MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	network_comparison	green	Gene	Interaction Map	Value Type	Network Comparison Type	red	Rank	description

Results: HTML CSV LaTeX

Showing element 601 to 650 of 77072 in total

Filtered  : 0
Network Comparison Type  : Divided

network_comparison	green	Interaction Map	Value Type	red	Rank	description
1.00094	24.4079	High confidence	Rooted	24.4309	490	arsenical pump-driving atpase (ec 3.6.3.16) (arsenite-translocating atpase) (arsenical resistance atpase) (arsenite-transporting atpase) (arsa) (asna-i). [swissprot;acc:o43681]
	2668.83	Low confidence	Ranked	2671.33	832	vps10 domain-containing receptor sorcs1 precursor (hsorcs). [swissprot;acc:q8wy21]
	11872.8			11861.6	831	signal recognition particle receptor alpha subunit (sr-alpha) (docking protein alpha) (dp-alpha). [swissprot;acc:p08240]
1.00101	2873.96	High confidence	Squared	2871.07	491	probable calcium-transporting atpase kiaa0703 (ec 3.6.3.8). [swissprot;acc:o75185]
	15881.6	Low confidence		15865.5	833	microtubule-associated protein, rp/eb family, member 2; t-cell activation protein, eb1 family; apc-binding protein eb1. [refseq;acc:nm_014268]
1.00108	3022.35			3025.6	832	dj850e9.1 (novel c2h2 type zinc finger protein similar to drosophila scratch (scrt), slug and xenopus snail) (fragment). [sptrembl;acc:q9nq03]
1.00111	25.883		Rooted	25.9117	830	forkhead box protein j1 (forkhead-related protein fkhl13) (hepatocyte nuclear factor 3 forkhead homolog 4) (hfh-4). [swissprot;acc:q92949]
1.00123	9069.58	High confidence	Ranked	9080.73	499	inosine-5'-monophosphate dehydrogenase 2 (ec 1.1.1.205) (imp dehydrogenase 2) (impdh-ii) (impd 2). [swissprot;acc:p12268]
1.00124	28.6975	Low confidence	Rooted	28.733	829	ran-binding protein 2-like 1 isoform 2; sperm membrane protein bs-63; ran-binding protein 2-like 1. [refseq;acc:nm_032260]
	1464.85		Measured	1463.03	828	nascent-polypeptide-associated complex alpha polypeptide. [refseq;acc:nm_005594]
1.00128	22.9676	High confidence	Rooted	22.997	489	glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (ec 2.6.1.16) (hexosephosphate aminotransferase 1) (d-fructose-6- phosphate amidotransferase 1) (gfat 1) (gfat1). [swissprot;acc:q06210]
	27.3392	Low confidence		27.3043	828	ribosomal protein s27-like protein; 40s ribosomal protein s27 isoform. [refseq;acc:nm_015920]
1.0013	1673.2		Measured	1675.38	827	swi/snf-related matrix-associated actin-dependent regulator of chromatin c2 isoform a; mammalian chromatin remodeling complex brg1-associated factor 170; chromatin remodeling complex baf170 subunit; swi3-like protein; swi/snf complex 170 kda subunit. [refseq;acc:nm_003075]
1.00133	12881.3		Ranked	12864.2	830	scratch; scratch 1. [refseq;acc:nm_031309]
1.00138	14901.7		Measured	14922.2	826	heparan sulfate 6-o-sulfotransferase 2. [refseq;acc:nm_147174]
1.00147	28.8142		Rooted	28.7719	827	dj408b20.3 (novel protein similar to 60s acidic ribosomal protein p2 (rplp2)). [sptrembl;acc:q9h5a9]
1.00149	11085.2		Ranked	11101.7	829	actin, cytoplasmic 2 (gamma-actin). [swissprot;acc:p02571]
1.00153	1594.85		Measured	1597.29	825	myosin heavy chain, skeletal muscle, adult 1 (myosin heavy chain iix/d) (myhc-iix/d). [swissprot;acc:p12882]
1.00157	1595.05			1597.55	824	myosin heavy chain, skeletal muscle, fetal (myosin heavy chain iib) (myhc-iib). [swissprot;acc:q9y623]
1.00159	1595.12			1597.66	823	myosin heavy chain, skeletal muscle, adult 2 (myosin heavy chain iia) (myhc-iia). [swissprot;acc:q9ukx2]
	5046.33	High confidence		5038.33	492	3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]
		Low confidence			822
