Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 2900 to 2949 of 6456 in total 
Value Type	Measured
Interaction Map	High confidence
Filtered	1

Rank	description	Network Comparison Type	red	green	network_comparison	
1450	gamma-snap-associated factor 1; rab11-interacting protein. [source:refseq;acc:nm_015470]	Divided	5602.01	6031.05	1.07659	
1451	calnexin precursor (major histocompatibility complex class i antigen-binding protein p88) (p90) (ip90). [source:swissprot;acc:p27824]	Subtracted	5910.06	6355.08	445.02	
1451	neighbor of cox4. [source:swissprot;acc:o43402]	Divided	5602.01	6031.05	1.07659	
1452	protein c14orf122 (cgi-112). [source:swissprot;acc:q9y3b6]	Divided	5602.01	6031.05	1.07659	
1452	soluble liver antigen/liver pancreas antigen. [source:refseq;acc:nm_153825]	Subtracted	5910.06	6355.08	445.02	
1453	potential phospholipid-transporting atpase iia (ec 3.6.1.-). [source:swissprot;acc:o75110]	Divided	5602.01	6031.05	1.07659	
1453	rna (guanine-7-) methyltransferase. [source:refseq;acc:nm_003799]	Subtracted	5910.06	6355.08	445.02	
1454	ubiquitin-like protein sumo-1 conjugating enzyme (ec 6.3.2.19) (sumo- 1-protein ligase) (ubiquitin carrier protein) (ubiquitin-conjugating enzyme ubce2a) (p18). [source:swissprot;acc:p50550]	Divided	5770.74	6210.65	1.07623	
1454	wd-repeat protein 3. [source:swissprot;acc:q9unx4]	Subtracted	4039.81	4484.22	444.41	
1455	apoptosis-inducing factor (aif)-homologous mitochondrion-associated inducer of death; p53-responsive gene 3. [source:refseq;acc:nm_032797]	Subtracted	5945.56	6389.63	444.07	
1455	lim protein (similar to rat protein kinase c-binding enigma); enigma homolog. [source:refseq;acc:nm_006457]	Divided	5672.68	6104.68	1.07615	
1456	e1a binding protein p400; p400 swi2/snf2-related protein; cagh32 protein; trinucleotide repeat containing 12. [source:refseq;acc:nm_015409]	Divided	5672.25	6104.01	1.07612	
1456	myosin viia. [source:swissprot;acc:q13402]	Subtracted	5759.68	6203.63	443.95	
1457	collagen alpha 5(iv) chain precursor. [source:swissprot;acc:p29400]	Divided	5672.23	6103.98	1.07612	
1457	ubiquitin-conjugating enzyme e2 b (ec 6.3.2.19) (ubiquitin-protein ligase b) (ubiquitin carrier protein b) (hr6b) (hhr6b) (e2-17 kda). [source:swissprot;acc:p23567]	Subtracted	5759.68	6203.63	443.95	
1458	mitochondrial ribosomal protein l24. [source:refseq;acc:nm_024540]	Divided	5672.25	6104.01	1.07612	
1458	ubiquitin-conjugating enzyme e2 a (ec 6.3.2.19) (ubiquitin-protein ligase a) (ubiquitin carrier protein a) (hr6a) (hhr6a). [source:swissprot;acc:p49459]	Subtracted	5759.68	6203.63	443.95	
1459	65 kda yes-associated protein (yap65). [source:swissprot;acc:p46937]	Divided	5672.25	6104.01	1.07612	
1459	eif-5a2 protein. [source:refseq;acc:nm_020390]	Subtracted	6222.4	6665.83	443.43	
1460	26s proteasome non-atpase regulatory subunit 9 (26s proteasome regulatory subunit p27). [source:swissprot;acc:o00233]	Subtracted	5996.14	6439.46	443.32	
1460	p29ing4; candidate tumor suppressor p33 ing1 homolog. [source:refseq;acc:nm_016162]	Divided	5696.65	6130.26	1.07612	
1461	60 kda heat shock protein, mitochondrial precursor (hsp60) (60 kda chaperonin) (cpn60) (heat shock protein 60) (hsp-60) (mitochondrial matrix protein p1) (p60 lymphocyte protein) (hucha60). [source:swissprot;acc:p10809]	Subtracted	5457.14	5899.85	442.71	
1461	9 kda protein. [source:swissprot;acc:p13994]	Divided	5672.25	6104.01	1.07612	
1462	eukaryotic translation initiation factor 5a (eif-5a) (eif-4d) (rev- binding factor). [source:swissprot;acc:p10159]	Subtracted	6212.98	6655.12	442.14	
