Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered Gene description Rank green red Value Type Network Comparison Type network_comparison Interaction Map
Results: HTML CSV LaTeX Showing element 551 to 600 of 38536 in total
Filtered  : 0
Network Comparison Type  : Divided
description
Rank
green
red
Value Type
network_comparison
Interaction Map
amiloride-sensitive cation channel 3 isoform a; testis sodium channel 1; proton-gated cation channel subunit; modulatory subunit of asic2a; amiloride-sensitive cation channel 3, testis. [refseq;acc:nm_004769] 569 12.2759 11.7907 Rooted 1.04115 Low confidence
679 12631.5 12377.5 Ranked 1.02052
amiloride-sensitive sodium channel delta-subunit (epithelial na+ channel delta subunit) (delta enac) (nonvoltage-gated sodium channel 1 delta subunit) (scned) (delta nach). [swissprot;acc:p51172] 75 17.4184 5.89418 Squared 2.95519
129 194.326 146.219 Measured 1.32901
498 12.3994 11.7456 Rooted 1.05566
749 12556.6 12412.3 Ranked 1.01163
amiloride-sensitive sodium channel gamma-subunit (epithelial na+ channel gamma subunit) (gamma enac) (nonvoltage-gated sodium channel 1 gamma subunit) (scneg) (gamma nach). [swissprot;acc:p51170] 78 17.0364 5.95216 Squared 2.86222
140 191.013 147.188 Measured 1.29775
570 12.2755 11.7909 Rooted 1.0411
678 12631.8 12377.4 Ranked 1.02055
anaphase promoting complex subunit 11 (hepatocellular carcinoma associated ring finger protein) (hspc214). [swissprot;acc:q9nyg5] 279 9812.39 10614.2 1.08171 High confidence
329 170319 195397 Squared 1.14724
332 14167 15411.3 Measured 1.08783
378 71.5378 74.2677 Rooted 1.03816
606 44134.3 47173.2 Squared 1.06886 Low confidence
704 10847.1 10652.1 Ranked 1.01831
758 4624.67 4679.45 Measured 1.01185
784 35.7083 35.9836 Rooted 1.00771
anchor attachment protein 1; glycophosphatidylinositol anchor attachment 1; anchor attachment protein 1 (gaa1p, yeast) homolog. [refseq;acc:nm_003801] 12 1933 3190 Ranked 1.65028
57 4491.06 1025.97 Squared 4.37738
62 4356 2082 Measured 2.09222
64 66 45.6289 Rooted 1.44645
apoptosis inhibitor fksg2. [swissprot;acc:q9hau6] 261 170628 135280 Squared 1.2613 High confidence
276 12125.1 10817.1 Measured 1.12092
347 17253.9 15175.2 Squared 1.13698 Low confidence
381 55.9159 53.8801 Rooted 1.03778 High confidence
427 11582.7 11276.1 Ranked 1.02719
578 12156 11668.4 1.04179 Low confidence
598 24.7479 25.6322 Rooted 1.03573
650 2283.84 2224.76 Measured 1.02656
aquaporin-cd (aqp-cd) (water channel protein for renal collecting duct) (adh water channel) (aquaporin 2) (collecting duct water channel protein) (wch-cd). [swissprot;acc:p41181] 118 14370.7 12049 Ranked 1.19269 High confidence
134 6483.52 11625.2 Squared 1.79304
142 17.849 21.0926 Rooted 1.18172
164 1354.26 1711.55 Measured 1.26383
205 933.158 1225.35 Squared 1.31312 Low confidence
351 609.23 689.713 Measured 1.13211
616 17.1911 17.7497 Rooted 1.03249
697 12093 12319.2 Ranked 1.01871
arf gtpase-activating protein. [refseq;acc:nm_133446] 70 0.324024 1.03101 Squared 3.18189
74 37 66 Measured 1.78378
87 6.08276 8.12404 Rooted 1.33558
268 16969 14890 Ranked 1.13962
ariadne-2 protein homolog (ari-2) (triad1 protein) (ht005). [swissprot;acc:o95376] 52 4554.5 3284 1.38688 High confidence
211 42.3517 48.2208 Rooted 1.13858
2076.5 2464 Measured 1.18661
324 1500.84 1742.44 Squared 1.16098
614 57580.1 61333 1.06518 Low confidence
629 4967.68 5116.41 Measured 1.02994
636 33.9829 34.9685 Rooted 1.029
652 11715.9 11440.9 Ranked 1.02404

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/