MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2027 to 2076 of 2158 in total

Network Comparison Type  : Subtracted
Interaction Map  : Low confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Value Type
5028	likely ortholog of mouse c-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 13; c-type lectin 13; likely ortholog of rat kupffer cell c-type lectin receptor. [refseq;acc:nm_173535]	Ranked
5029	gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]
	likely ortholog of mouse c-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 13; c-type lectin 13; likely ortholog of rat kupffer cell c-type lectin receptor. [refseq;acc:nm_173535]	Measured
		Squared
		Rooted
5030	cobw-like protein. [refseq;acc:nm_018491]	Ranked
	gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]	Measured
		Squared
		Rooted
5031	cobw-like protein. [refseq;acc:nm_018491]	Measured
		Squared
		Rooted
	tigger transposable element derived 7; jerky (mouse) homolog-like. [refseq;acc:nm_033208]	Ranked
5032	signal recognition particle 14 kda protein (srp14) (18 kda alu rna binding protein). [swissprot;acc:p37108]
	tigger transposable element derived 7; jerky (mouse) homolog-like. [refseq;acc:nm_033208]	Measured
		Squared
		Rooted
5033	rap1 gtpase-gdp dissociation stimulator 1 (smg p21 stimulatory gdp/gtp exchange protein) (smg gds protein) (exchange factor smggds). [swissprot;acc:p52306]	Ranked
	signal recognition particle 14 kda protein (srp14) (18 kda alu rna binding protein). [swissprot;acc:p37108]	Measured
		Squared
		Rooted
5034	rap1 gtpase-gdp dissociation stimulator 1 (smg p21 stimulatory gdp/gtp exchange protein) (smg gds protein) (exchange factor smggds). [swissprot;acc:p52306]	Measured
		Squared
		Rooted
	solute carrier family 21 member 15 (organic anion transporter polypeptide-related protein 4) (oatp-rp4) (oatprp4). [swissprot;acc:q9h2y9]	Ranked
5035	lipin 1. [swissprot;acc:q14693]
	solute carrier family 21 member 15 (organic anion transporter polypeptide-related protein 4) (oatp-rp4) (oatprp4). [swissprot;acc:q9h2y9]	Measured
		Squared
		Rooted
5036	lipin 1. [swissprot;acc:q14693]	Measured
		Squared
		Rooted
	lipin 3 (lipin 3-like) (fragments). [swissprot;acc:q9bqk8]	Ranked
5037		Measured
		Squared
		Rooted
	myeloblast kiaa0230 (fragment). [sptrembl;acc:q92626]	Ranked
5038		Measured
		Squared
		Rooted
	testis specific leucine rich repeat protein. [refseq;acc:nm_012472]	Ranked
5039	major centromere autoantigen b (centromere protein b) (cenp-b). [swissprot;acc:p07199]
	testis specific leucine rich repeat protein. [refseq;acc:nm_012472]	Measured
		Squared
		Rooted
5040	leucine rich repeat (in flii) interacting protein 1. [refseq;acc:nm_004735]	Ranked
	major centromere autoantigen b (centromere protein b) (cenp-b). [swissprot;acc:p07199]	Measured
		Squared
		Rooted
5041	leucine rich repeat (in flii) interacting protein 1. [refseq;acc:nm_004735]	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.