Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene description Rank Value Type Network Comparison Type red Filtered Interaction Map green network_comparison

Results: HTML CSV LaTeX

Showing element 101 to 150 of 1892 in total

Network Comparison Type: Subtracted
red: 0
Filtered: 1
Interaction Map: High confidence
green: 0
network\_comparison: 0

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description\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Rank\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
Value Type\vspace{3pt}}\\
\hline
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au rna-binding protein/enoyl-coenzyme a hydratase precursor; au rna-binding protein/enoyl-coenzyme a hydratase; 3-methylglutaconyl-coa hydratase; mga type i. [source:refseq;acc:nm\_001698]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
2913\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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ba203i16.1 (hypothetical protein kiaa0970). [source:sptrembl;acc:q9h1w1]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
3117\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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ba528a10.3.2 (novel protein similar to kiaa0161, isoform 2) (fragment). [source:sptrembl;acc:q9bx39]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
2968\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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barrier-to-autointegration factor (breakpoint cluster region protein 1). [source:swissprot;acc:o75531]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
2804\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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bax inhibitor-1 (bi-1) (testis enhanced gene transcript). [source:swissprot;acc:p55061]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
2950\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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bcl-6 interacting corepressor isoform 1. [source:refseq;acc:nm\_017745]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
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beta-ureidopropionase (ec 3.5.1.6) (beta-alanine synthase) (n-carbamoyl-beta-alanine amidohydrolase) (bup-1). [source:swissprot;acc:q9ubr1]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
3145\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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bone morphogenetic protein 5 precursor (bmp-5). [source:swissprot;acc:p22003]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
3069\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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bone morphogenetic protein 6 precursor (bmp-6). [source:swissprot;acc:p22004]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
2896\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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bone morphogenetic protein 7 precursor (bmp-7) (osteogenic protein 1) (op-1). [source:swissprot;acc:p18075]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
3128\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [source:swissprot;acc:p34820]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
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brca1 associated protein. [source:refseq;acc:nm\_006768]\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
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bromodomain and phd finger-containing protein 3 (fragment). [source:swissprot;acc:q9uld4]\vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
3149\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
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Legend:
- Rank is the rank after comparing the two networks

 - Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray

 - Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.

 - Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them

 - Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.

 - Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/