1.0016	10313.3		Squared	10296.8	831	glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]
1.00161	770.408		Measured	771.651	821	alanine aminotransferase (ec 2.6.1.2) (glutamic--pyruvic transaminase) (gpt) (glutamic--alanine transaminase). [swissprot;acc:p24298]
	10248.3	High confidence	Ranked	10231.8	498	adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]
	13860.3	Low confidence		13838	828	lactotransferrin precursor (lactoferrin) [contains: lactoferroxin a; lactoferroxin b; lactoferroxin c]. [swissprot;acc:p02788]
1.00168	8221.19			8207.37	827	mitogen-activated protein kinase kinase kinase 5 (ec 2.7.1.-) (mapk/erk kinase kinase 5) (mek kinase 5) (mekk 5) (apoptosis signal- regulating kinase 1) (ask-1). [swissprot;acc:q99683]
1.00169	31.685		Rooted	31.7384	826	histone h1.4 (histone h1b). [swissprot;acc:p10412]
1.00173	11255.5		Ranked	11236.1		transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
1.00175	82808.3		Squared	82664	830	transketolase-like 1 (ec 2.2.1.1) (transketolase 2) (tk 2) (transketolase related protein). [swissprot;acc:p51854]
1.00179	22.8963		Rooted	22.8553	825	ba395l14.12 (novel protein similar to small nuclear ribonucleoprotein polypeptide a' (snrpa1)). [sptrembl;acc:q9nu36]
1.00181	11854.2		Ranked	11832.8		26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]
1.00182	26.3602		Rooted	26.3124	824	my016 protein. [sptrembl;acc:q9h3k6]
	1595.89		Measured	1598.8	820	myosin heavy chain, skeletal muscle, extraocular (myhc-eo). [swissprot;acc:q9ukx3]
1.00184	20.9563		Rooted	20.9948	823	dead-box protein. [refseq;acc:nm_018665]
1.00185	12035.6		Ranked	12057.9	824	transcription factor btf3 homolog 3. [swissprot;acc:q13892]
1.00186	9411.49	High confidence		9394	496	vacuolar atp synthase subunit g 2 (ec 3.6.3.14) (v-atpase g subunit 2) (vacuolar proton pump g subunit 2) (v-atpase 13 kda subunit 2). [swissprot;acc:o95670]
	13718.2			13692.7	497	sh2 domain binding protein 1; tpr-containing, sh2-binding phosphoprotein. [refseq;acc:nm_014633]
1.00189	11194.8	Low confidence		11173.7	821	cell adhesion molecule with homology to l1cam precursor; neural cell adhesion molecule; cell adhesion molecule l1-like; l1 cell adhesion molecule 2. [refseq;acc:nm_006614]
					822	neural cell adhesion molecule l1 precursor (n-cam l1) (cd171 antigen). [swissprot;acc:p32004]
					823	transcription initiation factor tfiid 31 kda subunit (tafii-31) (tafii-32) (tafii32). [swissprot;acc:q16594]
1.00194	4459.15		Measured	4467.8	819	homer, neuronal immediate early gene, 1b. [refseq;acc:nm_004272]
1.00195	11119.5		Ranked	11097.9	820	importin 7; ran-binding protein 7. [refseq;acc:nm_006391]
	11748.1	High confidence		11725.2	495	26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232]
1.002	11256.8	Low confidence		11234.3	819	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
1.00201	25.3889	High confidence	Rooted	25.44	488	dj470l14.3 (novel protein similar to the arp2/3 protein complex subunit p21-arc (arc21)). [sptrembl;acc:q9h5b6]
1.00202	25.8508	Low confidence		25.9029	822	forkhead box protein f1 (forkhead-related protein fkhl5) (forkhead- related transcription factor 1) (freac-1) (forkhead-related activator- 1). [swissprot;acc:q12946]
1.00204	12210.9		Squared	12186.1	829	histone h2b.c (h2b/c). [swissprot;acc:q99880]
1.0021	3221.55	High confidence		3228.32	490	dna-directed rna polymerase i 16 kda polypeptide (ec 2.7.7.6) (rpa16). [swissprot;acc:q9y2s0]
1.00218	11959.4		Ranked	11985.5	494	signal recognition particle receptor alpha subunit (sr-alpha) (docking protein alpha) (dp-alpha). [swissprot;acc:p08240]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.