Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene Network Comparison Type description red Value Type green Interaction Map Filtered network_comparison
Results: HTML CSV LaTeX Showing element 601 to 650 of 1892 in total
Network Comparison Type  : Subtracted
red  : 0
green  : 0
Interaction Map  : High confidence
Filtered  : 1
network_comparison  : 0
Rank
description
Value Type
2906 thousand and one amino acid protein kinase. [refseq;acc:nm_004783] Measured
Ranked
Squared
Rooted
2907 fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075] Measured
Ranked
Squared
Rooted
2908 serine/threonine-protein kinase chk1 (ec 2.7.1.-). [swissprot;acc:o14757] Measured
Ranked
Squared
Rooted
2909 nk6 transcription factor related, locus 2; nk homeobox family 6, b; glial and testis-specific homeobox protein; homeobox 6b. [refseq;acc:nm_177400] Measured
Ranked
Squared
Rooted
2910 protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992] Measured
Ranked
Squared
Rooted
2911 bup protein. [refseq;acc:nm_012071] Measured
Ranked
Squared
Rooted
2912 inositol polyphosphate-5-phosphatase; phosphatidylinositol polyphosphate 5-phosphatase type iv; phosphatidylinositol (4,5) bisphosphate 5-phosphatase. [refseq;acc:nm_019892] Measured
Ranked
Squared
Rooted
2913 au rna-binding protein/enoyl-coenzyme a hydratase precursor; au rna-binding protein/enoyl-coenzyme a hydratase; 3-methylglutaconyl-coa hydratase; mga type i. [refseq;acc:nm_001698] Measured
Ranked
Squared
Rooted
2914 lactamase, beta 2. [refseq;acc:nm_016027] Measured
Ranked
Squared
Rooted
2915 mitochondrial solute carrier protein. [refseq;acc:nm_016612] Measured
Ranked
Squared
Rooted
2916 ribose-phosphate pyrophosphokinase i (ec 2.7.6.1) (phosphoribosyl pyrophosphate synthetase i) (ppribp) (prs-i). [swissprot;acc:p09329] Measured
Ranked
Squared
Rooted
2917 t-complex protein 1, zeta subunit (tcp-1-zeta) (cct-zeta) (cct-zeta-1) (tcp20) (htr3). [swissprot;acc:p40227] Measured
Ranked
Squared
Rooted
2918 nipsnap2 protein (glioblastoma amplified sequence). [swissprot;acc:o75323] Measured
Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/