MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

green	description	network_comparison	Interaction Map	Value Type	Network Comparison Type	Gene	Filtered	red	Rank

Results: HTML CSV LaTeX

Showing element 501 to 550 of 38536 in total

green  : 0.00001
Interaction Map  : High confidence
Network Comparison Type  : Divided

description	network_comparison	Value Type	Filtered	red	Rank
ergic-53 protein precursor (er-golgi intermediate compartment 53 kda protein) (lectin, mannose-binding 1) (gp58) (intracellular mannose specific lectin mr60). [swissprot;acc:p49257]	1	Rooted	1	0.00001	3177
ero1-like. [refseq;acc:nm_014584]	159148	Squared	0	1.59148	8
	905539	Rooted		9.05539
	8200000	Measured		82	20
erythroid differentiation-related factor 1. [refseq;acc:nm_015608]	1		1	0.00001	3095
		Ranked
		Squared
		Rooted
eukaryotic initiation factor 4a-i (eif-4a-i) (eif4a-i). [swissprot;acc:p04765]		Measured			2868
		Ranked
		Squared
		Rooted
eukaryotic initiation factor 4a-ii (eif-4a-ii) (eif4a-ii). [swissprot;acc:q14240]		Measured			2888
		Ranked
		Squared
		Rooted
exocyst complex component exo70. [swissprot;acc:q9upt5]		Measured			2781
		Ranked
		Squared
		Rooted
ezrin-binding partner pace-1 isoform 1. [refseq;acc:nm_020423]		Measured			3228
		Ranked
		Squared
		Rooted
fatty aldehyde dehydrogenase (ec 1.2.1.3) (aldehyde dehydrogenase, microsomal) (aldh class 3). [swissprot;acc:p51648]		Measured			3181
		Ranked
		Squared
		Rooted
ferrochelatase, mitochondrial precursor (ec 4.99.1.1) (protoheme ferro-lyase) (heme synthetase). [swissprot;acc:p22830]		Measured			3185
		Ranked
		Squared
		Rooted
fibrillin 1 precursor. [swissprot;acc:p35555]		Measured			2844
		Ranked
		Squared
		Rooted
fibrillin 2 precursor. [swissprot;acc:p35556]		Measured			2955
		Ranked
		Squared
		Rooted
fibrillin 3. [refseq;acc:nm_032447]		Measured			2939
		Ranked
		Squared
		Rooted
flap endonuclease-1 (ec 3.-.-.-) (maturation factor 1) (mf1). [swissprot;acc:p39748]		Measured			2831
		Ranked
		Squared
		Rooted
fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075]		Measured			2907
		Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.