Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered green description network_comparison Gene Value Type Interaction Map red Rank Network Comparison Type
Results: HTML CSV LaTeX Showing element 951 to 1000 of 77072 in total
Filtered  : 0
green
description
network_comparison
Value Type
Interaction Map
red
Rank
Network Comparison Type
12.1701 signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556] 0.3373 Rooted High confidence 12.5074 455 Subtracted
1.02772 432 Divided
12.1722 mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476] 1.3321 9.13761 86
Low confidence 89
3.03459 High confidence 170 Subtracted
Low confidence 272
12.2043 transcription factor bteb4 (basic transcription element binding- protein 4) (bte-binding protein 4) (krueppel-like factor 16) (novel sp1-like zinc finger transcription factor 2) (transcription factor nslp2). [swissprot;acc:q9bxk1] 1.15882 10.5317 165 Divided
1.6726 432 Subtracted
12.2755 amiloride-sensitive sodium channel gamma-subunit (epithelial na+ channel gamma subunit) (gamma enac) (nonvoltage-gated sodium channel 1 gamma subunit) (scneg) (gamma nach). [swissprot;acc:p51170] 0.4846 11.7909 711
1.0411 570 Divided
12.2759 amiloride-sensitive cation channel 3 isoform a; testis sodium channel 1; proton-gated cation channel subunit; modulatory subunit of asic2a; amiloride-sensitive cation channel 3, testis. [refseq;acc:nm_004769] 0.4852 11.7907 710 Subtracted
1.04115 569 Divided
12.2882 nanos (fragment). [sptrembl;acc:q8wy41] 1.58009 High confidence 19.4165 51
7.1283 57 Subtracted
selenide,water dikinase 2 (ec 2.7.9.3) (selenophosphate synthetase 2) (selenium donor protein 2). [swissprot;acc:q99611] 1.44818 8.48528 60 Divided
Low confidence 63
3.80292 High confidence 144 Subtracted
Low confidence 225
12.2937 syntaxin 1a (neuron-specific antigen hpc-1). [swissprot;acc:q16623] 1.90407 Squared High confidence 6.45653 120 Divided
5.83717 406 Subtracted
12.3076 solute carrier family 26, member 11. [refseq;acc:nm_173626] 1.27875 Rooted Low confidence 15.7383 106 Divided
3.4307 244 Subtracted
12.3132 alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [swissprot;acc:q9nvd7] 1.35362 16.6674 80 Divided
4.3542 189 Subtracted
12.3994 amiloride-sensitive sodium channel delta-subunit (epithelial na+ channel delta subunit) (delta enac) (nonvoltage-gated sodium channel 1 delta subunit) (scned) (delta nach). [swissprot;acc:p51172] 0.6538 11.7456 660
1.05566 498 Divided
12.4394 secreted modular calcium-binding protein 1. [refseq;acc:nm_022137] 0.4918 High confidence 11.9476 432 Subtracted
Low confidence 708
1.04116 High confidence 372 Divided
Low confidence 568
12.4629 pepsin a precursor (ec 3.4.23.1). [swissprot;acc:p00790] 0.0399 High confidence 12.5028 488 Subtracted
1.0032 487 Divided
12.49 succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial precursor (cybs) (succinate-ubiquinone reductase membrane anchor subunit) (qps2) (cii-4) (succinate dehydrogenase complex subunit d) (succinate-ubiquinone oxidoreductase cytochrome b small subunit). [swissprot;acc:o14521] 3.94968 3.16228 22
9.32772 34 Subtracted
12.5026 40s ribosomal protein s28. [swissprot;acc:p25112] 1.0586 13.5612 368
1.08467 285 Divided
12.5624 dystrophin. [swissprot;acc:p11532] 7.83299 Squared 98.4011 41
85.8387 290 Subtracted
12.5698 ptd016 protein. [refseq;acc:nm_016125] 2.29492 Rooted 5.47723 30 Divided
Low confidence 17
7.09257 High confidence 58 Subtracted
Low confidence 30
12.6095 dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2] 1.43581 High confidence 18.1049 63 Divided
5.4954 85 Subtracted
12.6188 zona pellucida sperm-binding protein 3 precursor (zona pellucida glycoprotein zp3) (zona pellucida protein c) (sperm receptor) (zp3a/zp3b). [swissprot;acc:p21754] 2.13426 Squared Low confidence 26.9318 99 Divided
14.313 744 Subtracted
12.6735 alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279] 1.119 Rooted 14.1816 221 Divided
1.5081 466 Subtracted
12.7302 b24o18.3 (pom121 membrane glycoprotein (rat homolog)-like 2). [sptrembl;acc:q96kw2] 2.12849 Squared 27.0961 101 Divided
14.3659 743 Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/