MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	description	Filtered	Gene	green	Value Type	Interaction Map	Network Comparison Type	network_comparison	red

Results: HTML CSV LaTeX

Showing element 551 to 600 of 38536 in total

Network Comparison Type  : Divided

Rank	description	Filtered	green	Value Type	Interaction Map	network_comparison	red
35	guanine nucleotide-binding protein g(q), alpha subunit. [swissprot;acc:p50148]	1	907.564	Measured	High confidence	2.02378	1836.71
	melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]	0	5.80678	Rooted	Low confidence	1.69589	9.84765
	melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]		35.5	Measured		2.97183	105.5
	melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]		0.355148	Squared		9.62112	3.41692
	necdin. [swissprot;acc:q99608]	1	61881.5			1.33073	82347.8
	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	0	4871.6	Ranked	High confidence	1.5182	3208.8
	nuclear transcription factor y subunit gamma (nf-y protein chain c) (nuclear factor yc) (nf-yc) (ccaat-binding transcription factor subunit c) (cbf-c) (transactivator hsm-1/2). [swissprot;acc:q13952]	1	204.309			1.27519	260.532
	protein tyrosine phosphatase type iva, member 2 isoform 1; protein tyrosine phosphatase iva2; protein tyrosine phosphatase iva; phosphatase of regenerating liver 2. [refseq;acc:nm_003479]	0	16243		Low confidence	1.37553	11808.5
	regulator of g-protein signaling 12 (rgs12). [swissprot;acc:o14924]	1	63.2347	Rooted		1.15329	54.8296
	tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106]		258.59	Ranked		1.14959	297.273
36	4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]	0	2.18581	Rooted	High confidence	1.96964	4.30525
	ccaat-binding transcription factor subunit b (cbf-b) (nf-y protein chain a) (nf-ya) (caat-box dna binding protein subunit a). [swissprot;acc:p23511]	1	204.309	Ranked		1.27519	260.532
	cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336]	0	8.01325	Squared		10.5625	84.64
	chromatin accessibility complex protein 1 (chrac-1) (chrac-15) (huchrac15) (dna polymerase epsilon subunit p15). [swissprot;acc:q9nrg0]	1	64.217	Rooted	Low confidence	1.15273	55.7086
	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]	0	14964	Ranked	High confidence	1.4984	22422
	guanine nucleotide-binding protein g(z), alpha subunit (g(x) alpha chain) (gz-alpha). [swissprot;acc:p19086]	1	24.369	Rooted		1.65294	40.2805
			907.741	Measured		2.02344	1836.76
	heparan sulfate 6-o-sulfotransferase 2. [refseq;acc:nm_147174]	0	56			2.80357	157
	hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]		5.80678	Rooted	Low confidence	1.69589	9.84765
	melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]		35.5	Measured		2.97183	105.5
	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]		0.355148	Squared		9.62112	3.41692
	melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]	1	61881.5			1.33073	82347.8
	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]		192141		High confidence	1.80879	106226
	proto-oncogene protein c-fos (cellular oncogene fos) (g0/g1 switch regulatory protein 7). [swissprot;acc:p01100]		7593.77	Measured	Low confidence	1.17513	6462.09
	sam-domain protein samsn-1 (sam domain, sh3 domain and nuclear localisation signals protein 1). [swissprot;acc:q9nsi8]	0	9520.8	Ranked		1.37097	13052.7
	tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616]	1	258.33			1.14906	296.837
37	1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	0	934.348	Measured	High confidence	2.79409	334.401
			1034.13	Squared		10.2338	101.05
	chromatin accessibility complex protein 1 (chrac-1) (chrac-15) (huchrac15) (dna polymerase epsilon subunit p15). [swissprot;acc:q9nrg0]	1	217.843	Ranked	Low confidence	1.14874	250.244
	dj570f3.6 (novel protein similar to lysophospholipase ii (lypla2)). [sptrembl;acc:q9uge0]	0	2582		High confidence	1.49458	3859
	guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [swissprot;acc:p11488]	1	24.3691	Rooted		1.65293	40.2805
			907.763	Measured		2.02339	1836.76
	jun dimerization protein. [refseq;acc:nm_130469]		7593.77		Low confidence	1.17513	6462.09
	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]	0	0.355148	Squared		9.62112	3.41692
	melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]		5.80678	Rooted		1.69589	9.84765
	melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]		35.5	Measured		2.97183	105.5
	melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]	1	61881.5	Squared		1.33073	82347.8
	myotubularin related protein 8. [refseq;acc:nm_017677]	0	8993.6	Ranked		1.36786	12302
	pantothenate kinase 2, mitochondrial precursor (ec 2.7.1.33) (pantothenic acid kinase 2) (hpank2). [swissprot;acc:q9bz23]	1	192141	Squared	High confidence	1.80879	106226
	protein phosphatase 1, regulatory (inhibitor) subunit 14a; 17-kda pkc-potentiated inhibitory protein of pp1. [refseq;acc:nm_033256]		253	Ranked		1.27273	322
	small nuclear ribonucleoprotein associated proteins b and b' (snrnp-b) (sm protein b/b') (sm-b/sm-b') (smb/smb'). [swissprot;acc:p14678]	0	9.39626	Rooted		1.94348	4.83477
	testis-specific protein tex28. [swissprot;acc:o15482]	1	59.166		Low confidence	1.14428	51.7058
38	27 kda golgi snare protein (golgi snap receptor complex member 2) (membrin). [swissprot;acc:o14653]
	cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336]	0	10771	Ranked	High confidence	1.48976	7230
	glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926]		0.52284	Squared		9.25713	4.84
	glucosamine-6-phosphate isomerase. [refseq;acc:nm_138335]	1	282.937	Ranked	Low confidence	1.14456	247.202
	guanine nucleotide-binding protein g(t), alpha-2 subunit (transducin alpha-2 chain). [swissprot;acc:p19087]		24.3692	Rooted	High confidence	1.65292	40.2804
			907.774	Measured		2.02337	1836.76
	melanoma antigen, family b, 6. [refseq;acc:nm_173523]		61881.5	Squared	Low confidence	1.33073	82347.8
	melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]	0	0.355148			9.62112	3.41692

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.