MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	description	Network Comparison Type	Gene	Hugo	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1358 to 1407 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Hugo	Value Type
3095	erythroid differentiation-related factor 1. [refseq;acc:nm_015608]	C10orf137	Ranked
			Squared
			Rooted
3096	nucleoplasmin 3. [swissprot;acc:o75607]	NPM3	Measured
			Ranked
			Squared
			Rooted
3097	sec23-interacting protein p125; phospholipase. [refseq;acc:nm_007190]	SEC23IP	Measured
			Ranked
			Squared
			Rooted
3098	enhancer of zeste homolog 2 (enx-1). [swissprot;acc:q15910]	EZH2	Measured
			Ranked
			Squared
			Rooted
3099	caveolin-1. [swissprot;acc:q03135]	CAV1	Measured
			Ranked
			Squared
			Rooted
3100	presenilin enhancer 2; hematopoietic stem/progenitor cells protein mds033. [refseq;acc:nm_172341]	no value	Measured
			Ranked
			Squared
			Rooted
3101	gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284]		Measured
			Ranked
			Squared
			Rooted
3102	protein cgi-140 (protein ptd008) (my006 protein). [swissprot;acc:q9y284]	C19orf56	Measured
			Ranked
			Squared
			Rooted
3103	dna ligase i (ec 6.5.1.1) (polydeoxyribonucleotide synthase [atp]). [swissprot;acc:p18858]	LIG1	Measured
			Ranked
			Squared
			Rooted
3104	glioma tumor suppressor candidate region gene 2 protein (p60). [swissprot;acc:q9nzm5]	SNORD23	Measured
			Ranked
			Squared
			Rooted
3105	transforming growth factor beta 1 precursor (tgf-beta 1). [swissprot;acc:p01137]	TGFB1	Measured
			Ranked
			Squared
			Rooted
3106	prostate tumor overexpressed gene 1; prostate tumor over expressed gene 1. [refseq;acc:nm_017432]	PTOV1	Measured
			Ranked
			Squared
			Rooted
3107	lyl-1 protein (lymphoblastic leukemia derived sequence 1). [swissprot;acc:p12980]	LYL1	Measured
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.