Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered green network_comparison Gene Rank red description Network Comparison Type Value Type Interaction Map
Results: HTML CSV LaTeX Showing element 601 to 650 of 77072 in total
Filtered  : 0
green
network_comparison
Rank
red
description
Network Comparison Type
Value Type
Interaction Map
6.55744 6.55744 65 0 sedlin. [swissprot;acc:o14582] Subtracted Rooted High confidence
66 synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
655744 11 0.00001 sedlin. [swissprot;acc:o14582] Divided
12 synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
6.80523 1.35766 74 5.01247 high-glucose-regulated protein 8 (ny-ren-2 antigen). [swissprot;acc:q9y5a9]
75 sh3 adapter protein spin90 (sh3 protein interacting with nck, 90 kda) (vaca-interacting protein, 54 kda) (vip54) (af3p21) (diaphanous protein interacting protein) (dia interacting protein-1) (dip-1). [swissprot;acc:q9nzq3]
1.79276 291 high-glucose-regulated protein 8 (ny-ren-2 antigen). [swissprot;acc:q9y5a9] Subtracted
292 sh3 adapter protein spin90 (sh3 protein interacting with nck, 90 kda) (vaca-interacting protein, 54 kda) (vip54) (af3p21) (diaphanous protein interacting protein) (dia interacting protein-1) (dip-1). [swissprot;acc:q9nzq3]
6.85565 1.7443 29 11.9583 glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] Divided Low confidence
44 High confidence
5.10265 62 Subtracted Low confidence
91 High confidence
5.38516 21 36.9188 adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61] Divided
30.0631 3 Subtracted
6.91035 1.38378 216 9.56237 high-glucose-regulated protein 8 (ny-ren-2 antigen). [swissprot;acc:q9y5a9] Divided Squared
217 sh3 adapter protein spin90 (sh3 protein interacting with nck, 90 kda) (vaca-interacting protein, 54 kda) (vip54) (af3p21) (diaphanous protein interacting protein) (dia interacting protein-1) (dip-1). [swissprot;acc:q9nzq3]
2.65202 430 high-glucose-regulated protein 8 (ny-ren-2 antigen). [swissprot;acc:q9y5a9] Subtracted
431 sh3 adapter protein spin90 (sh3 protein interacting with nck, 90 kda) (vaca-interacting protein, 54 kda) (vip54) (af3p21) (diaphanous protein interacting protein) (dia interacting protein-1) (dip-1). [swissprot;acc:q9nzq3]
6.95259 1.26588 110 8.80111 blood group rh(d) polypeptide (rhesus d antigen) (rhxiii) (rh polypeptide 2) (rhpii). [swissprot;acc:q02161] Divided Rooted Low confidence
111 blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577]
1.84852 385 blood group rh(d) polypeptide (rhesus d antigen) (rhxiii) (rh polypeptide 2) (rhpii). [swissprot;acc:q02161] Subtracted
386 blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577]
6.95553 1.26597 109 8.80551 Divided
1.84998 384 Subtracted
6.96286 1.58452 50 11.0328 importin 7; ran-binding protein 7. [refseq;acc:nm_006391] Divided High confidence
4.06994 126 Subtracted
6.96791 1.25192 114 8.7233 laminin beta-1 chain precursor (laminin b1 chain). [swissprot;acc:p07942] Divided Low confidence
1.75539 401 Subtracted
6.97663 1.92709 38 3.62029 spir-2 protein (fragment). [sptrembl;acc:q8wwl2] Divided High confidence
3.35634 157 Subtracted
7.07107 1.29099 100 5.47723 transcription initiation factor iie, beta subunit (tfiie-beta). [swissprot;acc:p29084] Divided Low confidence
106 High confidence
1.59384 307 Subtracted
444 Low confidence
7.14143 0.21323 462 6.9282 melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801] High confidence
463 melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]
464 melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]
465 melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]
466 hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]
467 melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]
468 melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]
469 melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]
470 melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]
471 melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]
472 melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]
473 melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]
474 melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]
475 melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]
476 melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]
477 melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/