protein 234 (zinc finger protein hzf4) (fragment). [swissprot;acc:q14588]	Low confidence	1968.83	2351.77	1.1945
229	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]	High confidence	368.317	320.752	1.14829
	zinc finger protein 41. [swissprot;acc:p51814]	Low confidence	1968.87	2351.81	1.1945
230	trans-prenyltransferase; polyprenyl pyrophosphate synthetase. [refseq;acc:nm_014317]	High confidence	1718.6	1498.17	1.14713
	zinc finger protein 300. [swissprot;acc:q96re9]	Low confidence	1968.91	2351.86	1.1945
231	alcohol dehydrogenase class iii chi chain (ec 1.1.1.1) (glutathione- dependent formaldehyde dehydrogenase) (ec 1.2.1.1) (fdh). [swissprot;acc:p11766]	High confidence	1759.22	2017.91	1.14705
	zinc finger protein zfp31 (fragment). [sptrembl;acc:q92971]	Low confidence	1968.91	2351.86	1.1945
232	60s ribosomal protein l17 (l23). [swissprot;acc:p18621]	High confidence	1906.28	1663.73	1.14579
	zinc finger protein 286. [swissprot;acc:q9hbt8]	Low confidence	1969.01	2351.96	1.19449
233	maguk p55 subfamily member 2 (mpp2 protein) (discs, large homolog 2). [swissprot;acc:q14168]	High confidence	399.534	348.823	1.14538
	zinc finger protein 7 (zinc finger protein kox4) (zinc finger protein hf.16). [swissprot;acc:p17097]	Low confidence	1969.01	2351.96	1.19449
234	wiskott-aldrich syndrome protein family member 3 (wasp-family protein member 3) (verprolin homology domain-containing protein 3). [swissprot;acc:q9upy6]	High confidence	4550.64	5202.89	1.14333
	zinc finger protein 304. [swissprot;acc:q9hcx3]	Low confidence	1969.05	2352.01	1.19449
235	integrin beta-3 precursor (platelet membrane glycoprotein iiia) (gpiiia) (cd61 antigen). [swissprot;acc:p05106]	High confidence	1843.92	1612.86	1.14326
	zinc finger protein 83 (zinc finger protein hpf1). [swissprot;acc:p51522]	Low confidence	1968.97	2351.92	1.19449
236	f23269_2. [sptrembl;acc:o75290]		1969.11	2352.07	1.19448
	peroxisomal acyl-coenzyme a thioester hydrolase 2a (ec 3.1.2.2) (peroxisomal long-chain acyl-coa thioesterase 2) (zap128). [swissprot;acc:p49753]	High confidence	3103.01	2715.75	1.1426
237	dj54b20.4 (novel krab box containing c2h2 type zinc finger protein). [sptrembl;acc:q96qh7]	Low confidence	1969.25	2352.23	1.19448
	p28 ing5. [refseq;acc:nm_032329]	High confidence	2243.69	2551.23	1.13707
238	casein kinase i alpha s-like. [refseq;acc:nm_145203]		1933.94	2198.47	1.13678
	zinc finger protein 415. [refseq;acc:nm_018355]	Low confidence	1969.15	2352.12	1.19448
239	guanine nucleotide-binding protein g(q), alpha subunit. [swissprot;acc:p50148]	High confidence	434.366	382.142	1.13666
	zinc finger protein 35 (zinc finger protein hf.10). [swissprot;acc:p13682]	Low confidence	1969.29	2352.27	1.19448
240	putative eukaryotic translation initiation factor 1a (eif-1a) (eif- 4c). [swissprot;acc:o75642]	High confidence	1676.18	1475.83	1.13575
	zinc finger protein 10 (zinc finger protein kox1) (fragment). [swissprot;acc:p21506]	Low confidence	1969.19	2352.16	1.19448
241	keratin associated protein 9.2. [refseq;acc:nm_031961]	High confidence	1079.01	1225.47	1.13574
	zinc finger protein 225. [swissprot;acc:q9uk10]	Low confidence	1969.19	2352.16	1.19448
242	splicing factor 3b subunit 3 (spliceosome associated protein 130) (sap 130) (sf3b130) (pre-mrna splicing factor sf3b 130 kda subunit). [swissprot;acc:q15393]	High confidence	642.343	729.216	1.13524
	zinc finger protein 256 (bone marrow zinc finger 3) (bmzf-3). [swissprot;acc:q9y2p7]	Low confidence	1969.19	2352.16	1.19448
243	keratin associated protein 4.3 (fragment). [sptrembl;acc:q9byr4]	High confidence	1079.36	1225.09	1.13502
	zinc finger protein 214 (bwscr2 associated zinc-finger protein 1) (baz 1). [swissprot;acc:q9ul59]	Low confidence	1969.19	2352.16	1.19448
244	dj54b20.2 (novel krab box containing c2h2 type zinc finger protein) (fragment). [sptrembl;acc:q96qh9]		1969.25	2352.23
	keratin associated protein 2-4; keratin associated protein 2.4. [refseq;acc:nm_033184]	High confidence	1079.36	1225.09	1.13502
245	keratin associated protein 1.5. [refseq;acc:nm_031957]
	zinc finger protein 165 (ld65). [swissprot;acc:p49910]	Low confidence	1969.19	2352.16	1.19448
246	ba526d8.4 (novel krab box containing c2h2 type zinc finger protein) (fragment). [sptrembl;acc:q9h559]		1969.25	2352.23
	keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [swissprot;acc:p26371]	High confidence	1079.36	1225.09	1.13502
247	dj153g14.3 (novel c2h2 type zinc finger protein) (fragment). [sptrembl;acc:q9ujn7]	Low confidence	1969.11	2352.07	1.19448
	keratin associated protein 1-3; keratin associated protein 1.3. [refseq;acc:nm_030966]	High confidence	1079.36	1225.09	1.13502
248	keratin associated protein 4-10; keratin associated protein 4.10. [refseq;acc:nm_033060]		1079.37		1.135
	zinc finger protein 264. [swissprot;acc:o43296]	Low confidence	1969.15	2352.12	1.19448
249	keratin associated protein 4-14; keratin associated protein 4.14. [refseq;acc:nm_033059]	High confidence	1079.37	1225.08	1.135
	zinc finger protein 228. [swissprot;acc:q9uju3]	Low confidence	1969.25	2352.23	1.19448
250	keratin associated protein 4.9 (fragment). [sptrembl;acc:q9byq8]	High confidence	1079.37	1225.08	1.135
	zinc finger protein 224. [swissprot;acc:q9nzl3]	Low confidence	1969.49	2352.49	1.19447

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.