Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Value Type Rank description Interaction Map Network Comparison Type network_comparison Filtered red green
Results: HTML CSV LaTeX Showing element 551 to 600 of 19268 in total
Value Type  : Measured
Rank
description
Interaction Map
Network Comparison Type
network_comparison
Filtered
red
green
69 tubulointerstitial nephritis antigen. [refseq;acc:nm_014464] Low confidence Divided 1.82979 0 129 70.5
zinc finger protein 223. [swissprot;acc:q9uk11] Subtracted 383.13 2354.34 1971.21
70 amp deaminase 2 (ec 3.5.4.6) (amp deaminase isoform l). [swissprot;acc:q01433] High confidence Divided 1.59177 1 6475.5 10307.5
beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938] Subtracted 431 0 570 139
importin alpha-2 subunit (karyopherin alpha-2 subunit) (srp1-alpha) (rag cohort protein 1). [swissprot;acc:p52292] Divided 1.75947 607 1068
septin 1 (larp) (serologically defined breast cancer antigen ny-br- 24). [swissprot;acc:q8wyj6] Low confidence Subtracted 1016.8 1 10499 11515.8
serine/threonine protein phosphatase 2a, 56 kda regulatory subunit, epsilon isoform (pp2a, b subunit, b' epsilon isoform) (pp2a, b subunit, b56 epsilon isoform) (pp2a, b subunit, pr61 epsilon isoform) (pp2a, b subunit, r5 epsilon isoform). [swissprot;acc:q16537] High confidence 3742.8 17738.5 13995.7
synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296] Low confidence Divided 1.82368 0 167.73 305.886
y+l amino acid transporter 1 (y(+)l-type amino acid transporter 1) (y+lat-1) (y+lat1) (monocyte amino acid permease 2) (mop-2). [swissprot;acc:q9um01] 1.12253 1 6991.78 7848.45
zinc finger imprinted 3. [swissprot;acc:q96pe6] Subtracted 383.13 0 2354.3 1971.17
71 cystine/glutamate transporter (amino acid transport system xc-) (xct) (calcium channel blocker resistance protein ccbr1). [swissprot;acc:q9upy5] Divided 1.12253 1 6991.78 7848.45
protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8] Subtracted 1012.9 5339.5 6352.4
serine/threonine protein phosphatase 2a, 55 kda regulatory subunit b, alpha isoform (pp2a, subunit b, b-alpha isoform) (pp2a, subunit b, b55-alpha isoform) (pp2a, subunit b, pr55-alpha isoform) (pp2a, subunit b, r2-alpha isoform). [swissprot;acc:q00007] High confidence Divided 1.54716 4556.78 2945.26
serine/threonine protein phosphatase 2a, 56 kda regulatory subunit, alpha isoform (pp2a, b subunit, b' alpha isoform) (pp2a, b subunit, b56 alpha isoform) (pp2a, b subunit, pr61 alpha isoform) (pp2a, b subunit, r5 alpha isoform). [swissprot;acc:q15172] Subtracted 3742.8 17738.5 13995.7
tubby protein homolog. [swissprot;acc:p50607] 430.7 0 3797.57 4228.27
ubiquitin protein ligase. [refseq;acc:nm_130466] Divided 1.75762 620 352.75
zinc finger protein 233. [refseq;acc:nm_181756] Low confidence Subtracted 383.11 2354.06 1970.95
zona pellucida sperm-binding protein 3 precursor (zona pellucida glycoprotein zp3) (zona pellucida protein c) (sperm receptor) (zp3a/zp3b). [swissprot;acc:p21754] Divided 1.80287 270.432 150.001
72 60s ribosomal protein l21. [swissprot;acc:p46778] High confidence 1.73441 572 992.083
b-raf proto-oncogene serine/threonine-protein kinase (ec 2.7.1.-) (p94) (v-raf murine sarcoma viral oncogene homolog b1). [swissprot;acc:p15056] Subtracted 3733.2 1 17710.9 13977.7
b24o18.3 (pom121 membrane glycoprotein (rat homolog)-like 2). [sptrembl;acc:q96kw2] Low confidence Divided 1.79562 0 271.129 150.995
rab gdp dissociation inhibitor alpha (rab gdi alpha) (gdi-1) (xap-4) (oligophrenin 2). [swissprot;acc:p31150] High confidence Subtracted 427.431 679.449 1106.88
