Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Rank Gene Filtered Value Type Network Comparison Type green Interaction Map red network_comparison
Results: HTML CSV LaTeX Showing element 551 to 600 of 77072 in total
description
Rank
Filtered
Value Type
Network Comparison Type
green
Interaction Map
red
network_comparison
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832] 380 0 Measured Subtracted 2642.79 High confidence 2683.61 40.82
451 Divided 1.01545
584 Squared Subtracted 6490.54 Low confidence 6603.33 112.79
762 Measured 1609.88 1593.68 16.2
763 Squared Divided 6490.54 6603.33 1.01738
771 Measured 1609.88 1593.68 1.01017
793 Rooted 23.2445 23.11 1.00582
797 Subtracted 0.1345
822 Ranked 11854.2 11832.8 21.4
825 Divided 1.00181
1249 1 Squared Subtracted 29419.4 High confidence 26432.8 2986.6
1537 Divided 1.11299
1609 Measured 6242.44 5826.74 1.07134
1646 Subtracted 415.7
1884 8397.56 Low confidence 8137.96 259.6
2056 Divided 1.0319
2061 Rooted Subtracted 63.8594 High confidence 62.2279 1.6315
2064 Divided 1.02622
2256 Ranked Subtracted 218.627 217.419 1.208
2269 Divided 1.00556
2566 Rooted Subtracted 75.1187 Low confidence 72.7032 2.4155
2649 Divided 1.03322
3038 Ranked 197.031 200.303 1.01661
3047 Subtracted 3.272
4026 Squared 45056.5 46258.5 1202
4141 Divided 1.02668
26s proteasome non-atpase regulatory subunit 11 (26s proteasome regulatory subunit s9) (26s proteasome regulatory subunit p44.5). [swissprot;acc:o00231] 744 Measured Subtracted 8727.99 8393.58 334.41
889 Divided 1.03984
1278 Squared Subtracted 29677.3 High confidence 26736.9 2940.4
1282 Rooted 76.7559 Low confidence 74.0544 2.7015
1508 Divided 1.03648
1586 Squared 29677.3 High confidence 26736.9 1.10998
1592 Measured 6271.79 5853.1 1.07153
1634 Subtracted 418.69
2016 Rooted 63.9816 62.2803 1.7013
2026 Divided 1.02732
2174 Ranked 193.995 Low confidence 197.69 1.01905
2274 Subtracted 3.695
2353 218.475 High confidence 217.589 0.886
2367 Divided 1.00407
4818 Squared Subtracted 47445.6 Low confidence 47846.2 400.6
4838 Divided 1.00844
26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232] 136 0 Subtracted 5878.56 High confidence 6747.71 869.15
199 14694 Low confidence 15800.9 1106.9
328 Divided 5878.56 High confidence 6747.71 1.14785
434 Measured Subtracted 2263.85 2281.12 17.27
446 Rooted 28.5146 28.0847 0.4299
458 Divided 1.01531
474 Measured 2263.85 2281.12 1.00763
493 Ranked Subtracted 11748.1 11725.2 22.9

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/