Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Gene Network Comparison Type Rank Value Type Filtered Interaction Map red network_comparison green
Results: HTML CSV LaTeX Showing element 551 to 600 of 77072 in total

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description\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
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26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [source:swissprot;acc:o75832]\vspace{3pt}}}&\multirow{10}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
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63.9816\vspace{3pt}}\\\cline{3-4}\cline{6-9}
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193.995\vspace{3pt}}\\\cline{3-3}\cline{6-9}
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217.589\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
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218.475\vspace{3pt}}\\\cline{3-4}\cline{6-9}
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1.00844\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
47445.6\vspace{3pt}}\\\cline{2-4}\cline{7-9}
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334.41\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
8727.99\vspace{3pt}}\\\cline{3-4}\cline{6-9}
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26736.9\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
2940.4\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
29677.3\vspace{3pt}}\\\cline{3-4}\cline{6-9}
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74.0544\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
2.7015\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
76.7559\vspace{3pt}}\\\cline{3-4}\cline{6-9}
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1634\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
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5853.1\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
418.69\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
6271.79\vspace{3pt}}\\\cline{3-4}\cline{7-9}
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2016\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
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62.2803\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
1.7013\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
63.9816\vspace{3pt}}\\\cline{3-4}\cline{6-9}
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2274\vspace{3pt}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
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197.69\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
3.695\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
193.995\vspace{3pt}}\\\cline{3-3}\cline{6-9}
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2353\vspace{3pt}}&&&\parbox{\wcF}{\vspace{3pt}\noindent
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217.589\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
0.886\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
218.475\vspace{3pt}}\\\cline{3-4}\cline{6-9}
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47846.2\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
400.6\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
47445.6\vspace{3pt}}\\\cline{1-3}\cline{5-9}
\multirow{8}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [source:swissprot;acc:o00232]\vspace{3pt}}}&\multirow{8}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
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328\vspace{3pt}}&&\multirow{8}{*}{\parbox{\wcE}{\vspace{3pt}\noindent
0\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcF}{\vspace{3pt}\noindent
High confidence\vspace{3pt}}}&\parbox{\wcG}{\vspace{3pt}\noindent
6747.71\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
1.14785\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
5878.56\vspace{3pt}}\\\cline{3-4}\cline{7-9}
&&\parbox{\wcC}{\vspace{3pt}\noindent
458\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Rooted\vspace{3pt}}&&&\parbox{\wcG}{\vspace{3pt}\noindent
28.0847\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
1.01531\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
28.5146\vspace{3pt}}\\\cline{3-4}\cline{7-9}
&&\parbox{\wcC}{\vspace{3pt}\noindent
474\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Measured\vspace{3pt}}&&&\parbox{\wcG}{\vspace{3pt}\noindent
2281.12\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
1.00763\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
2263.85\vspace{3pt}}\\\cline{3-4}\cline{7-9}
&&\parbox{\wcC}{\vspace{3pt}\noindent
495\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Ranked\vspace{3pt}}&&&\parbox{\wcG}{\vspace{3pt}\noindent
11725.2\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
1.00195\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
11748.1\vspace{3pt}}\\\cline{3-4}\cline{6-9}
&&\parbox{\wcC}{\vspace{3pt}\noindent
591\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Squared\vspace{3pt}}&&\multirow{4}{*}{\parbox{\wcF}{\vspace{3pt}\noindent
Low confidence\vspace{3pt}}}&\parbox{\wcG}{\vspace{3pt}\noindent
15800.9\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
1.07533\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
14694\vspace{3pt}}\\\cline{3-4}\cline{7-9}
&&\parbox{\wcC}{\vspace{3pt}\noindent
665\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Ranked\vspace{3pt}}&&&\parbox{\wcG}{\vspace{3pt}\noindent
11801.6\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
1.02285\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
11538\vspace{3pt}}\\\cline{3-4}\cline{7-9}
&&\parbox{\wcC}{\vspace{3pt}\noindent
728\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Rooted\vspace{3pt}}&&&\parbox{\wcG}{\vspace{3pt}\noindent
26.1642\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
1.01548\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
26.5693\vspace{3pt}}\\\cline{3-4}\cline{7-9}
&&\parbox{\wcC}{\vspace{3pt}\noindent
785\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Measured\vspace{3pt}}&&&\parbox{\wcG}{\vspace{3pt}\noindent
2349.9\vspace{3pt}}&\parbox{\wcH}{\vspace{3pt}\noindent
1.00797\vspace{3pt}}&\parbox{\wcI}{\vspace{3pt}\noindent
2331.31\vspace{3pt}}\\\hline
nd{longtable}

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/