MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Network Comparison Type	Gene	Hugo	description	Value Type	Interaction Map	Filtered	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 794 to 843 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
network_comparison  : 0
red  : 0
green  : 0

Rank	Hugo	description	Value Type
2954	NDUFA9	nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795]	Ranked
			Squared
			Rooted
2955	FBN2	fibrillin 2 precursor. [swissprot;acc:p35556]	Measured
			Ranked
			Squared
			Rooted
2956	SEC24B	protein transport protein sec24b (sec24-related protein b). [swissprot;acc:o95487]	Measured
			Ranked
			Squared
			Rooted
2957	ENPEP	glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]	Measured
			Ranked
			Squared
			Rooted
2958	CNOT6L	ccr4-not transcription complex, subunit 6-like. [refseq;acc:nm_144571]	Measured
			Ranked
			Squared
			Rooted
2959	no value	60s ribosomal protein l37a. [swissprot;acc:p12751]	Measured
			Ranked
			Squared
			Rooted
2960	AOX1	aldehyde oxidase (ec 1.2.3.1). [swissprot;acc:q06278]	Measured
			Ranked
			Squared
			Rooted
2961	RAB1A	ras-related protein rab-1a (ypt1-related protein). [swissprot;acc:p11476]	Measured
			Ranked
			Squared
			Rooted
2962	DYNC2LI1	dynein 2 light intermediate chain. [refseq;acc:nm_016008]	Measured
			Ranked
			Squared
			Rooted
2963	RABGGTB	geranylgeranyl transferase type ii beta subunit (ec 2.5.1.-) (rab geranylgeranyltransferase beta subunit) (rab geranyl- geranyltransferase beta subunit) (rab gg transferase beta) (rab ggtase beta). [swissprot;acc:p53611]	Measured
			Ranked
			Squared
			Rooted
2964	SEMA6D	semaphorin 6d isoform 3 precursor. [refseq;acc:nm_153617]	Measured
			Ranked
			Squared
			Rooted
2965	SLCO5A1	solute carrier family 21 member 15 (organic anion transporter polypeptide-related protein 4) (oatp-rp4) (oatprp4). [swissprot;acc:q9h2y9]	Measured
			Ranked
			Squared
			Rooted
2966	PI15	protease inhibitor 15 preproprotein; 25 kda trypsin inhibitor. [refseq;acc:nm_015886]	Measured
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.