MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Interaction Map	Network Comparison Type	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 601 to 650 of 3730 in total

Value Type  : Ranked
Interaction Map  : High confidence
Network Comparison Type  : Divided

Rank	description	Filtered	red	network_comparison	green
301	beta-1,4 mannosyltransferase. [refseq;acc:nm_019109]	1	150.982	1.10193	166.372
	sh2-b homolog; likely ortholog of mouse sh2 domain-containing putative adapter sh2-b; sh2-b gamma signaling protein; sh2-b alpha signaling protein. [refseq;acc:nm_015503]	0	12783	1.07158	13698
302	60s ribosomal protein l26. [swissprot;acc:q02877]	1	242.326	1.10185	267.008
	guanine nucleotide-binding protein beta subunit-like protein 12.3 (p205) (receptor of activated protein kinase c 1) (rack1) (receptor for activated c kinase). [swissprot;acc:p25388]	0	7386.71	1.07125	6895.44
303	60s ribosomal protein l35. [swissprot;acc:p42766]	1	242.333	1.10179	266.999
	intersectin 2 (sh3 domain-containing protein 1b) (sh3p18) (sh3p18-like wasp associated protein). [swissprot;acc:q9nzm3]	0	11431.4	1.07109	12244.1
304	40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]	1	242.339	1.1017	266.986
	sprouty homolog 4 (spry-4). [swissprot;acc:q9c004]	0	8021.78	1.07003	7496.8
305	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]		9431	1.06988	8815
	mitochondrial ribosomal protein l2. [refseq;acc:nm_015950]	1	242.339	1.1017	266.986
306	60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]		242.153	1.10126	266.673
	williams-beuren syndrome chromosome region 14 protein (ws basic-helix- loop-helix leucine zipper protein) (ws-bhlh) (mlx interactor). [swissprot;acc:q9np71]	0	5540	1.06877	5921
307	ba271b5.1 (similar to ribosomal protein s7). [sptrembl;acc:q9h1s9]		1091	1.06856	1021
	serine racemase (ec 5.1.1.-). [swissprot;acc:q9gzt4]	1	242.153	1.10126	266.673
308	60s ribosomal protein l34. [swissprot;acc:p49207]
	intersectin 1 (sh3 domain-containing protein 1a) (sh3p17). [swissprot;acc:q15811]	0	11414.1	1.06814	12191.8
309	lipopolysaccharide-binding protein precursor (lbp). [swissprot;acc:p18428]		13651	1.06747	14572
	protein transport protein sec61 alpha subunit isoform 2 (sec61 alpha- 2). [swissprot;acc:q9y2r3]	1	242.153	1.10126	266.673
310	glycine cleavage system h protein, mitochondrial precursor. [swissprot;acc:p23434]	0	9328.78	1.06718	8741.55
	protein transport protein sec61 alpha subunit isoform 1 (sec61 alpha- 1). [swissprot;acc:p38378]	1	242.153	1.10126	266.673
311	60s ribosomal protein l23 (l17). [swissprot;acc:p23131]	0	10253.5	1.06558	9622.45
	protein translation factor sui1 homolog gc20. [swissprot;acc:o60739]	1	242.627	1.10108	267.151
312	60s ribosomal protein l3-like. [swissprot;acc:q92901]		242.195	1.10103	266.663
	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	0	11959.8	1.06449	12731.1
313	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]		11935.6	1.06395	12698.9
	ribonucleotide reductase m2 b (tp53 inducible); p53-inducible ribonucleotide reductase small subunit 2 homolog. [refseq;acc:nm_015713]	1	232.473	1.10069	211.207
314	clathrin heavy chain 2 (clh-22). [swissprot;acc:p53675]	0	10301.4	1.06369	10957.5
	methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582]	1	244.126	1.10027	268.604
315	methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579]
	ribonucleoside-diphosphate reductase m1 chain (ec 1.17.4.1) (ribonucleotide reductase large chain). [swissprot;acc:p23921]	0	12121.6	1.06319	12887.6
316	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]		10768.5	1.06273	11444
	protein translation factor sui1 homolog (sui1iso1). [swissprot;acc:p41567]	1	242.694	1.10022	267.017
317	protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]	0	19939	1.06183	18778
	splicing factor 3b subunit 3 (spliceosome associated protein 130) (sap 130) (sf3b130) (pre-mrna splicing factor sf3b 130 kda subunit). [swissprot;acc:q15393]	1	224.445	1.09998	204.044
318	mitochondrial 60s ribosomal protein l3 (l3mt). [swissprot;acc:p09001]		242.011	1.09987	266.18
	ubiquitous tropomodulin (u-tmod) (tropomodulin 3). [swissprot;acc:q9nyl9]	0	8918.54	1.06131	9465.32
319	60s ribosomal protein l19. [swissprot;acc:p14118]	1	240.73	1.09969	264.729
	sorting nexin 9 (sh3 and px domain-containing protein 1) (sdp1 protein). [swissprot;acc:q9y5x1]	0	8918.54	1.06131	9465.32
320	adp-ribosylation factor 3. [swissprot;acc:p16587]		11627.8	1.0611	10958.2
	epithelial-cadherin precursor (e-cadherin) (uvomorulin) (cadherin-1) (cam 120/80). [swissprot;acc:p12830]	1	241.892	1.0995	265.96
321	adenine phosphoribosyltransferase (ec 2.4.2.7) (aprt). [swissprot;acc:p07741]	0	11634.4	1.05864	10989.9
	c367g8.3 (novel protein similar to rpl23a (60s ribosomal protein l23a)) (60s ribosomal protein l23a like). [sptrembl;acc:q9br02]	1	241.892	1.09949	265.959
322	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]		86.7483	1.09948	78.8995
	estradiol 17 beta-dehydrogenase 1 (ec 1.1.1.62) (17-beta-hsd 1) (placental 17-beta-hydroxysteroid dehydrogenase) (20 alpha- hydroxysteroid dehydrogenase) (20-alpha-hsd) (e2dh). [swissprot;acc:p14061]	0	11634.4	1.05864	10989.9
323	60s ribosomal protein l23a. [swissprot;acc:p29316]	1	241.884	1.09947	265.945
	ras-related c3 botulinum toxin substrate 1 (p21-rac1) (ras-like protein tc25). [swissprot;acc:p15154]	0	17387.1	1.05843	16427.3
324	40s ribosomal protein s23. [swissprot;acc:p39028]	1	243.944	1.09941	268.195
	ras-related c3 botulinum toxin substrate 3 (p21-rac3). [swissprot;acc:o14658]	0	17387.1	1.05843	16427.3
325	28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235]	1	243.944	1.09941	268.195
	mstp028 protein. [refseq;acc:nm_031954]	0	7965.66	1.05811	7528.21

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.