Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Filtered Value Type Gene Rank description green Interaction Map red Network Comparison Type network_comparison
Results: HTML CSV LaTeX Showing element 501 to 550 of 77072 in total
Filtered  : 0
Value Type  : Measured
Rank
description
green
Interaction Map
red
Network Comparison Type
network_comparison
126 calcyphosine. [swissprot;acc:q13938] 635.875 High confidence 472.524 Divided 1.3457
fos-related antigen 2. [swissprot;acc:p15408] 2407.27 Low confidence 3205.98 1.33179
pp3111 protein. [refseq;acc:nm_022156] 530 High confidence 789 Subtracted 259
zinc finger protein 33a (zinc finger protein kox31) (ha0946). [swissprot;acc:q06730] 1968.69 Low confidence 2351.62 382.93
127 alcohol dehydrogenase class iii chi chain (ec 1.1.1.1) (glutathione- dependent formaldehyde dehydrogenase) (ec 1.2.1.1) (fdh). [swissprot;acc:p11766] 1759.22 High confidence 2017.91 258.69
lipopolysaccharide-binding protein precursor (lbp). [swissprot;acc:p18428] 64 86 Divided 1.34375
ubiquinol-cytochrome c reductase complex 7.2 kda protein (ec 1.10.2.2) (cytochrome c1, nonheme 7 kda protein) (complex iii subunit x) (7.2 kda cytochrome c1-associated protein subunit) (hspc119). [swissprot;acc:q9udw1] 511.5 Low confidence 680.5 1.3304
zinc finger protein 347 (zinc finger 1111). [swissprot;acc:q96se7] 1968.53 2351.45 Subtracted 382.92
128 double-stranded rna-specific editase 1 (ec 3.5.-.-) (dsrna adenosine deaminase) (rna editing deaminase 1) (rna editing enzyme 1). [swissprot;acc:p78563] 391 294 Divided 1.32993
importin 9. [refseq;acc:nm_018085] 1397.66 High confidence 1143.55 Subtracted 254.11
mitochondrial 28s ribosomal protein s22 (s22mt) (mrp-s22) (gk002). [swissprot;acc:p82650] 60.8613 81.504 Divided 1.33918
zinc finger protein 93 (zinc finger protein htf34). [refseq;acc:nm_145312] 1968.59 Low confidence 2351.51 Subtracted 382.92
129 amiloride-sensitive sodium channel delta-subunit (epithelial na+ channel delta subunit) (delta enac) (nonvoltage-gated sodium channel 1 delta subunit) (scned) (delta nach). [swissprot;acc:p51172] 194.326 146.219 Divided 1.32901
nucleosome assembly protein 1-like 4 (nucleosome assembly protein 2) (nap2). [swissprot;acc:q99733] 1397.66 High confidence 1143.55 Subtracted 254.11
protein hspc134 (protein cda04). [swissprot;acc:q9by43] 454.837 606.485 Divided 1.33341
zinc finger protein 157 (hzf22). [swissprot;acc:p51786] 1968.53 Low confidence 2351.45 Subtracted 382.92
130 chromodomain y-like protein 2. [refseq;acc:nm_152342] 2799.81 High confidence 3053.31 253.5
maspin precursor (protease inhibitor 5). [swissprot;acc:p36952] 56 42 Divided 1.33333
phosphatidylinositol 4-kinase alpha (ec 2.7.1.67) (pi4-kinase) (ptdins-4-kinase) (pi4k-alpha). [swissprot;acc:p42356] 937.501 Low confidence 707.801 1.32453
zinc finger protein 92 (zinc finger protein htf12) (fragment). [swissprot;acc:q03936] 1968.53 2351.45 Subtracted 382.92
131 1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 851.77 645.504 Divided 1.31954
protein-tyrosine phosphatase, non-receptor type 1 (ec 3.1.3.48) (protein-tyrosine phosphatase 1b) (ptp-1b). [swissprot;acc:p18031] 4658.69 High confidence 4912.01 Subtracted 253.32
serpin b11. [swissprot;acc:q96p15] 56 42 Divided 1.33333