1462	transcriptional co-activator with pdz-binding motif (taz). [source:refseq;acc:nm_015472]	Divided	5672.24	6103.99	1.07612	
1463	collagen alpha 3(iv) chain precursor (goodpasture antigen). [source:swissprot;acc:q01955]	Divided	5672.2	6103.92	1.07611	
1463	transketolase (ec 2.2.1.1) (tk). [source:swissprot;acc:p29401]	Subtracted	5692.53	6134.64	442.11	
1464	mbd2 (methyl-cpg-binding protein)-interacting zinc finger protein. [source:refseq;acc:nm_015517]	Subtracted	4757.46	5198.91	441.45	
1464	zasp protein (fragment). [source:sptrembl;acc:q9y4z3]	Divided	5671.93	6103.49	1.07609	
1465	glycerol-3-phosphate dehydrogenase [nad+], cytoplasmic (ec 1.1.1.8) (gpd-c) (gpdh-c). [source:swissprot;acc:p21695]	Divided	5686.74	6119.36	1.07608	
1465	skeletal muscle tropomodulin (sk-tmod) (tropomodulin 4). [source:swissprot;acc:q9nzq9]	Subtracted	4757.46	5198.91	441.45	
1466	proteasome subunit beta type 5 precursor (ec 3.4.25.1) (proteasome epsilon chain) (macropain epsilon chain) (multicatalytic endopeptidase complex epsilon chain) (proteasome subunit x) (proteasome chain 6) (proteasome subunit mb1). [source:swissprot;acc:p28074]	Divided	6523.17	7019.44	1.07608	
1466	ubiquitous tropomodulin (u-tmod) (tropomodulin 3). [source:swissprot;acc:q9nyl9]	Subtracted	4757.46	5198.91	441.45	
1467	p47 protein isoform a. [source:refseq;acc:nm_016143]	Divided	6444.4	6932.39	1.07572	
1467	tropomodulin 1 (erythrocyte tropomodulin) (e-tmod). [source:swissprot;acc:p28289]	Subtracted	4757.46	5198.91	441.45	
1468	sorting nexin 9 (sh3 and px domain-containing protein 1) (sdp1 protein). [source:swissprot;acc:q9y5x1]	Subtracted	4757.46	5198.91	441.45	
1468	sphingosine-1-phosphate lyase 1; sphingosine-1-phosphate lyase. [source:refseq;acc:nm_003901]	Divided	5473.09	5887.45	1.07571	
1469	4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [source:swissprot;acc:p80404]	Divided	5473.09	5887.45	1.07571	
1469	neuronal tropomodulin (n-tmod) (tropomodulin 2). [source:swissprot;acc:q9nzr1]	Subtracted	4757.46	5198.91	441.45	
1470	homeobox protein dlx-2. [source:swissprot;acc:q07687]	Subtracted	4757.46	5198.91	441.45	
1470	ornithine aminotransferase, mitochondrial precursor (ec 2.6.1.13) (ornithine--oxo-acid aminotransferase). [source:swissprot;acc:p04181]	Divided	5473.09	5887.45	1.07571	
1471	40s ribosomal protein s8. [source:swissprot;acc:p09058]	Divided	5659.45	6087.55	1.07564	
1471	homeobox protein dlx-5. [source:swissprot;acc:p56178]	Subtracted	4757.46	5198.91	441.45	
1472	26s proteasome non-atpase regulatory subunit 6 (26s proteasome regulatory subunit s10) (p42a) (proteasome regulatory particle subunit p44s10). [source:swissprot;acc:q15008]	Divided	5984.47	6435.42	1.07535	
1472	fetal brain protein 239 (239fb). [source:swissprot;acc:q15777]	Subtracted	4757.46	5198.91	441.45	
1473	calmegin precursor. [source:swissprot;acc:o14967]	Divided	5910.06	6355.08	1.0753	
1473	homeobox protein dlx-3. [source:swissprot;acc:o60479]	Subtracted	4757.46	5198.91	441.45	
1474	activated p21cdc42hs kinase. [source:refseq;acc:nm_005781]	Subtracted	4757.46	5198.91	441.45	
1474	calnexin precursor (major histocompatibility complex class i antigen-binding protein p88) (p90) (ip90). [source:swissprot;acc:p27824]	Divided	5910.06	6355.08	1.0753	
1475	mitogen-activated protein kinase kinase kinase 7 interacting protein 2 isoform 1; tak1-binding protein 2. [source:refseq;acc:nm_015093]	Subtracted	4757.46	5198.91	441.45	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/