MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Value Type	Filtered	green	red	Network Comparison Type	network_comparison	Interaction Map	Rank	description

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Value Type  : Measured
Filtered  : 0

green	red	Network Comparison Type	network_comparison	Interaction Map	Rank	description
322.947	409.972	Divided	1.26947	Low confidence	148	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]
		Subtracted	87.025		469
323.433	410.28	Divided	1.26852		150	williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]
		Subtracted	86.847		470
323.685	410.457	Divided	1.26808		151	williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]
		Subtracted	86.772		471
327.517	630.942	Divided	1.92644	High confidence	55	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]
		Subtracted	303.425		103
330.189	638.862	Divided	1.93484		54	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]
		Subtracted	308.673		101
335	252	Divided	1.32937		133	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]
		Subtracted	83		314
336.584	261.105	Divided	1.28908		157	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]
				Low confidence	143
		Subtracted	75.479	High confidence	319
				Low confidence	497
339.154	403.827	Divided	1.19069	High confidence	207	cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]
		Subtracted	64.673		331
339.779	361.601	Divided	1.06422	Low confidence	485	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]
		Subtracted	21.822		733
346.751	260.986	Divided	1.32862	High confidence	134	mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362]
		Subtracted	85.765		309
351.772	198.964	Divided	1.76802		68	protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981]
		Subtracted	152.808		209
352.75	620	Divided	1.75762		71	ubiquitin protein ligase. [refseq;acc:nm_130466]
		Subtracted	267.25		119
354.349	305.111	Divided	1.16138	Low confidence	318	poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366]
		Subtracted	49.238		599
359.631	494.417	Divided	1.37479	High confidence	120	signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556]
		Subtracted	134.786		238
359.98	377.445	Divided	1.04852		382	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]
		Subtracted	17.465		433
362.023	379.489	Divided	1.04825		383	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]
		Subtracted	17.466		432
362.955	535.61	Divided	1.47569	Low confidence	101	60s ribosomal protein l37a. [swissprot;acc:p12751]
		Subtracted	172.655		301
363	304	Divided	1.19408	High confidence	203	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]
				Low confidence	296
		Subtracted	59	High confidence	343
				Low confidence	555
368.317	320.752	Divided	1.14829	High confidence	229	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]
		Subtracted	47.565		370
369.011	424.258	Divided	1.14972		227	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]
		Subtracted	55.247		349
372.961	287.903	Divided	1.29544		145	likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033]
		Subtracted	85.058		312
375.343	455.789	Divided	1.21433	Low confidence	179	alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]
		Subtracted	80.446		481
377.574	291.639	Divided	1.29466	High confidence	146	cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2]
		Subtracted	85.935		308

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.