Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered green Gene network_comparison Value Type Interaction Map Network Comparison Type Rank red description

Results: HTML CSV LaTeX

Showing element 501 to 550 of 38536 in total

Filtered

: 0
Network Comparison Type

: Divided

green	network_comparison	Value Type	Interaction Map	Rank	red	description
12.7411	1.73139	Rooted	Low confidence	31	7.3589	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
12.753	1.24434			120	10.2488	selenoprotein t. [swissprot;acc:q9nzj3]
12.7728	1.04784			540	12.1897	mitochondrial carrier protein mgc4399. [refseq;acc:nm_032315]
12.8712	1.02033			697	13.1329	cln3 protein (battenin) (batten disease protein). [swissprot;acc:q13286]
12.8903	1.03648		High confidence	384	13.3606	60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]
12.9333	1.12923		Low confidence	205	14.6047	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]
12.9538	1.41698			67	18.3553	alpha 2 globin. [refseq;acc:nm_000517]
12.9627	1.41651			68	18.3618	hemoglobin gamma-a and gamma-g chains. [swissprot;acc:p02096]
12.9659	1.41635			69	18.3642	myoglobin. [swissprot;acc:p02144]
13.034	1.22258		High confidence	124	10.6611	f-actin capping protein alpha-2 subunit (capz alpha-2). [swissprot;acc:p47755]
13.1421	1.08499	Squared		390	12.1126	alpha-nac protein. [sptrembl;acc:q9h009]
13.1443	1.08826	Squared		387	12.0783	nascent-polypeptide-associated complex alpha polypeptide. [refseq;acc:nm_005594]
13.1909	1319090	Rooted		93	0.00001	cab2. [refseq;acc:nm_033419]
13.3054	1.17432		Low confidence	147	15.6248	cg4853 gene product. [refseq;acc:nm_145313]
13.373	1.02724		High confidence	433	13.7373	rab gdp dissociation inhibitor alpha (rab gdi alpha) (gdi-1) (xap-4) (oligophrenin 2). [swissprot;acc:p31150]
13.4012	1.01149		Low confidence	760	13.5552	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]
13.448	2.55866	Squared		83	34.4089	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
13.4716	1.15887	Rooted		164	15.6118	piwi-like 2; miwi like. [refseq;acc:nm_018068]
13.5207	1.38596		High confidence	69	18.7392	cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]
13.5494	1.11829		Low confidence	224	15.1522	protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]
13.5647	1.80277		High confidence	40	24.454	cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336]
13.6105	1.35766		High confidence	76	10.025	testis-specific protein tpx-1 precursor (cysteine-rich secretory protein-2) (crisp-2). [swissprot;acc:p16562]
13.6518	1.11204		Low confidence	344	15.1813	espin. [refseq;acc:nm_031475]
13.7156	1.08451			405	12.6468	poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366]
13.7907	1.10039			358	15.1752	estrogen-related receptor gamma (estrogen receptor related protein 3) (err gamma-2). [swissprot;acc:o75454]
13.8207	1.38377	Squared	High confidence	218	19.1247	testis-specific protein tpx-1 precursor (cysteine-rich secretory protein-2) (crisp-2). [swissprot;acc:p16562]
13.8963	1.03439	Rooted		394	13.4343	tbp-associated factor 9l; neuronal cell death-related protein; taf9-like rna polymerase ii, tata box binding protein (tbp)-associated factor, 31 kd; neuronal cell death-related gene in neuron-7; transcription associated factor tafii31l; transcription initiation factor iid, 31kd subunit. [refseq;acc:nm_015975]
13.9084	1.17928			143	16.4019	importin 4. [refseq;acc:nm_024658]
13.9284	1.12149			232	15.6205	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]
14.0846	1.2322			121	17.3551	myosin vi. [swissprot;acc:q9um54]
14.0846	1.2322		Low confidence	123	17.3551	myosin vi. [swissprot;acc:q9um54]
14.1963	1.09552		High confidence	267	12.9585	transcription factor mafk (erythroid transcription factor nf-e2 p18 subunit). [swissprot;acc:o60675]
14.2577	1.09465		High confidence	268	13.0249	transcription factor mafg (v-maf musculoaponeurotic fibrosarcoma oncogene homolog g) (hmaf). [swissprot;acc:o15525]
14.3004	1.13534		Low confidence	195	16.2358	adapter-related protein complex 1 sigma 1b subunit (sigma-adaptin 1b) (adaptor protein complex ap-1 sigma-1b subunit) (golgi adaptor ha1/ap1 adaptin sigma-1b subunit) (clathrin assembly protein complex 1 sigma- 1b small chain) (sigma 1b subunit of ap-1 clathrin) (dc22). [swissprot;acc:p56377]
14.3151	1.11026		High confidence	246	12.8935	maguk p55 subfamily member 2 (mpp2 protein) (discs, large homolog 2). [swissprot;acc:q14168]
14.3181	1.02893		Low confidence	637	14.7323	dynactin 1 (150 kda dynein-associated polypeptide) (dp-150) (dap-150) (p150-glued) (p135). [swissprot;acc:q14203]
14.3236	1.12835		Low confidence	208	16.162	stromal membrane-associated protein; stromal membrane-associated protein smap1a. [refseq;acc:nm_021940]
14.3333	1.3721	Measured	High confidence	121	19.6667	4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]
14.4058	1.82337	Rooted	High confidence	39	7.90063	potassium voltage-gated channel, shal-related subfamily, member 2; voltage-sensitive potassium channel; voltage-gated potassium channel kv4.2. [refseq;acc:nm_012281]
14.4058	1.82337		Low confidence	25	7.90063
14.4887	1.35259			84	19.5973	dynamin-like 120 kda protein, mitochondrial precursor (optic atrophy 1 gene protein). [swissprot;acc:o60313]
14.4914	1.16292			159	16.8523	helicase/primase complex protein. [refseq;acc:nm_138336]
14.5086	1.05434		High confidence	332	15.297	basic proline-rich peptide p-e (ib-9). [swissprot;acc:p02811]
14.5738	1.26912		High confidence	115	18.4959	estrogen-related receptor gamma (estrogen receptor related protein 3) (err gamma-2). [swissprot;acc:o75454]
14.6565	1.08063		Low confidence	408	15.8382	glycerol kinase (ec 2.7.1.30) (atp:glycerol 3-phosphotransferase) (glycerokinase) (gk). [swissprot;acc:p32189]
14.6595	1.07978			410	15.829	glycerol kinase, testis specific 1 (ec 2.7.1.30) (atp:glycerol 3- phosphotransferase) (glycerokinase) (gk). [swissprot;acc:q14409]
14.6672	1.07735			419	15.8017	glycerol kinase, testis specific 2 (ec 2.7.1.30) (atp:glycerol 3- phosphotransferase) (glycerokinase) (gk). [swissprot;acc:q14410]
14.6994	1.16915			152	17.1858	f-actin capping protein alpha-2 subunit (capz alpha-2). [swissprot;acc:p47755]
14.7003	1.05005		High confidence	349	15.4361	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]
14.7392	1.67654		High confidence	45	8.79142	elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/