Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered Value Type Gene green network_comparison Rank description Interaction Map red Network Comparison Type
Results: HTML CSV LaTeX Showing element 501 to 550 of 29840 in total
Filtered  : 0
Value Type  : Measured
Interaction Map  : High confidence
green
network_comparison
Rank
description
red
Network Comparison Type
898 1.78508 67 filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333] 1603 Divided
705 35 Subtracted
898.833 1.06564 349 kinesin-like protein kif13b (kinesin-like protein gakin). [swissprot;acc:q9nqt8] 957.833 Divided
59 345 Subtracted
904.149 1.21678 191 ba395l14.12 (novel protein similar to small nuclear ribonucleoprotein polypeptide a' (snrpa1)). [sptrembl;acc:q9nu36] 743.066 Divided
161.083 197 Subtracted
925.298 1.71412 75 oligosaccharyl transferase stt3 subunit homolog (b5) (integral membrane protein 1) (tmc). [swissprot;acc:p46977] 1586.07 Divided
660.772 36 Subtracted
931.405 1.05332 377 atp-dependent clp protease atp-binding subunit clpx-like, mitochondrial precursor. [swissprot;acc:o76031] 884.254 Divided
47.151 371 Subtracted
934.348 2.79409 37 1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 334.401 Divided
599.947 45 Subtracted
943.423 1.19157 206 pms1 protein homolog 2 (dna mismatch repair protein pms2). [swissprot;acc:p54278] 1124.15 Divided
180.727 177 Subtracted
961.098 1.00278 484 scribble. [refseq;acc:nm_015356] 958.429 Divided
2.669 488 Subtracted
975.647 1.12024 277 disks large-associated protein 2 (dap-2) (sap90/psd-95-associated protein 2) (sapap2) (psd-95/sap90 binding protein 2) (fragment). [swissprot;acc:q9p1a6] 870.93 Divided
104.717 267 Subtracted
977 1.47595 101 putative phosphoglycerate mutase 3 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13). [swissprot;acc:q8n0y7] 1442 Divided
102 phosphoglycerate mutase 1 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13) (phosphoglycerate mutase isozyme b) (pgam-b) (bpg-dependent pgam 1). [swissprot;acc:p18669]
465 62 putative phosphoglycerate mutase 3 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13). [swissprot;acc:q8n0y7] Subtracted
63 phosphoglycerate mutase 1 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13) (phosphoglycerate mutase isozyme b) (pgam-b) (bpg-dependent pgam 1). [swissprot;acc:p18669]
988.882 1.06044 369 dna directed rna polymerase ii polypeptide j-related gene isoform 1; rpb11b1alpha protein; rpb11b1beta; dna-directed rna polymerase ii subunit 11. [refseq;acc:nm_145325] 1048.65 Divided
59.768 340 Subtracted
989.438 1.06041 370 dna directed rna polymerase ii polypeptide j-related gene isoform 3; rpb11b1alpha protein; rpb11b1beta; dna-directed rna polymerase ii subunit 11. [refseq;acc:nm_032959] 1049.21 Divided
59.772 339 Subtracted
992.083 1.73441 72 60s ribosomal protein l21. [swissprot;acc:p46778] 572 Divided
420.083 75 Subtracted
1023.76 1.22025 189 pyrroline-5-carboxylate reductase (ec 1.5.1.2) (p5cr) (p5c reductase). [swissprot;acc:p32322] 1249.24 Divided
225.48 148 Subtracted
1026.18 1.19915 199 glutamine synthetase (ec 6.3.1.2) (glutamate--ammonia ligase). [swissprot;acc:p15104] 1230.54 Divided
204.36 161 Subtracted
1068 1.75947 70 importin alpha-2 subunit (karyopherin alpha-2 subunit) (srp1-alpha) (rag cohort protein 1). [swissprot;acc:p52292] 607 Divided
461 64 Subtracted
1070.03 1.07338 339 glycine dehydrogenase [decarboxylating], mitochondrial precursor (ec 1.4.4.2) (glycine decarboxylase) (glycine cleavage system p- protein). [swissprot;acc:p23378] 996.883 Divided
73.147 320 Subtracted
1079.01 1.13574 241 keratin associated protein 9.2. [refseq;acc:nm_031961] 1225.47 Divided
146.46 218 Subtracted
1079.36 1.13502 243 keratin associated protein 4.3 (fragment). [sptrembl;acc:q9byr4] 1225.09 Divided
244 keratin associated protein 2-4; keratin associated protein 2.4. [refseq;acc:nm_033184]
245 keratin associated protein 1.5. [refseq;acc:nm_031957]
246 keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [swissprot;acc:p26371]
247 keratin associated protein 1-3; keratin associated protein 1.3. [refseq;acc:nm_030966]
145.73 221 keratin associated protein 4.3 (fragment). [sptrembl;acc:q9byr4] Subtracted
222 keratin associated protein 2-4; keratin associated protein 2.4. [refseq;acc:nm_033184]
223 keratin associated protein 1.5. [refseq;acc:nm_031957]
224 keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [swissprot;acc:p26371]
225 keratin associated protein 1-3; keratin associated protein 1.3. [refseq;acc:nm_030966]
1079.37 1.135 248 keratin associated protein 4-10; keratin associated protein 4.10. [refseq;acc:nm_033060] Divided
249 keratin associated protein 4-14; keratin associated protein 4.14. [refseq;acc:nm_033059] 1225.08

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/