serine/threonine-protein kinase mak (ec 2.7.1.-) (male germ cell- associated kinase). [swissprot;acc:p20794] Low confidence 1001.53 1 9631.47 10633
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6. [refseq;acc:nm_003983] Divided 1.12253 6991.78 7848.45
uncharacterized hematopoietic stem/progenitor cells protein mds026. [sptrembl;acc:q9nz48] High confidence 1.54715 4556.79 2945.28
zinc finger protein 334. [swissprot;acc:q9hcz1] Low confidence Subtracted 383.11 0 2354.02 1970.91
73 eukaryotic translation initiation factor 4b (eif-4b). [swissprot;acc:p23588] Divided 1.12253 1 6991.78 7848.45
intestinal cell kinase isoform a; mak-related kinase; serine/threonine protein kinase. [refseq;acc:nm_014920] Subtracted 997.75 9623.55 10621.3
krab zinc finger protein hzf26 (fragment). [sptrembl;acc:q9bze6] 383.1 0 2353.9 1970.8
protein phosphatase inhibitor 2 (ipp-2). [swissprot;acc:p41236] High confidence Divided 1.73233 65.2968 37.693
sal-like protein 4 (zinc finger protein sall4). [swissprot;acc:q9ujq4] Subtracted 424.22 1965.47 2389.69
serine/threonine protein phosphatase 2a, 55 kda regulatory subunit b, beta isoform (pp2a, subunit b, b-beta isoform) (pp2a, subunit b, b55- beta isoform) (pp2a, subunit b, pr55-beta isoform) (pp2a, subunit b, r2-beta isoform). [swissprot;acc:q00005] Divided 1.54711 1 4556.83 2945.38
serine/threonine protein phosphatase pp1-gamma catalytic subunit (ec 3.1.3.16) (pp-1g). [swissprot;acc:p36873] Subtracted 3708.4 22268.8 18560.4
soluble liver antigen/liver pancreas antigen. [refseq;acc:nm_153825] Low confidence Divided 1.78524 0 688.436 385.626
74 arf gtpase-activating protein. [refseq;acc:nm_133446] 1.78378 66 37
b(0,+)-type amino acid transporter 1 (b(0,+)at) (glycoprotein- associated amino acid transporter b0,+at1). [swissprot;acc:p82251] 1.12253 1 6991.78 7848.45
bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [swissprot;acc:p34820] High confidence 1.71473 0 501.151 859.34
glycogenin-2 (ec 2.4.1.186) (gn-2) (gn2). [swissprot;acc:o15488] Subtracted 421.3 14267.5 14688.8
homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017] 3690.3 1 20446.1 24136.4
melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801] Low confidence 966.8 11285.3 10318.5
serine/threonine protein phosphatase 2a, 55 kda regulatory subunit b, gamma isoform (pp2a, subunit b, b-gamma isoform) (pp2a, subunit b, b55-gamma isoform) (pp2a, subunit b, pr55-gamma isoform) (pp2a, subunit b, r2-gamma isoform) (imypno1). [swissprot;acc:q9y2t4] High confidence Divided 1.54694 4556.99 2945.8
zinc finger protein 195. [swissprot;acc:o14628] Low confidence Subtracted 383.1 0 2353.86 1970.76
75 60s ribosomal protein l21. [swissprot;acc:p46778] High confidence 420.083 572 992.083
hepatocellular carcinoma-associated protein hca3. [refseq;acc:nm_138703] Low confidence 966.8 1 11285.3 10318.5
homeobox protein hox-b4 (hox-2f) (hox-2.6). [swissprot;acc:p17483] High confidence 3690.3 20446.1 24136.4
nadh-ubiquinone oxidoreductase 18 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-18 kda) (ci-18 kda) (complex i- aqdq) (ci-aqdq). [swissprot;acc:o43181] Divided 1.5137 1920.75 2907.43
oligosaccharyl transferase stt3 subunit homolog (b5) (integral membrane protein 1) (tmc). [swissprot;acc:p46977] 1.71412 0 1586.07 925.298
septin 7 (cdc10 protein homolog). [swissprot;acc:q16181] Low confidence 1.11418 1 11616 12942.3
up-regulated in liver cancer 1; similar to development- and differentiation-enhancing factor 2. [refseq;acc:nm_017707] 1.78378 0 66 37
zinc finger protein 230 (zinc finger protein fdzf2). [swissprot;acc:q9uie0] Subtracted 383.09 2353.79 1970.7

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/