MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Value Type	green	Filtered	red	Network Comparison Type	network_comparison	Interaction Map	Rank	description

Results: HTML CSV LaTeX

Showing element 551 to 600 of 77072 in total

Value Type  : Measured
green  : 0.00001
Network Comparison Type  : Divided

Filtered	red	network_comparison	Interaction Map	Rank	description
0	0.00001	1	High confidence	499	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
				500	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
				501	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
				502	brca1 associated protein. [refseq;acc:nm_006768]
			Low confidence	837	gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]
				838	gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]
				839	cobw-like protein. [refseq;acc:nm_018491]
				840	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
				841	gamma-glutamyltransferase. [sptrembl;acc:q14390]
				842	gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]
				843	gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]
	2.31962	231962		7	tbc1 domain family, member 8 (with gram domain); vascular rab-gap/tbc-containing. [refseq;acc:nm_007063]
	13	1300000		6	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
	18	1800000	High confidence	65	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]
	35	3500000		31	dok-like protein. [refseq;acc:nm_024872]
	37	3700000	Low confidence	22	carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 6; macular dystrophy, corneal, 1; carbohydate sulfotransferase 6; corneal n-acetylglucosamine 6-sulfotransferase. [refseq;acc:nm_021615]
				23	carbohydrate (n-acetylglucosamine-6-o) sulfotransferase 2; carbohydrate (chondroitin 6/keratan) sulfotransferase 2. [refseq;acc:nm_004267]
	60	6000000	High confidence	22	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]
	82	8200000		20	ero1-like. [refseq;acc:nm_014584]
	154	15400000		95	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
				96	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
	286	28600000	Low confidence	44	neurogenic locus notch homolog protein 1 precursor (notch 1) (hn1) (translocation-associated notch protein tan-1). [swissprot;acc:p46531]
				45	neurogenic locus notch homolog protein 2 precursor (notch 2) (hn2). [swissprot;acc:q04721]
	364	36400000	High confidence	1	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]
			Low confidence
1	0.00001	1	High confidence	2756	3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]
				2757	nucleosome assembly protein 1-like 1 (nap-1 related protein). [swissprot;acc:p55209]
				2758	nucleosome assembly protein 1-like 2 (brain-specific protein, x- linked). [swissprot;acc:q9ulw6]
				2759	retinoic acid receptor rxr-alpha. [swissprot;acc:p19793]
				2760	t-cell acute lymphocytic leukemia-2 protein (tal-2 protein). [swissprot;acc:q16559]
				2761	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]
				2762	developmentally regulated gtp-binding protein 1 (drg 1). [swissprot;acc:q9y295]
				2763	ring finger protein 3. [refseq;acc:nm_006315]
				2764	ras-related protein rab-11b (gtp-binding protein ypt3). [swissprot;acc:q15907]
				2765	histone h2a.e (h2a/e). [swissprot;acc:q99878]
				2766	ss18-like protein 1 (syt homolog-1). [swissprot;acc:o75177]
				2767	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]
				2768	histone h2a.x (h2a/x). [swissprot;acc:p16104]
				2769	histone h2a.q (h2a/q) (h2a-gl101) (fragment). [swissprot;acc:q16777]
				2770	nipsnap1 protein. [swissprot;acc:q9bpw8]
				2771	t-box transcription factor tbx1 (t-box protein 1) (testis-specific t-box protein). [swissprot;acc:o43435]
				2772	uridine diphosphate glucose pyrophosphatase. [refseq;acc:nm_177533]
				2773	bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [swissprot;acc:p34820]
				2774	dc12 protein. [refseq;acc:nm_020187]
				2775	jerky protein homolog like (hhmjg). [swissprot;acc:q9y4a0]
				2776	bcl-6 interacting corepressor isoform 1. [refseq;acc:nm_017745]
				2777	guanine nucleotide exchange factor mss4 (rab interacting factor). [swissprot;acc:p47224]
				2778	transcription factor mammalian mafa (pancreatic beta-cell specific transcriptional activator). [sptrembl;acc:q8nhw3]
				2779	caveolin-3 (m-caveolin). [swissprot;acc:p56539]
				2780	importin alpha-2 subunit (karyopherin alpha-2 subunit) (srp1-alpha) (rag cohort protein 1). [swissprot;acc:p52292]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.