MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	Value Type	description	Network Comparison Type	Filtered	Interaction Map	green	red	network_comparison

Results: HTML CSV LaTeX

Showing element 501 to 550 of 12912 in total

Network Comparison Type  : Divided
Filtered  : 1
Interaction Map  : High confidence

Rank	Value Type	description	green	red	network_comparison
126	Measured	cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326]	18164.9	24250	1.33499
	Ranked	associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799]	114	94	1.21277
	Squared	serine/threonine protein phosphatase pp1-alpha 1 catalytic subunit (ec 3.1.3.16) (pp-1a). [swissprot;acc:p08129]	124480	189976	1.52616
	Rooted	high-mobility group 20b; sox-like transcriptional factor; swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily e, member 1-related. [refseq;acc:nm_006339]	75.1387	60.9342	1.23311
127	Measured	transcription factor jun-d. [swissprot;acc:p17535]	7523.39	5638.2	1.33436
	Ranked	putative breast adenocarcinoma marker (32kd). [refseq;acc:nm_014453]	114	94	1.21277
	Squared	cyclin-dependent kinases regulatory subunit 1 (cks-1) (sid1334) (pnas-16 / pnas-143). [swissprot;acc:p33551]	58423.3	88432.6	1.51365
	Rooted	high-mobility group 20a. [refseq;acc:nm_018200]	75.094	60.9353	1.23236
128	Measured	luc7-like 2; cgi-74 protein; cgi-59 protein. [refseq;acc:nm_016019]	5810.82	4355.61	1.3341
	Ranked	associated molecule with the sh3 domain of stam. [refseq;acc:nm_006463]	114	94	1.21277
	Squared	pnas-18. [sptrembl;acc:q9bzu3]	58155.8	87787.3	1.50952
	Rooted	tar dna-binding protein-43 (tdp-43). [swissprot;acc:q13148]	39.0445	48.0515	1.23069
129	Measured	luc7-like; sarcoplasmic reticulum protein luc7b1. [refseq;acc:nm_018032]	5811.49	4358.13	1.33348
	Ranked	neuroendocrine differentiation factor; comparative gene identification transcript 149. [refseq;acc:nm_016079]	114	94	1.21277
	Squared	pre-mrna cleavage complex ii protein pcf11 (fragment). [swissprot;acc:o94913]	118639	178263	1.50257
	Rooted	dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2]	66.7323	54.2343	1.23044
130	Measured	forkhead box p4; fork head-related protein like a; winged-helix repressor foxp4. [refseq;acc:nm_138457]	2978.53	2234.68	1.33287
	Ranked	protein hspc134 (protein cda04). [swissprot;acc:q9by43]	114	94	1.21277
	Squared	44050 protein. [refseq;acc:nm_178832]	99628.4	148058	1.4861
	Rooted	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	67.5701	55.1026	1.22626
131	Measured	forkhead box protein p1 (hspc215). [swissprot;acc:q9h334]	2978.57	2234.73	1.33285
	Ranked	son protein (son3) (negative regulatory element-binding protein) (nre- binding protein) (dbp-5) (bax antagonist selected in saccharomyces 1) (bass1) (protein c21orf50). [swissprot;acc:p18583]	242.562	294.053	1.21228
	Squared	nuclear inhibitor of protein phosphatase-1 (nipp-1) (protein phosphatase 1, regulatory inhibitor subunit 8) [includes: activator of rna decay (ec 3.1.4.-) (ard-1)]. [swissprot;acc:q12972]	99628.4	148058	1.4861
	Rooted	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]	67.5537	55.1113	1.22577
132	Measured	forkhead box protein p3 (zinc finger protein jm2) (scurfin). [swissprot;acc:q9bzs1]	2980.35	2236.61	1.33253
	Ranked	tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106]	290	350	1.2069
	Squared	autophagy protein 5-like (apg5-like) (apoptosis-specific protein). [swissprot;acc:q9h1y0]	24466.8	36359.2	1.48606
	Rooted	histone acetyltransferase type b catalytic subunit (ec 2.3.1.48). [swissprot;acc:o14929]	55.0576	44.963	1.22451
133	Measured	gaba(a) receptor-associated protein; gaba(a)-receptor-associated protein. [refseq;acc:nm_007278]	17580.4	23421.5	1.33225
	Ranked	tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616]	290	350	1.2069
	Squared	gbp protein isoform a. [refseq;acc:nm_017870]	1726.55	1182.25	1.46039
	Rooted	odd-skipped related 1; odz (odd oz/ten-m) related 1. [refseq;acc:nm_145260]	55.5995	45.4558	1.22316
134	Measured	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]	16426.1	21785.2	1.32626
	Ranked	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552]	290	350	1.2069
	Squared	p66 alpha. [refseq;acc:nm_017660]	56306.5	81888.8	1.45434
	Rooted	dna polymerase epsilon p12 subunit (dna polymerase epsilon subunit 4). [swissprot;acc:q9nr33]	54.7964	44.849	1.2218
135	Measured	apg3p; pc3-96 protein. [refseq;acc:nm_022488]	16426.1	21785.2	1.32626
	Ranked	cytoplasmic polyadenylation element binding protein 4. [refseq;acc:nm_030627]	290	350	1.2069
	Squared	transcription repressor p66 beta component of the mecp1 complex. [refseq;acc:nm_020699]	56306.5	81888.8	1.45434
	Rooted	20 kda nuclear cap binding protein (ncbp 20 kda subunit) (cbp20) (ncbp interacting protein 1) (nip1). [swissprot;acc:p52298]	66.6101	54.935	1.21253
136	Measured	nuclear transcription factor y subunit gamma (nf-y protein chain c) (nuclear factor yc) (nf-yc) (ccaat-binding transcription factor subunit c) (cbf-c) (transactivator hsm-1/2). [swissprot;acc:q13952]	4763.34	3620.77	1.31556
	Ranked	cytoplasmic polyadenylation element binding protein 3. [refseq;acc:nm_014912]	290	350	1.2069
	Squared	tyrosine aminotransferase (ec 2.6.1.5) (l-tyrosine:2-oxoglutarate aminotransferase) (tat). [swissprot;acc:p17735]	56306.5	81888.8	1.45434
	Rooted	adiponectin receptor 2. [refseq;acc:nm_024551]	50.6469	41.8357	1.21061
137	Measured	ccaat-binding transcription factor subunit b (cbf-b) (nf-y protein chain a) (nf-ya) (caat-box dna binding protein subunit a). [swissprot;acc:p23511]	4763.34	3620.77	1.31556
	Ranked	ras gtpase-activating protein ngap (ras protein activator like 1). [swissprot;acc:q9ujf2]	290	350	1.2069
	Squared	cell division protein kinase 3 (ec 2.7.1.-). [swissprot;acc:q00526]	56215.8	81606.8	1.45167
	Rooted	musashi 2 isoform a. [refseq;acc:nm_138962]	66.2416	54.9787	1.20486
138	Measured	kv channel interacting protein 1; vesicle apc-binding protein; a-type potassium channel modulatory protein 1. [refseq;acc:nm_014592]	2094.3	2755.15	1.31555
	Ranked	serine/threonine protein phosphatase 2a, catalytic subunit, alpha isoform (ec 3.1.3.16) (pp2a-alpha) (replication protein c) (rp-c). [swissprot;acc:p05323]	234.204	194.372	1.20493

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.