MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	description	Rank	Filtered	Value Type	Interaction Map	Network Comparison Type	green	red	network_comparison

Results: HTML CSV LaTeX

Showing element 601 to 650 of 77072 in total

description	Rank	Filtered	Value Type	Interaction Map	Network Comparison Type	green	red	network_comparison
26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232]	495	0	Ranked	High confidence	Divided	11748.1	11725.2	1.00195
	591		Squared	Low confidence		14694	15800.9	1.07533
	658		Ranked		Subtracted	11538	11801.6	263.6
	665				Divided			1.02285
	728		Rooted			26.5693	26.1642	1.01548
	730				Subtracted			0.4051
	750		Measured			2331.31	2349.9	18.59
	785				Divided			1.00797
	933	1			Subtracted	8671.34	8358.82	312.52
	1073				Divided			1.03739
	1248		Squared	High confidence	Subtracted	29539	26551.2	2987.8
	1541				Divided			1.11253
	1579		Measured			6261.87	5842.44	1.07179
	1633				Subtracted			419.43
	2042		Rooted			63.9809	62.309	1.6719
	2045				Divided			1.02683
	2154			Low confidence	Subtracted	76.2257	73.7276	2.4981
	2300		Ranked	High confidence		218.311	217.241	1.07
	2316				Divided			1.00493
	2398		Rooted	Low confidence		76.2257	73.7276	1.03388
	3393		Ranked			195.526	198.522	1.01532
	3428				Subtracted			2.996
	4889		Squared			47728.1	48009.9	281.8
	4914				Divided			1.0059
26s proteasome non-atpase regulatory subunit 13 (26s proteasome regulatory subunit s11) (26s proteasome regulatory subunit p40.5). [swissprot;acc:q9unm6]	1265			High confidence	Subtracted	29658.6	26688.8	2969.8
	1570				Divided			1.11128
	1585		Measured			6278.32	5858.48	1.07166
	1632				Subtracted			419.84
	1795			Low confidence		8388.54	8126.5	262.04
	1982				Divided			1.03225
	2033		Rooted	High confidence	Subtracted	64.07	62.382	1.688
	2038				Divided			1.02706
	2324		Ranked		Subtracted	218.116	217.112	1.004
	2329				Divided			1.00462
	2363		Rooted	Low confidence	Subtracted	75.0454	72.5927	2.4527
	2429				Divided			1.03379
	2798		Ranked			197.228	200.64	1.0173
	2828				Subtracted			3.412
	4046		Squared			45129.7	46320.5	1190.8
	4156				Divided			1.02639
26s proteasome non-atpase regulatory subunit 2 (26s proteasome regulatory subunit s2) (26s proteasome subunit p97) (tumor necrosis factor type 1 receptor associated protein 2) (55.11 protein). [swissprot;acc:q13200]	986		Measured	High confidence	Subtracted	6980.13	6436.19	543.94
	1014		Squared			34111.1	30653.9	3457.2
	1241		Measured		Divided	6980.13	6436.19	1.08451
	1331		Rooted		Subtracted	68.0886	65.478	2.6106
	1395				Divided			1.03987
	1538		Squared			34111.1	30653.9	1.11278
	1853		Measured	Low confidence	Subtracted	8521.25	8260.81	260.44
	1918		Ranked		Divided	195.527	199.382	1.01972
	1975				Subtracted			3.855
	2166		Rooted			75.7848	73.2904	2.4944

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.