Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 151 to 200 of 9634 in total
Value Type  : Ranked
Network Comparison Type  : Divided
Rank
description
Interaction Map
Filtered
red
green
network_comparison
38 microfibril-associated glycoprotein 4 precursor. [swissprot;acc:p55083] High confidence 1 322 253 1.27273
williams-beuren syndrome chromosome region 14 protein (ws basic-helix- loop-helix leucine zipper protein) (ws-bhlh) (mlx interactor). [swissprot;acc:q9np71] Low confidence 0 6768.72 9243.55 1.36563
39 blocked early in transport 1 homolog (s. cerevisiae) like; golgi snare 15 kda protein. [refseq;acc:nm_016526] 11290 8270.5 1.36509
ero1-like. [refseq;acc:nm_014584] High confidence 13853 20536 1.48242
glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] Low confidence 1 247.202 282.937 1.14456
protein phosphatase 1, regulatory subunit 14d; pkc-dependent pp1 inhibitory protein. [refseq;acc:nm_017726] High confidence 322 253 1.27273
40 ficolin 2 precursor (collagen/fibrinogen domain-containing protein 2) (ficolin-b) (ficolin b) (serum lectin p35) (ebp-37) (hucolin) (l- ficolin). [swissprot;acc:q15485]
filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333] 0 3845 5699 1.48218
glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] Low confidence 11761 15924 1.35397
son protein (son3) (negative regulatory element-binding protein) (nre- binding protein) (dbp-5) (bax antagonist selected in saccharomyces 1) (bass1) (protein c21orf50). [swissprot;acc:p18583] 1 255.382 223.538 1.14245
41 60s ribosomal protein l21. [swissprot;acc:p46778] High confidence 0 9994.33 6758.83 1.47871
ba127l20.1 (novel glutathione-s-transferase). [sptrembl;acc:q9h4y5] Low confidence 1 228.147 200.55 1.13761
nadh-ubiquinone oxidoreductase mlrq subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-mlrq) (ci-mlrq). [swissprot;acc:o00483] 0 8655 6435 1.34499
protein phosphatase 1, regulatory (inhibitor) subunit 14c; serologically defined breast cancer antigen ny-br-81; pkc-potentiated pp1 inhibitory protein. [refseq;acc:nm_030949] High confidence 1 322 253 1.27273
42 adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236] 0 8158 5530.5 1.47509
glutathione transferase omega 1 (ec 2.5.1.18) (gsto 1-1). [swissprot;acc:p78417] Low confidence 1 227.371 200.532 1.13384
mesoderm induction early response 1. [refseq;acc:nm_020948] 0 6489.72 8709.15 1.34199
proto-oncogene protein c-fos (cellular oncogene fos) (g0/g1 switch regulatory protein 7). [swissprot;acc:p01100] High confidence 1 204.641 160.957 1.2714
43 glutathione s-transferase theta 2 (ec 2.5.1.18) (gst class-theta). [swissprot;acc:p30712] 0 12143.8 8356.02 1.4533
jun dimerization protein. [refseq;acc:nm_130469] 1 204.641 160.957 1.2714
pnas-129. [sptrembl;acc:q9bxv8] Low confidence 0 11107.6 14842.4 1.33624
regulator of g-protein signaling 12 (rgs12). [swissprot;acc:o14924] 1 247.768 219.841 1.12703
44 fos-related antigen 2. [swissprot;acc:p15408] High confidence 204.641 161.046 1.2707
p28 ing5. [refseq;acc:nm_032329] Low confidence 0 12418.8 9391.47 1.32235
protein phosphatase 1, regulatory (inhibitor) subunit 14a; 17-kda pkc-potentiated inhibitory protein of pp1. [refseq;acc:nm_033256] 1 242.742 217.217 1.11751
serpin b12. [swissprot;acc:q96p63] High confidence 0 14604.2 21138.6 1.44743
45 hurpin (hacat uv-repressible serpin) (protease inhibitor 13) (headpin) (serpin b13). [swissprot;acc:q9uiv8] 14592 21113.7 1.44694
microfibril-associated glycoprotein 4 precursor. [swissprot;acc:p55083] Low confidence 1 242.742 217.217 1.11751
protein fosb (g0/g1 switch regulatory protein 3). [swissprot;acc:p53539] High confidence 204.641 161.051 1.27066
zona pellucida sperm-binding protein 3 precursor (zona pellucida glycoprotein zp3) (zona pellucida protein c) (sperm receptor) (zp3a/zp3b). [swissprot;acc:p21754] Low confidence 0 10665.2 14025.1 1.31503
46 60s ribosomal protein l37a. [swissprot;acc:p12751] High confidence 12941.7 18499.2 1.42943
fos-related antigen 1 (fra-1). [swissprot;acc:p15407] 1 204.642 161.068 1.27053
protein phosphatase 1, regulatory subunit 14d; pkc-dependent pp1 inhibitory protein. [refseq;acc:nm_017726] Low confidence 242.742 217.217 1.11751
synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296] 0 17361.7 13210.4 1.31424
47 25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528] High confidence 12941.7 18499.2 1.42943
ficolin 2 precursor (collagen/fibrinogen domain-containing protein 2) (ficolin-b) (ficolin b) (serum lectin p35) (ebp-37) (hucolin) (l- ficolin). [swissprot;acc:q15485] Low confidence 1 242.742 217.217 1.11751
gbp protein isoform a. [refseq;acc:nm_017870] High confidence 325.586 256.492 1.26938
nucleoporin nup43 (p42). [swissprot;acc:q8nfh3] Low confidence 0 4338.65 5700.79 1.31395
48 b24o18.3 (pom121 membrane glycoprotein (rat homolog)-like 2). [sptrembl;acc:q96kw2] 10664.4 14002.9 1.31305
gaba(a) receptor-associated protein; gaba(a)-receptor-associated protein. [refseq;acc:nm_007278] High confidence 1 65.4586 83.0461 1.26868
nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718] 0 9830 6909 1.42278
protein phosphatase 1, regulatory (inhibitor) subunit 14c; serologically defined breast cancer antigen ny-br-81; pkc-potentiated pp1 inhibitory protein. [refseq;acc:nm_030949] Low confidence 1 242.742 217.217 1.11751
49 bet5 homolog (multiple myeloma protein 2) (mum-2). [swissprot;acc:q9y5r8] 0 14607.1 11141.9 1.31101
beta-arrestin 2 (arrestin, beta 2). [swissprot;acc:p32121] High confidence 1 133 105 1.26667
brain protein 16. [refseq;acc:nm_016458] 0 6890.54 4854.99 1.41927
t-box transcription factor tbx19 (t-box protein 19). [swissprot;acc:o60806] Low confidence 1 225.438 202.569 1.11289
50 beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407] High confidence 133 105 1.26667
cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747] 0 9249.73 13091.4 1.41533
fructose-1,6-bisphosphatase isozyme 2 (ec 3.1.3.11) (d-fructose-1,6- bisphosphate 1-phosphohydrolase) (fbpase). [swissprot;acc:o00757] Low confidence 9449.27 12378.5 1.31
junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2] 1 234.802 260.98 1.11149

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/