Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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description Value Type green Gene Rank Network Comparison Type Interaction Map Filtered red network_comparison
Results: HTML CSV LaTeX Showing element 101 to 150 of 3228 in total
Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1
description
green
Rank
red
network_comparison
5-aminolevulinic acid synthase, erythroid-specific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-e). [swissprot;acc:p22557] 195.08 2491 194.527 1.00284
5-aminolevulinic acid synthase, nonspecific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-h). [swissprot;acc:p13196] 2496
5-formyltetrahydrofolate cyclo-ligase (ec 6.3.3.2) (5,10-methenyl- tetrahydrofolate synthetase) (methenyl-thf synthetase) (mthfs). [swissprot;acc:p49914] 210.642 2754 210.638 1.00002
5-methyltetrahydrofolate--homocysteine methyltransferase (ec 2.1.1.13) (methionine synthase, vitamin-b12 dependent) (ms). [swissprot;acc:q99707] 219.386 1921 221.607 1.01012
54 kda nuclear rna- and dna-binding protein (p54(nrb)) (p54nrb) (55 kda nuclear protein) (nmt55) (non-pou domain-containing octamer- binding protein) (dna-binding p52/p100 complex, 52 kda subunit). [swissprot;acc:q15233] 190.812 2532 190.405 1.00214
6-phosphofructokinase, liver type (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme b) (pfk-b). [swissprot;acc:p17858] 243.085 1822 240.32 1.01151
6-phosphofructokinase, muscle type (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme a) (pfk-a) (phosphofructokinase-m). [swissprot;acc:p08237] 243.069 1830 1.01144
6-phosphofructokinase, type c (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme c) (pfk-c) (6-phosphofructokinase, platelet type). [swissprot;acc:q01813] 242.881 1883 240.317 1.01067
6-phosphogluconate dehydrogenase, decarboxylating (ec 1.1.1.44). [swissprot;acc:p52209] 214.801 2274 213.642 1.00542
6-phosphogluconolactonase (ec 3.1.1.31) (6pgl). [swissprot;acc:o95336] 220.432 1584 216.891 1.01633
6-pyruvoyl tetrahydrobiopterin synthase (ec 4.2.3.12) (ptps) (ptp synthase). [swissprot;acc:q03393] 0.00001 2904 0.00001 1
60 kda heat shock protein, mitochondrial precursor (hsp60) (60 kda chaperonin) (cpn60) (heat shock protein 60) (hsp-60) (mitochondrial matrix protein p1) (p60 lymphocyte protein) (hucha60). [swissprot;acc:p10809] 222.64 2588 222.305 1.00151
60 kda tat interactive protein (tip60) (hiv-1 tat interactive protein) (cpla(2) interacting protein). [swissprot;acc:q92993] 213.912 826 223.186 1.04335
60s acidic ribosomal protein p0 (l10e). [swissprot;acc:p05388] 232.855 1092 226.203 1.02941
60s acidic ribosomal protein p1. [swissprot;acc:p05386] 238.048 898 229.171 1.03874
60s acidic ribosomal protein p2. [swissprot;acc:p05387] 244.435 720 231.92 1.05396
60s ribosomal protein l10 (qm protein) (tumor suppressor qm) (laminin receptor homolog). [swissprot;acc:p27635] 266.661 357 243.12 1.09683
60s ribosomal protein l10a (csa-19). [swissprot;acc:p53025] 266.796 356 243.24 1.09684
60s ribosomal protein l11, mitochondrial precursor (l11mt) (cgi-113). [swissprot;acc:q9y3b7] 265.255 373 242.37 1.09442
60s ribosomal protein l11. [swissprot;acc:p39026] 267.346 283 241.828 1.10552
60s ribosomal protein l12 like protein. [sptrembl;acc:o60886] 267.528 338 243.583 1.0983
60s ribosomal protein l12, mitochondrial precursor (l12mt) (5c5-2). [swissprot;acc:p52815] 265.104 369 242.159 1.09475
60s ribosomal protein l12. [swissprot;acc:p30050] 267.527 337 243.583 1.0983
60s ribosomal protein l13, mitochondrial (l13mt). [swissprot;acc:q9byd1] 263.62 390 241.828 1.09011
60s ribosomal protein l13a (23 kda highly basic protein). [swissprot;acc:p40429] 263.615 392 241.83 1.09008
60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914] 266.673 306 242.153 1.10126
60s ribosomal protein l15. [swissprot;acc:p39030] 230.978 604 217.862 1.0602
60s ribosomal protein l17 (l23). [swissprot;acc:p18621] 267.335 281 241.808 1.10557
60s ribosomal protein l18. [swissprot;acc:q07020] 254.667 485 237.109 1.07405
60s ribosomal protein l18a. [swissprot;acc:q02543] 224.958 860 234.025 1.04031
60s ribosomal protein l19. [swissprot;acc:p14118] 264.729 319 240.73 1.09969
60s ribosomal protein l21. [swissprot;acc:p46778] 217.263 1054 223.958 1.03082
60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268] 200.413 2205 199.129 1.00645
60s ribosomal protein l23 (l17). [swissprot;acc:p23131] 265.717 293 240.782 1.10356
60s ribosomal protein l23a. [swissprot;acc:p29316] 265.945 323 241.884 1.09947
60s ribosomal protein l24 (l30). [swissprot;acc:p38663] 198.86 1767 201.288 1.01221
60s ribosomal protein l26. [swissprot;acc:q02877] 267.008 302 242.326 1.10185
60s ribosomal protein l28. [swissprot;acc:p46779] 213.61 1882 215.896 1.0107
60s ribosomal protein l29 (cell surface heparin binding protein hip). [swissprot;acc:p47914] 204.549 2664 204.768 1.00107
60s ribosomal protein l3-like. [swissprot;acc:q92901] 266.663 312 242.195 1.10103
60s ribosomal protein l30. [swissprot;acc:p04645] 265.365 378 242.593 1.09387
60s ribosomal protein l31. [swissprot;acc:p12947] 224.958 862 234.025 1.04031
60s ribosomal protein l32. [swissprot;acc:p02433] 266.969 276 241.13 1.10716
60s ribosomal protein l34, mitochondrial precursor (l34mt). [swissprot;acc:q9bq48] 215.78 1333 220.681 1.02271
60s ribosomal protein l34. [swissprot;acc:p49207] 266.673 308 242.153 1.10126
60s ribosomal protein l35. [swissprot;acc:p42766] 266.999 303 242.333 1.10179
60s ribosomal protein l36, mitochondrial precursor (l36mt) (brca1- interacting protein 1). [swissprot;acc:q9p0j6] 266.07 365 242.744 1.09609
60s ribosomal protein l37 (g1.16). [swissprot;acc:p02403] 242.258 635 228.639 1.05957
60s ribosomal protein l37a. [swissprot;acc:p12751] 0.00001 2959 0.00001 1
60s ribosomal protein l39. [swissprot;acc:p02404] 224.958 859 234.025 1.04031

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/