Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Value Type Gene Filtered Network Comparison Type red Rank Interaction Map green network_comparison description
Results: HTML CSV LaTeX Showing element 551 to 600 of 19268 in total
Value Type  : Ranked
Filtered  : 0
Network Comparison Type  : Divided
red
Rank
Interaction Map
green
network_comparison
description
10680.4 633 Low confidence 10983.9 1.02842 survival motor neuron protein (component of gems 1) (gemin1). [swissprot;acc:q16637]
810 10637.6 1.00402 60s ribosomal protein l10a (csa-19). [swissprot;acc:p53025]
10686 285 High confidence 9925.58 1.07661 dj408b20.3 (novel protein similar to 60s acidic ribosomal protein p2 (rplp2)). [sptrembl;acc:q9h5a9]
10693.9 329 Low confidence 11839.1 1.10709 dimethylaniline monooxygenase [n-oxide forming] 3 (ec 1.14.13.8) (hepatic flavin-containing monooxygenase 3) (fmo 3) (dimethylaniline oxidase 3) (fmo form 2) (fmo ii). [swissprot;acc:p31513]
10694.8 524 11262.9 1.05312 40s ribosomal protein s26. [swissprot;acc:p02383]
10696.7 711 10513.7 1.01741 60s ribosomal protein l7. [swissprot;acc:p18124]
10720.7 142 12382.9 1.15505 zinc finger protein 183-like 1. [refseq;acc:nm_178861]
10720.9 545 11239.5 1.04837 brain protein 16. [refseq;acc:nm_016458]
10721.7 501 11352.1 1.0588 3-hydroxyisobutyryl-coenzyme a hydrolase. [refseq;acc:nm_014362]
10735.1 270 High confidence 9891.37 1.0853 ethanolamine-phosphate cytidylyltransferase (ec 2.7.7.14) (phosphorylethanolamine transferase) (ctp:phosphoethanolamine cytidylyltransferase). [swissprot;acc:q99447]
271 myosin light chain 1, embryonic muscle/atrial isoform (pro1957). [swissprot;acc:p12829]
10736.2 653 Low confidence 10485.5 1.02391 similar to ribosomal protein, large, p0. [sptrembl;acc:q96fq9]
10741.6 276 High confidence 9922.33 1.08257 60s ribosomal protein l9. [swissprot;acc:p32969]
10749.1 669 Low confidence 10515.3 1.02223 block 23. [sptrembl;acc:q8nhw5]
10750 381 11678.8 1.0864 dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2]
10751 78 13236 1.23114 histone-lysine n-methyltransferase, h3 lysine-79 specific (ec 2.1.1.43) (histone h3-k79 methyltransferase) (h3-k79-hmtase) (dot1-like protein). [swissprot;acc:q8tek3]
10760 709 10573 1.01769 sodium/hydrogen exchanger 6 (na(+)/h(+) exchanger 6) (nhe-6). [swissprot;acc:q92581]
10767.1 777 10855.5 1.00821 filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]
10768.5 316 High confidence 11444 1.06273 dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]
10771.7 148 Low confidence 9368.39 1.14979 dj681n20.2 (novel protein similar to ferritin, light polypeptide (ftl)). [sptrembl;acc:q9byw6]
10775.5 788 10700.6 1.007 galectin-4 (lactose-binding lectin 4) (l-36 lactose binding protein) (l36lbp) (antigen ny-co-27). [swissprot;acc:p56470]
10783 275 High confidence 11674.1 1.08264 cleavage and polyadenylation specificity factor, 160 kda subunit (cpsf 160 kda subunit). [swissprot;acc:q10570]
10793.5 67 14291.5 1.32408 presenilin enhancer 2; hematopoietic stem/progenitor cells protein mds033. [refseq;acc:nm_172341]
10808.3 729 Low confidence 10653.8 1.0145 40s ribosomal protein s29. [swissprot;acc:p30054]
10819.8 713 10636 1.01728 dyskerin (nucleolar protein nap57) (cbf5 homolog). [swissprot;acc:o60832]
10831.3 765 10928.4 1.00896 limbic system-associated membrane protein precursor (lsamp). [swissprot;acc:q13449]
10833.3 384 High confidence 11244.5 1.03796 bystin. [swissprot;acc:q13895]
10836.1 664 Low confidence 10593.8 1.02287 60s ribosomal protein l9. [swissprot;acc:p32969]
10844 276 9553.77 1.13505 u2 small nuclear ribonucleoprotein auxiliary factor 35 kda subunit related-protein 1. [swissprot;acc:q15695]
10851 580 11301.8 1.04154 60s acidic ribosomal protein p1. [swissprot;acc:p05386]
10854.8 417 High confidence 10537.9 1.03007 limbic system-associated membrane protein precursor (lsamp). [swissprot;acc:q13449]
10865 745 Low confidence 10994.9 1.01196 eukaryotic initiation factor 4a-like nuk-34. [swissprot;acc:p38919]
10871 682 11087.2 1.01989 histone h1.4 (histone h1b). [swissprot;acc:p10412]
10878.1 636 10584 1.02779 adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]
10878.7 503 11516.1 1.05859 neurofibromin (neurofibromatosis-related protein nf-1) [contains: neurofibromin truncated]. [swissprot;acc:p21359]
10881.2 606 11258.1 1.03464 ubiquinol-cytochrome c reductase complex core protein i, mitochondrial precursor (ec 1.10.2.2). [swissprot;acc:p31930]
10883 154 High confidence 12622.8 1.15986 myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1]
10885.2 621 Low confidence 11216.4 1.03043 crooked neck-like protein 1 (crooked neck homolog) (hcrn) (cgi-201) (mstp021). [swissprot;acc:q9bzj0]
10889.4 5 19873 1.82499 ubiquitously transcribed y chromosome tetratricopeptide repeat protein (ubiquitously transcribed tpr protein on the y chromosome). [swissprot;acc:o14607]
10897 328 High confidence 11520 1.05717 putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37]
10899.4 229 9878.1 1.10339 poly (adp-ribose) glycohydrolase. [refseq;acc:nm_003631]
10899.5 193 12217.4 1.12091 transcription factor iiia (factor a) (tfiiia). [swissprot;acc:q92664]
10900 642 Low confidence 10624.5 1.02593 dj153g14.2 (possible ca binding protein similar to nefa) (fragment). [sptrembl;acc:q9ujn8]
10904.8 431 11727.1 1.07541 butyrate-induced transcript 1. [refseq;acc:nm_016395]
10911.1 382 11853.8 1.0864 far upstream element-binding protein; far upstream element binding protein; fuse-binding protein. [refseq;acc:nm_003902]
10922.9 291 High confidence 11731.8 1.07406
10929 486 Low confidence 11592.3 1.06069 pyrroline-5-carboxylate reductase (ec 1.5.1.2) (p5cr) (p5c reductase). [swissprot;acc:p32322]
10935 145 12622.6 1.15433 metaxin 1. [swissprot;acc:q13505]
10952.3 330 12125.1 1.10708 glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]
10962.4 564 11452 1.04466 60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/