MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	description	Filtered	Network Comparison Type	Interaction Map	Rank	Value Type	green	network_comparison	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

description	Filtered	Interaction Map	Rank	Value Type	green	network_comparison	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	0	High confidence	37	Measured	934.348	2.79409	334.401
				Squared	1034.13	10.2338	101.05
			53	Rooted	18.0183	1.5213	11.844
			242	Ranked	13895.8	1.09822	15260.6
		Low confidence	131	Measured	851.77	1.31954	645.504
			146	Squared	1268.51	1.63527	775.72
			537	Rooted	17.0804	1.04801	16.298
			629	Ranked	13590.3	1.02915	13205.3
	1	High confidence	18		245.247	1.32082	185.678
			60	Measured	2765.82	1.6231	4489.19
			64	Rooted	47.2654	1.35128	63.8686
			245	Squared	6768.05	1.31131	8875.01
		Low confidence	1119		41688.5	1.04654	43628.5
			4130	Ranked	201.5	1.01062	199.383
			4914	Measured	7900.54	1.00597	7853.62
				Rooted	72.6287	1.00944	71.9496
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]		High confidence	295	Squared	39351.7	1.27733	30807.7
			509	Measured	8630.06	1.14278	7551.8
			805	Rooted	79.1513	1.0645	74.3557
			1038	Ranked	181.041	1.03148	186.741
		Low confidence	885	Measured	8585.64	1.03993	8255.95
			1092	Rooted	76.3375	1.0386	73.5001
			1328	Ranked	194.038	1.02218	198.342
			4562	Squared	45736	1.01928	46617.7
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]		High confidence	294		39383.9	1.2776	30826.5
			508	Measured	8636.87	1.14293	7556.75
			804	Rooted	79.1931	1.0646	74.3877
			1032	Ranked	180.943	1.03162	186.664
		Low confidence	880	Measured	8587.03	1.04001	8256.68
			1084	Rooted	76.3467	1.03863	73.5068
			1322	Ranked	194.014	1.0222	198.322
			4569	Squared	45740.5	1.01914	46616.1
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]		High confidence	311		38866.5	1.27154	30566.4
			514	Measured	8532.02	1.1411	7477
			822	Rooted	78.5795	1.06393	73.8577
			1048	Ranked	182.308	1.031	187.96
		Low confidence	237	Measured	9081.29	1.06457	8530.51
			378	Rooted	79.5804	1.04871	75.8843
			588	Ranked	185.859	1.03039	191.507
			4138	Squared	47372.8	1.02676	46138.2
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]		High confidence	308		38919.9	1.27205	30596.2
			513	Measured	8543.66	1.14143	7485.08
			811	Rooted	78.6514	1.06415	73.9102
			1043	Ranked	182.137	1.03128	187.834
		Low confidence	252	Measured	9018.94	1.06194	8492.92
			427	Rooted	79.1997	1.04731	75.6219
			637	Ranked	186.751	1.029	192.166
			4418	Squared	47088.3	1.02256	46049.4
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]			2035	Measured	8323.04	1.03199	8065.05
			2766	Rooted	74.9741	1.03282	72.5914

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.