zinc finger protein 211 (zinc finger protein c2h2-25). [swissprot;acc:q13398] 1968.53 Low confidence 2351.45 Subtracted 382.92
132 cytoplasmic antiproteinase 2 (cap2) (cap-2) (protease inhibitor 8) (serpin b8). [swissprot;acc:p50452] 56 High confidence 42 Divided 1.33333
similar to zinc finger protein 85 (zinc finger protein hpf4) (htf1). [refseq;acc:nm_145287] 1968.39 Low confidence 2351.3 Subtracted 382.91
voltage-dependent calcium channel gamma-5 subunit (neuronal voltage- gated calcium channel gamma-5 subunit). [swissprot;acc:q9uf02] 2202 High confidence 1949.36 252.64
wd-repeat protein 5 (wd-repeat protein big-3). [swissprot;acc:q9ugp9] 191.971 Low confidence 251.947 Divided 1.31242
133 bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340] 335 High confidence 252 1.32937
cdc42-binding protein kinase beta; cdc42-binding protein kinase beta (dmpk-like); mrck beta; dmpk-like. [refseq;acc:nm_006035] 1139 Low confidence 874 1.3032
similar to zinc finger protein 136. [refseq;acc:nm_145295] 1968.39 2351.3 Subtracted 382.91
testis-specific chromodomain protein y protein 2. [swissprot;acc:q9y6f7] 2784.59 High confidence 3036.85 252.26
134 mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362] 346.751 260.986 Divided 1.32862
presenilin-like protein 1 (ec 3.4.99.-) (sppl2b protein). [swissprot;acc:q8tct7] 1139 Low confidence 874 1.3032
similar to dna-binding protein; zinc finger protein 253. [refseq;acc:nm_145297] 1968.39 2351.3 Subtracted 382.91
testis-specific chromodomain y protein 1. [swissprot;acc:q9y6f8] 2784.08 High confidence 3036.29 252.21
135 60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268] 476.619 728.65 252.031
maguk p55 subfamily member 2 (mpp2 protein) (discs, large homolog 2). [swissprot;acc:q14168] 203.832 Low confidence 265.513 Divided 1.30261
rna polymerase i transcription factor rrn3. [refseq;acc:nm_018427] 613.614 High confidence 814.485 1.32736
zinc finger protein 132. [swissprot;acc:p52740] 1968.45 Low confidence 2351.36 Subtracted 382.91
136 blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577] 154.324 200.834 Divided 1.30138
glycine cleavage system h protein, mitochondrial precursor. [swissprot;acc:p23434] 1152.06 High confidence 903.767 Subtracted 248.293
transcription factor e2f2 (e2f-2). [swissprot;acc:q14209] 1150.51 1526.38 Divided 1.3267
zinc finger protein 84 (zinc finger protein hpf2). [swissprot;acc:p51523] 1968.39 Low confidence 2351.3 Subtracted 382.91
137 blood group rh(d) polypeptide (rhesus d antigen) (rhxiii) (rh polypeptide 2) (rhpii). [swissprot;acc:q02161] 154.279 200.759 Divided 1.30127
heat shock factor binding protein 1. [swissprot;acc:o75506] 1233.41 High confidence 1631.18 1.3225
ribonucleoside-diphosphate reductase m1 chain (ec 1.17.4.1) (ribonucleotide reductase large chain). [swissprot;acc:p23921] 7276.12 7520.78 Subtracted 244.66
zinc finger protein 121 (zinc finger protein 20) (fragment). [swissprot;acc:p58317] 1968.32 Low confidence 2351.22 382.9
138 60s ribosomal protein l17 (l23). [swissprot;acc:p18621] 1906.28 High confidence 1663.73 242.55
blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577] 154.279 Low confidence 200.759 Divided 1.30127

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/