MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Rank	Filtered	Value Type	Interaction Map	Gene	Network Comparison Type	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 501 to 550 of 38536 in total

Network Comparison Type  : Divided

description	Rank	Filtered	Value Type	Interaction Map	red	green	network_comparison
3-hydroxyacyl-coa dehydrogenase type ii (ec 1.1.1.35) (type ii hadh) (endoplasmic reticulum-associated amyloid beta-peptide binding protein) (short-chain type dehydrogenase/reductase xh98g2). [swissprot;acc:q99714]	3180	1	Rooted	High confidence	0.00001	0.00001	1
	3728		Measured	Low confidence	7900.62	8094.29	1.02451
	3855		Rooted		71.5231	73.5484	1.02832
	4091		Ranked		202.282	200.093	1.01094
3-hydroxyanthranilate 3,4-dioxygenase (ec 1.13.11.6) (3-hao) (3-hydroxyanthranilic acid dioxygenase) (3-hydroxyanthranilate oxygenase). [swissprot;acc:p46952]	111		Squared		65044.3	74962.3	1.15248
	143		Measured		10696.6	11639.5	1.08815
	399		Rooted		84.6421	88.7007	1.04795
	1250		Ranked		180.665	176.667	1.02263
	1764		Rooted	High confidence	67.2158	69.3348	1.03153
	2105		Measured		6916.14	7295.24	1.05481
	2189		Ranked		209.54	208.162	1.00662
	2642		Squared		35558.6	36579.1	1.0287
3-hydroxyisobutyryl-coenzyme a hydrolase. [refseq;acc:nm_014362]	327	0	Ranked		9897.29	10466.5	1.05751
	376		Rooted		32.3671	31.1453	1.03923
	438		Measured		2925.57	2853.65	1.0252
	442		Rooted	Low confidence	27.2263	25.4539	1.06963
	477		Squared	High confidence	18353.1	18218.3	1.0074
	501		Ranked	Low confidence	10721.7	11352.1	1.0588
	581		Measured		2015.65	1932.95	1.04278
	646	1	Squared	High confidence	27898	32866.2	1.17808
	703	0		Low confidence	10851.4	10485.1	1.03494
	879	1	Ranked		203.354	198.284	1.02557
	1052		Rooted		71.6074	74.3827	1.03876
	1660		Measured		7966.46	8232.52	1.0334
	1852		Ranked	High confidence	196.008	198.154	1.01095
	1898		Measured		6885.11	7317.48	1.0628
	2412		Rooted		70.3295	71.371	1.01481
	3343		Squared	Low confidence	45082.7	43619.2	1.03355
3-ketoacyl-coa thiolase, peroxisomal precursor (ec 2.3.1.16) (beta- ketothiolase) (acetyl-coa acyltransferase) (peroxisomal 3-oxoacyl- coa thiolase). [swissprot;acc:p09110]	346	0	Measured	High confidence	1837.26	1721.76	1.06708
	357		Rooted		28.0711	26.8141	1.04688
	455		Squared		6970.13	6794.39	1.02587
	459		Measured	Low confidence	1616.87	1500.63	1.07746
	461		Rooted		26.1189	24.5318	1.0647
	478		Ranked	High confidence	10156.4	10243.1	1.00854
	614			Low confidence	10641.4	10984.2	1.03221
	655		Squared		5516.4	5250.39	1.05066
	1116	1		High confidence	27235.1	31125.2	1.14283
	2300		Ranked		191.563	192.541	1.00511
	2305		Measured		6946.82	7263.87	1.04564
	2490		Rooted		71.4427	72.2607	1.01145
	2649		Ranked	Low confidence	195.904	192.486	1.01776
	3780		Measured		8168.73	8366.35	1.02419
	3866		Rooted		73.8081	75.8932	1.02825
	3876		Squared		44613.5	43332.8	1.02955
3-mercaptopyruvate sulfurtransferase (ec 2.8.1.2) (mst). [swissprot;acc:p25325]	515			High confidence	19987.6	23960.7	1.19878
	563		Measured		5480.24	6222.04	1.13536
	767		Rooted		63.5181	67.7402	1.06647
	1025		Ranked		205.632	199.266	1.03195
	2218		Measured	Low confidence	8425.53	8689.87	1.03137
	2252		Ranked		196.562	192.92	1.01888

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.